Liposarcoma of the breast is a rare form of cancerous tumor that can be mistaken for primary breast cancer. A recent instance involved a woman who was 54 years old and went in for her annual ...screening mammogram. The mammogram revealed that she had a 1 cm focal asymmetry of equal density in her right axillary tail, approximately 9 cm from the nipple. After nine months, the patient observed a rapidly growing mass even though the initial ultrasound scan did not detect anything unusual. A targeted mammogram demonstrated a large and dense mass confined to the right axillary tail, followed by an ultrasound scan that revealed a heterogeneous hyperechoic, echogenic mass. Histopathology after surgery showed that the patient had an undifferentiated pleomorphic breast liposarcoma. This diagnosis was reached after the patient underwent surgery.Liposarcoma of the breast is a concerning condition that needs careful management and close monitoring, although it is relatively uncommon. Early detection of the patient's condition and prompt treatment can help improve the patient's prognosis. This can be accomplished by remaining vigilant with routine screenings and following up on any unusual findings or changes in breast tissue. However, it is possible to diagnose this condition as primary breast cancer incorrectly; consequently, healthcare providers need to conduct comprehensive evaluations to ensure diagnostic accuracy and the delivery of appropriate treatment.
Breast cancer is widespread around the world and can be cured if diagnosed at an early stage. Digital mammograms are used as the most effective imaging modalities for the diagnosis of breast cancer. ...However, mammography images suffer from low contrast, background noise as well as contrast as non-coherency among the regions, and these factors makes breast cancer diagnosis challenging. These problems can be overcome by using a new image enhancement technique. The objective of this research work is to enhance mammography images to improve the overall process of segmentation and classification of breast cancer diagnosis. We proposed the image enhancement for mammogram images, as well as the ablation of the pectoral muscle. The image enhancement technique involves several steps. In the first step, we process the mammography images in three channels (red, green and blue), the second step is based on the uniformity of the background on morphological operations, and the third step is to obtain a well-contrasted image using principal component analysis (PCA). The fourth step is based on the removal of the pectoral muscle using a seed-based region growth technique, and the last step contains the coherence of the different regions of the image using a second order Gaussian Laplacian (LoG) and an oriented diffusion filter to obtain a much-improved contrast image. The proposed image enhancement technique is tested with our data collected from different hospitals in Qassim health cluster Qassim province Saudi Arabia, and it contains the five Breast Imaging and Reporting System (BI-RADS) categories and this database contained 11,194 images (the images contain carnio-caudal (CC) view and mediolateral oblique(MLO) view of mammography images), and we used approximately 700 images to validate our database. We have achieved improved performance in terms of peak signal-to-noise ratio, contrast, and effective measurement of enhancement (EME) as well as our proposed image enhancement technique outperforms existing image enhancement methods. This performance of our proposed method demonstrates the ability to improve the diagnostic performance of the computerized breast cancer detection method.
In today’s world, a brain tumor is one of the most serious diseases. If it is detected at an advanced stage, it might lead to a very limited survival rate. Therefore, brain tumor classification is ...crucial for appropriate therapeutic planning to improve patient life quality. This research investigates a deep-feature-trained brain tumor detection and differentiation model using classical/linear machine learning classifiers (MLCs). In this study, transfer learning is used to obtain deep brain magnetic resonance imaging (MRI) scan features from a constructed convolutional neural network (CNN). First, multiple layers (19, 22, and 25) of isolated CNNs are constructed and trained to evaluate the performance. The developed CNN models are then utilized for training the multiple MLCs by extracting deep features via transfer learning. The available brain MRI datasets are employed to validate the proposed approach. The deep features of pre-trained models are also extracted to evaluate and compare their performance with the proposed approach. The proposed CNN deep-feature-trained support vector machine model yielded higher accuracy than other commonly used pre-trained deep-feature MLC training models. The presented approach detects and distinguishes brain tumors with 98% accuracy. It also has a good classification rate (97.2%) for an unknown dataset not used to train the model. Following extensive testing and analysis, the suggested technique might be helpful in assisting doctors in diagnosing brain tumors.
Brain tumors reduce life expectancy due to the lack of a cure. Moreover, their diagnosis involves complex and costly procedures such as magnetic resonance imaging (MRI) and lengthy, careful ...examination to determine their severity. However, the timely diagnosis of brain tumors in their early stages may save a patient’s life. Therefore, this work utilizes MRI with a machine learning approach to diagnose brain tumor severity (glioma, meningioma, no tumor, and pituitary) in a timely manner. MRI Gaussian and nonlinear scale features are extracted due to their robustness over rotation, scaling, and noise issues, which are common in image processing features such as texture, local binary patterns, histograms of oriented gradient, etc. For the features, each MRI is broken down into multiple small 8 × 8-pixel MR images to capture small details. To counter memory issues, the strongest features based on variance are selected and segmented into 400 Gaussian and 400 nonlinear scale features, and these features are hybridized against each MRI. Finally, classical machine learning classifiers are utilized to check the performance of the proposed hybrid feature vector. An available online brain MRI image dataset is utilized to validate the proposed approach. The results show that the support vector machine-trained model has the highest classification accuracy of 95.33%, with a low computational time. The results are also compared with the recent literature, which shows that the proposed model can be helpful for clinicians/doctors for the early diagnosis of brain tumors.
Breast cancer is widespread worldwide and can be cured if diagnosed early. Using digital mammogram images and image processing with artificial intelligence can play an essential role in breast cancer ...diagnosis. As many computerized algorithms for breast cancer diagnosis have significant limitations, such as noise handling and varying or low contrast in the images, it can be difficult to segment the abnormal region. These challenges could be overcome by proposing a new pre-processing model, exploring its impact on the post-processing module, and testing it on an extensive database. In this research work, the three-step method is proposed and validated on large databases of mammography images. The first step corresponded to the database classification, followed by the second step, which removed the pectoral muscle from the mammogram image. The third stage utilized new image-enhancement techniques and a new segmentation module to detect abnormal regions in a well-enhanced image to diagnose breast cancer. The pre-and post-processing modules are based on novel image processing techniques. The proposed method was tested using data collected from different hospitals in the Qassim Health Cluster, Qassim Province, Saudi Arabia. This database contained the five categories in the Breast Imaging and Reporting and Data System and consisted of 2892 images; the proposed method is analyzed using the publicly available Mammographic Image Analysis Society database, which contained 322 images. The proposed method gives good contrast enhancement with peak-signal to noise ratio improvement of 3 dB. The proposed method provides an accuracy of approximately 92% on 2892 images of Qassim Health Cluster, Qassim Province, Saudi Arabia. The proposed method gives approximately 97% on the Mammographic Image Analysis Society database. The novelty of the proposed work is that it could work on all Breast Imaging and Reporting and Data System categories. The performance of the proposed method demonstrated its ability to improve the diagnostic performance of the computerized breast cancer detection method.
This study aimed to examine the validity and reproducibility of strain elastography (SE) for detecting prostate cancer (PCa) in patients with elevated prostate-specific antigen (PSA) levels. The ...study included 107 patients with elevated PSA levels. All eligible patients underwent transrectal ultrasound (TRUS) with real-time elastography (RTE) to detect suspicious lesions. Two readers independently evaluated the lesions and assigned a strain ratio and elastography score to each lesion. Histopathology was used as a reference standard to estimate the validity of RTE in predicting malignant lesions. An intraclass correlation (ICC) was performed to detect reliability of the strain ratios and elastography scores. TRUS-guided biopsy detected malignancies in 64 (59.8%) patients. TRUS with RTE revealed 122 lesions. The strain ratio index (SRI) cut-off values to diagnose malignancy were 4.05 and 4.35, with sensitivity, specificity, and accuracy of 94.7%, 91.3%, and 93.4%, respectively. An elastography score > 3 was the best cut-off value for detecting malignancy. According to readers, the sensitivity, specificity, and accuracy were 91.3-94.7%, 89.5-93.4%, and 91.3-90.9%, respectively. Excellent inter-reader agreement was recorded for SRI and elastography scores, with ICC of 0.937 and 0.800, respectively. SE proves to be an efficient tool for detecting PCa with high accuracy in patients with elevated PSA levels.
Background
There is limited data in the literature regarding the role of nonarthrographic MRI for detecting biceps pulley (BP) lesions.
Purpose
To assess the accuracy of nonarthrographic MRI for ...detecting BP lesions, and to evaluate the diagnostic value of various MRI signs (superior glenohumeral ligament discontinuity/nonvisibility, long head of biceps (LHB) displacement sign or subluxation/dislocation, LHB tendinopathy, and supraspinatus and subscapularis tendon lesions) in detecting such lesions.
Study Type
Retrospective.
Population
84 patients (32 in BP‐lesion group and 52 in BP‐intact group‐as confirmed by arthroscopy).
Field Strength/Sequence
1.5‐T, T1‐weighted turbo spin echo (TSE), T2‐weighted TSE, and proton density‐weighted TSE spectral attenuated inversion recovery (SPAIR) sequences.
Assessment
Three radiologists independently reviewed all MRI data for the presence of BP lesions and various MRI signs. The MRI signs and final MRI diagnoses were tested for accuracy regarding detecting BP lesions using arthroscopy results as the reference standard. Furthermore, the inter‐reader agreement (IRA) between radiologists was determined.
Statistical Tests
Student's t‐tests, Chi‐squared, and Fisher's exact tests, and 4‐fold table test were used. The IRA was calculated using Kappa statistics. A P‐value <0.05 was considered statistically significant.
Results
The sensitivity, specificity, and accuracy of nonarthrographic MRI for detecting BP lesions were 65.6%–78.1%, 90.4%–92.3%, and 81%–86.9%, respectively. The highest accuracy was noticed for the LHB displacement sign (84.5%–86.9%), and the highest sensitivity was registered for the LHB tendinopathy sign (87.5%). Furthermore, the highest specificity was observed for the LHB displacement sign and LHB subluxation/dislocation sign (98.1%–100%). The IRA regarding final MRI diagnosis and MRI signs of BP lesions was good to very good (κ = 0.76–0.98).
Data Conclusion
Nonarthrographic shoulder MRI may show good diagnostic accuracy for detecting BP lesions. The LHB displacement sign could serve as the most accurate and specific sign for diagnosis of BP lesions.
Level of Evidence
3
Technical Efficacy
Stage 2
Worldwide, COVID-19 is a highly contagious epidemic that has affected various fields. Using Artificial Intelligence (AI) and particular feature selection approaches, this study evaluates the aspects ...affecting the health of students throughout the COVID-19 lockdown time. The research presented in this paper plays a vital role in indicating the factor affecting the health of students during the lockdown in the COVID-19 pandemic. The research presented in this article investigates COVID-19’s impact on student health using feature selections. The Filter feature selection technique is used in the presented work to statistically analyze all the features in the dataset, and for better accuracy. ReliefF (TuRF) filter feature selection is tuned and utilized in such a way that it helps to identify the factors affecting students’ health from a benchmark dataset of students studying during COVID-19. Random Forest (RF), Gradient Boosted Decision Trees (GBDT), Support Vector Machine (SVM), and 2- layer Neural Network (NN), helps in identifying the most critical indicators for rapid intervention. Results of the approach presented in the paper identified that the students who maintained their weight and kept themselves busy in health activities in the pandemic, such student’s remained healthy through this pandemic and study from home in a positive manner. The results suggest that the 2- layer NN machine-learning algorithm showed better accuracy (90%) to predict the factors affecting on health issues of students during COVID-19 lockdown time.