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Patients with oral erosive and cutaneous lichen planus may have antibodies directed against the chronic ulcerative stomatitis protein antigen of 70-kDaCozzani, Emanuele ...Objective: The aim of this study is to verify whether stratified epithelium-specific antinuclear antibodies are present in the sera of patientswith erosive oral lichen planus and cutaneous lichen ... planus. Methods: We studied the pre-immune and immune serum of a rabbit immunized with a peptide corresponding to the N-terminus of the 70-kDa antigen chronic ulcerative stomatitis protein; sera from two patients, one with oral erosive lichen planus and one with cutaneous lichen planus who presented stratified epithelium-specific antinuclear antibodies at high titer; and a third serum from a patient with cutaneous lichen planus without stratified epithelium-specific antinuclear antibodies. Results: We demonstrated that the protein bands recognized by the serum of the rabbit immunized with an epitope of chronic ulcerative stomatitis protein co-migrated by SDS-PAGE with the protein bands recognized by the serum of a patient affected by oral erosive lichen planus and by the serum of a patient with cutaneous lichen planus, bothcontaining antibodies directed against a 70-kDa antigen. Conclusion: Our results confirm that antibodies specifically directed against the chronic ulcerative stomatitis protein are not a distinctive marker of chronic ulcerative stomatitis, but may also be detected in oral erosive and cutaneous lichen planus.Vir: Acta dermatovenerologica Alpina, Panonica et Adriatica. - ISSN 1318-4458 (Vol. 17, no. 3, sep. 2008, str. 120-124)Vrsta gradiva - članek, sestavni delLeto - 2008Jezik - angleškiCOBISS.SI-ID - 24952025
Avtor
Cozzani, Emanuele |
Cacciapuoti, Marco |
Di Marco, Eddi |
Zerega, Barbara |
Descalzi Cancedda, Fiorella |
Parodi, Aurora
Teme
Lichen Planus |
Gingivitis, Necrotizing Ulcerative |
Antibodies, Antinuclear |
Fluorescent Antibody Technique, Indirect |
Immunoblotting |
Keratinocytes |
Lihen planus |
Fluorescenčno protitelo, tehnika indirektna |
Imunoblot |
Gingivitis nekrotizirajoči, ulcerativni |
Protitelesa protijedrna |
Keratinociti |
dermatologija |
kožne bolezni |
protitelesa
vir: Acta dermatovenerologica Alpina, Panonica et Adriatica. - ISSN 1318-4458 (Vol. 17, no. 3, sep. 2008, str. 120-124)
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Cozzani, Emanuele | |
Cacciapuoti, Marco | |
Di Marco, Eddi | |
Zerega, Barbara | |
Descalzi Cancedda, Fiorella | |
Parodi, Aurora |
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