Aim: Cigarette smoking is major cause of diseases as heart disease, stroke, chronic lung disease and lung cancer, which causes of death in elderly. But, regardless of the age of the patients, the ...likelihood of these illnesses declining in the period following the release of cigarette. Methods: 35 patients were included to study older than 65 age and independent in daily life activities were admitted to Kackar State Hospital with nonspecific complaints and unknown chronic illnesses. Vital signs, saturation, ECG findings, smoking and alcohol dependence, sleep quality, BMI, bone densitometry, minimental test and geriatric depression scales were evaluated. Data analysis was performed with SPSS. Results: Of patients were 48.5% male, 51.5% female, mean age was 82 and mean BMI was 19.5. Additional diseases diagnosed after the examination of our patients were 45% HT, 8% COPD and 28% osteoporosis disease. The average saturation was 94 and the heart rate was 75. When smoking status was assessed, 68% of patients never smoked in their life and there were no patients currently ongoing. 95% of COPD patients had previous history of smoking. Conclusions: When the concepts of healthy and super aging are considered, smoking is seen an important risk for additional diseases in old ages. In our country, significant progress has been made in smoking cessation policlinics in recently. To raise awareness about healthy old age and especially to question the situation of smoking in patients 65 aged and to inform smokers to encourage them to quit smoking.
Purpose
The objective of this study is to investigate the effects of laparoscopic sleeve gastrectomy (LSG) on the polysomnographic parameters related to OSAS.
Materials and Methods
We conducted this ...3-year prospective cohort study in a tertiary care center between December 2016 and December 2019. In total, we enrolled 31 patients with severe obesity who underwent full-night polysomnography (PSG) before LSG. Later, the patients were re-evaluated by full-night PSG 12 months after the surgery.
Results
The mean age of the patients was 44.1 ± 9.6 years. The mean body mass index (BMI) decreased significantly from a mean value of 49.8 ± 8.5 kg/m
2
at baseline to 33.2 ± 8.2 kg/m
2
and a percent BMI (%BMI) reduction of 33.8 ± 10.4% and a percent total weight loss (%TWL) of 35.4 ± 10.8% was achieved on the same day of the postsurgical PSG (
p
< 0.001). There was a remarkable improvement in the AHI (baseline: 36.1 ± 27.1, 12 months after the surgery: 10.3 ± 11.8; difference: 25.8 ± 22.8 events per hour) (
p
< 0.001). Importantly, there was a decrease in the percentage of non-rapid eye movement (NREM) 2 (
p
< 0.001), whereas NREM 3 and REM stages witnessed a significant increase (
p
= 0.001 and
p
< 0.001, respectively) after the surgery.
Conclusion
The results of this study showed that weight loss after LSG yields improvement not only in AHI but also in many polysomnographic parameters such as sleep quality and desaturation indices.
Caregiver Burden in Pulmonary Patients Yılmaz Kara, Bilge; Toprak, Derya; Kara, Ekrem ...
Journal of gerontological social work,
04/2023, Letnik:
66, Številka:
3
Journal Article
Recenzirano
Caregiving has become an increasingly important medical and social issue in recent decades. We performed a cross-sectional study on pulmonary patients and accompanying informal caregivers who were ...hospitalized in the chest disease ward of a tertiary center in Turkey between January 2020 and April 2021. Informal caregivers were asked to complete the Zarit Caregiver Burden Interview. A total of 141 inpatients (39% female, mean age: 76.8 ± 10.2 years) and their informal caregivers (77% female, mean age: 54 ± 11.9 years) were evaluated. The caregivers were classified as light to medium burden (group 1, burden score ≤40) and medium to heavy burden (group 2, burden score >40). The mean burden score was 35.7 ± 13.3 points. The number of female caregivers was higher in group 2 (p = 0.025). There was a positive correlation between the burden score and female gender (p = 0.002) and the number of chronic diseases of caregivers (p = 0.020). Statistical analysis revealed a negative correlation between the burden score and the level of education (r = > −0.174, p = 0.040). Caregiver burden is related to the characteristics of the caregiver rather than those of the patient being cared for. Female caregivers with lower education and more than one chronic disease perceive a higher caregiver burden.
Granulomatous lung disease (GLD) is caused by a wide range of conditions and it is challenge for pulmonologist. A detailed history of exposures is fundamental in GDL and has been found pivotal to ...reach a precise diagnosis.
Between September 2014 and December 2016, the distribution of patients diagnosed with granulomatous lymphadenitis in the mediastinal/hilar lymph nodes by endobronchial ultrasound (EBUS) or mediastinoscopy was analyzed. To be listed as 'confident', a diagnosis of sarcoidosis required compatible histological, radiological and clinical findings in conjunction with negative cultures. Infectious entities listed as 'confident' had either microorganisms in tissue section, positive culture, positive serology or positive antigen detection in a consistent clinical pathological setting.
Granulomatous lymphadenitis was detected in 110 patients. The included 110 cases consisted of 70.9% women and median age of 53 (range 44-61) years. The final diagnosis of the patients was accepted to be sarcoidosis in 79 (71.8%), sarcoid like granulomas in 7 (6.4%), tuberculosis in 4 (3.6%), silicosis in 4 (3.6%), drug-associated granuloma in 2 (1.8%), hypersensitivity pneumonitis in 1 (0.9%), Chron disease in 1 (0.9%), unspecified in 12 (10.9%). Three patients were classified as tuberculosis based on culture.
In this study, we found that the most common cause of granulomatous lymphadenitis was sarcoidosis. Contrary to expectations, the number of patients diagnosed with tuberculosis was very low.
Pulmonary Actinomycosis in a Diabetic Patient Yilmaz Kara, Bilge; Kotan, Abdurrahman; Senol, Muzaffer ...
Turkish Thoracic Journal,
09/2019, Letnik:
20, Številka:
1
Journal Article
Recenzirano
Odprti dostop
Introduction: Pulmonary actinomycosis is still a compelling issue for clinicians. Since it may resemble other infectious and malignant diseases clinically, the diagnosis can often be made only after ...a surgical procedure. Presently described is a rare case of pulmonary actinomycosis in a patient with uncontrolled diabetes mellitus. Case Presentation: A 71-year-old male patient was admitted with chronic cough, sputum production and weakness. The patient had the same complaints for about 9 months. Oral antibiotics were prescribed several times. Since no clinical or radiological progress was obtained, the patient was hospitalized for further investigation. He had a past history of hypertension, diabetes mellitus, benign prostate hypetrophy and ischemic heart disease for more than ten years. He had a surgical procedure for dental prostesis approximately two months before the sympthoms’ onset. On physical examination, the general condition was good, vitals were normal, and coarse cracles were present on auscultation above the right lung. Biochemical findings were as follows: Erythrocyte sedimentation rate: 59 mm/hr, leukocyte count: 19.870/mm3 hemoglobin: 12.6 g/dL, haematocrit: 39.6%, fasting glucose: 375 mg/dL crp: 12.6 (normal limits: 0-0.5). On chest X-ray, a nonhomogeneous opacity in the right middle and lower zones was observed. Peribronchial thickening, focal consolidation areas, pleural irregularities, and pleural fluid reaching up to 4.5 cm thickness on the right hemithorax and right hilar lympadenopaties were observed on thorax computed tomography. Fiberoptic bronchoscopy was performed in order to rule out malignancy. The inlet of the anterior segment of the right lower lobe bronchus was narrowed by external compression. There was no endobronchial lesion. Mucosal punch biopsy and bronchial lavage fluid were obtained for microbiological and pathological investigation. There was no microbiological growth on bacterial cultures. Pathological examination demonstrated presence of chronic suppuration findings with Actinomyces like organisms. 200 mg/kg ampicillin theraphy was administered intravenously. After 5 days, dramatic clinical and laboratory response were noted despite there was no marked improvement on radiologic findings. Conclusion: Actinomyces are microaerophilic, gram positive commensals of the oral cavity which have the ability to erode through tissue planes under certain conditions. Pulmonary infection with Actinomyces species is uncommon, and usually results from aspiration of oropharyngeal secretions in those with chronic dental infections, extension from a cervicofacial infection, or hematogenous spread from a distant source. Chest imaging may provide some clues, but a definitive diagnosis often relies on a pathological examination of the infected tissue.
The results of standard chemotherapy in lung cancer are not very satisfactory, so it is important to identify genetic mutations that provide targeted therapies. Recent reports have suggested ...influences of racial difference on the frequency of mutation in lung cancer. We aimed to determine the frequency and regional distribution of genetic mutations of non-small cell lung cancer (NSCLC) in Turkey.
Regional distribution of genetic mutations in lung cancer in Turkey (REDIGMA) study was carried out as a prospective, cross-sectional, observational study in a large number of centers in which lung cancer patients were followed and could perform genetic mutation analysis on patients' biopsy materials.
The 703 patients (77.7% male, mean age 63.3 ± 12.5 years) who were diagnosed as NSCLC from 25 different centers were included in the study. Tumor samples from patients were reported as 87.1% adenocarcinoma, 6.4% squamous cell carcinoma and 6.5% other. Mutation tests were found to be positive in 18.9% of these patients. The mutations were 69.9% EGFR, 26.3% ALK, 1.6% ROS and 2.2% PDL. Mutations were higher in women and non-smokers (p<0.000, p<0.001). Again, the frequency of mutations in adenocarcinoma was higher in metastatic disease. There was no difference between the patient's age, area of residence, comorbidity and clinical stage and mutation frequency.
Our study revealed that the EGFR mutation rate in Turkey with NSCLC was similar to East European, African-American and Caucasian patients, and was lower than in East Asia.
PDF
