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  • Zdravljenje prekomerno aktivnega sečnega mehurja z zdravili = Pharmacotherapy of detrusor overactivity
    Tršinar, Bojan
    Overactive bladder syndrome is characterized by involuntary contractions of the detrusor muscle during bladder filling. The principal forms of detrusor overactivity are detrusor hyperreflexia and ... detrusor instability. These different types of overactivity can result from neurogenic, myogenic and othercauses (acidosis, hypoxia, structural changes in the detrusor muscle). The characteristic symptoms of an overactive bladder are frequency and urgency, along with urge incontinence. The clinical picture, urinalysis and cystometry are essential for diagnosis. The mainstay of current pharmacological treatment involves the use of muscarinic receptor antagonists (oxybutynin, tolterodine, propiverine, trospium chloride). The use of beta adrenoreceptor agonists (clenbuterol), alpha adrenoreceptor antagonists (tamsulosin), tachykinins antagonists, potassium channel openers (pinacidil, cromakalim), vanilloids (capsaicin) and Botulinum toxin are still in the phaseof preclinical and clinical studies.
    Vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 43, supl. 1, mar. 2004, str. 77-84)
    Vrsta gradiva - prispevek na konferenci ; neleposlovje za odrasle
    Leto - 2004
    Jezik - slovenski
    COBISS.SI-ID - 17917401

vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 43, supl. 1, mar. 2004, str. 77-84)

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