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  • Prevalence of oral pathology and periodontal disease in HIV-1 infected patients in Slovenia = Pogostnost bolezni ustne sluznice in obzobnih tkiv pri pacientih, okuženih s HIV-1, v Sloveniji
    Artnik, Barbara ...
    Background. prevalence of oral pathology and periodontal disease is frequent in HIV infected patients. In this study we examined the oral mucosa and periodontal tissues in HIV-1 infected patients in ... Slovenia, and compared the oral findings to the progression of HIV-1 infection. Patients and methods. We examined 35 HIV-1 infected patients (27 males and 8 females; age: 19-56 years;mean: 38.8 years), and 35 gender and age matched seronegative control subjects. Oral mucosa lesions were assessed by an oral clinical examination. Plaque deposits and periodontal tissues were evaluated by the established clinical parameters: Plaque Index (PI), Gingival Index (GI), probing depth (PD) and epithelial attachment loss (EAL). The stage of HIV-1 infection was assessed by the number of CD4+ T-lymphocytes and the number of HIV-1 RNA- copies/ml in the patients sera. A statistical analysis was performed by the Student's t-test and the Pearson's correlation coefficient. Results. In 10 patients (28.6%) we found clinical manifestations of pseudomembranous oral candidiasis. Ten patients (28.6%) also showed the manifestation of hairy leukoplakia on the lateral margins of the tongue. No oral mucosa lesions were observed in the control group. HIV-1 infected patients with observed in the control group. HIV-1 infected patients with oral candidiasis and hairy leukoplakia hada a significantly lower number (t = 2.22, P < 0.05; t = 2.23, P< 0.05, respectively) of CD4+ T-lymphocytes, and a non-significantly higher number of HIV-1 RNA copies/ml in the sera comparing to the values found in HIV-1 infect patients without oral candidiasis and hairy leukoplakia.(Abstracttruncated at 2000 characters.)
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 67, supl. 2, jun. 1998, str. II-79-II-82)
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - angleški
    COBISS.SI-ID - 7664089

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