The aim of this work was to prepare a nanoemulsion containing the essential oil of
resin and to evaluate the larvicidal activity and the residual larvicidal effect against
The essential oil was ...identified by gas chromatography coupled to a mass spectrometer, and the nanoemulsions were prepared using a low-energy method and characterized by photon correlation spectroscopy. The results indicated the major constituents as
-cimene (27.70%) and α-Pinene (22.31%). Nanoemulsions had kinetic stability and a monomodal distribution in a hydrophilic-lipophilic balance of 14 with particle diameters of 115.56 ± 1.68 nn and zeta potential of -29.63 ± 3.46 mV. The nanoemulsion showed larvicidal action with LC
= 2.91 µg∙mL
and residual larvicidal effect for 72 h after application to
larvae. Consequently, the nanobiotechnological product derived from the essential oil of
resin could be used against infectious disease vectors.
This work aimed to prepare a nanoemulsion containing the essential oil of the
resin and evaluate its biocidal activities against the different stages of development of the
mosquito. Ovicide, ...pupicide, adulticide and repellency assays were performed. The main constituents were
-cymene (27.70%) and
-pinene (22.31%). The developed nanoemulsion showed kinetic stability and monomodal distribution at a hydrophilic-lipophilic balance of 14 with a droplet size of 115.56 ± 1.68 nn and a zeta potential of -29.63 ± 3.46 mV. The nanoemulsion showed insecticidal action with LC
0.404 µg·mL
for the ovicidal effect. In the pupicidal test, at the concentration of 160 µg·mL
, 100% mortality was reached after 24 h. For adulticidal activity, a diagnostic concentration of 200 µg·mL
(120 min) was determined. In the repellency test, a concentration of 200 µg·mL
during the 180 min of the test showed a protection index of 77.67%. In conclusion, the nanobiotechnological product derived from the essential oil of
resin can be considered as a promising colloid that can be used to control infectious disease vectors through a wide range of possible modes of applications, probably as this bioactive delivery system may allow the optimal effect of the
terpenes in aqueous media and may also induce satisfactory delivery to air interfaces.
This article examines the potential for wind and solar energy generation in the state of Amapá, Brazil, using ERA5 data from between 1991 and 2020. Key metrics considered include wind power density, ...capacity factor, photovoltaic potential, and concentrated solar power output. Analyses revealed pronounced wind speeds offshore during summer and in continental regions during spring. Solar irradiance was notably higher in the spring. Differences in wind potential were observed between northern and southern offshore areas. Concentrated solar power efficiency and photovoltaic potential were influenced by location and cloud cover, respectively. Overall, summer presents the best offshore wind energy potential, while spring is optimal for onshore solar energy in Amapá. This study underscores the importance of understanding local climatic patterns when planning energy installations in the region.
Leprosy is a much‐feared incapacitating infectious disease caused by Mycobacterium leprae or M lepromatosis, annually affecting roughly 200,000 people worldwide. During host‐pathogen interaction, M ...leprae subverts the immune response, leading to development of disease. Throughout the last few decades, the impact of energy metabolism on the control of intracellular pathogens and leukocytic differentiation has become more evident. Mitochondria play a key role in regulating newly‐discovered immune signaling pathways by controlling redox metabolism and the flow of energy besides activating inflammasome, xenophagy, and apoptosis. Likewise, this organelle, whose origin is probably an alphaproteobacterium, directly controls the intracellular pathogens attempting to invade its niche, a feature conquered at the expense of billions of years of coevolution. In the present review, we discuss the role of reduced host cell mitochondrial activity during M leprae infection and the consequential fates of M leprae and host innate immunity. Conceivably, inhibition of mitochondrial energy metabolism emerges as an overlooked and novel mechanism developed by M leprae to evade xenophagy and the host immune response.
Cactus pear biomass has the potential for bioethanol production in dry regions. However, its low solids concentration and pH variations may hinder the process of alcoholic fermentation. The ...objectives of this study were as follows: (1) to evaluate the effects of harvest time and season on biomass pH and dry matter concentration of cladodes of two cactus pear species commonly used as forage (
Nopalea cochenillifera
and
Opuntia stricta
); (2) to compare the hydrolysis of fresh and dried biomass (10% w v
−1
solids); (3) to compare increasing periods of two temperatures (65 °C or 105 °C) to concentrate the biomass to 10% and 30% solids; and (4) to perform enzymatic hydrolysis and fermentation of biomass dried to 30% solids. Biomass pH ranged from 3.0 to 5.6, from early morning to late afternoon, with higher diurnal variation during the dry season, when their solids concentrations were higher than in the rainy season (12–16% × 7–10%). Hydrolyzed fresh and dried biomass had similar glucose, xylose, and galacturonic acid concentrations. Drying at 105 °C for 12 h was the best temperature and period to reach 30% of solids. The enzymatic hydrolysis of the biomass dried to 30% solids yielded 65.3 and 80.0 g of glucose L
−1
. After fermentations (33 °C; 8 h;
Saccharomyces cerevisiae
), ethanol was produced to 29.4 and 37.5 g L
-1
from
N. cochenillifera
and
O. stricta
biomasses, respectively. Therefore, early morning during the dry season is the best moment to harvest the cladodes, whose biomass can be partially dried at 105 °C for 12 h to 30% solids load before being hydrolyzed and fermented for bioethanol production. This procedure reduces the time, energy, and inputs needed in the process.
Clinically validate the Nursing Outcome Behavior of falls prevention in hospitalized patients.
This was a cross-sectional study developed at a public university hospital with a sample of 45 patients. ...The data collection was performed through the evaluation of four nurses, with a double used the instrument with the constitutive and operational definitions of the indicators and magnitudes of the Fall Prevention Behavior Result, while the other pair did not use such definitions.
When applying the non-parametric analysis of variance by the Friedman test, ten indicators showed statistical differences between the inferences made by the evaluators for each patient. In relation to the intraclass correlation coefficient, confidence interval and p value assigned to each indicator of the scale, most of the indicators were statistically significant.
The instrument referring to the Fall Behavior Outcome Behavior was considered valid for the study population.
Objective: The objective of this research was to analyze the contributions of green marketing as a source of competitive advantage for organizations. Methodology: The research adopted the ...systematic review methodology, following the PRISMA guidelines, to analyze articles on sustainable management practices, green marketing and competitive advantage. Search platforms such as Google Acadêmico and Scielo were used, with inclusion criteria for scientific articles in Portuguese published between 2018 and 2023. Exclusion criteria were applied to discard non-pertinent works, resulting in the selection of 7 articles. Results and data analysis: As a result, it was possible to see that the systematic review highlighted green marketing as a source of competitive advantage for organizations, by integrating environmental concerns into market strategies. This enables differentiation, operational efficiency, and more sustainable production processes. In addition, the adoption of sustainable practices attracts consumers engaged with sustainability, increasing the profitability of production models. Certifications such as ISO 14001 demonstrate a commitment to sustainability, giving competitive advantage. Thus, green marketing favors the company's image and, at the same time, engages consumers in sustainable practices, contributing to the positioning of the organization in the market as a socio-environmentally responsible company. Conclusion: It is concluded, therefore, that green marketing not only improves the competitiveness of companies, but also fosters a culture of sustainability and preservation of natural resources, representing a significant contribution to organization, society and the environment.
Objective: to determine clinical and epidemiological profile of surgical patients with ocular dryness and to the Nursing diagnostic and risk of dry eye, in the postoperative period. Methods: ...cross-sectional study, with 82 patients in the postoperative period. For analysis, it were used frequencies, the distribution centers’ measures and respectives variabilities. Results: equivalent prevalence between ocular dryness and the nursing diagnosis. The average age was 57.7 years for patients with ocular dryness and 59.6 years for those with risk diagnosis. In both groups, there was a predominance of females, cardiovascular surgeries and general anesthetic usage. The length of the surgical procedure averaged 105 minutes for patients with ocular dryness and 67.5 minutes for those with risk diagnosis. Conclusion: predominance of women in middle age undergoing elective surgeries by cardiovascular reasons for both groups, however, with distinct time of surgical procedure.
O objetivo desta pesquisa foi avaliar o suporte organizacional para aprendizagem e o impacto do Curso de Aperfeiçoamento em Gestão Pública na percepção dos gestores Técnico-Administrativos em ...Educação de uma instituição pública de educação, ciência e tecnologia do Nordeste do Brasil. Trata-se de uma pesquisa qualitativa, com modo de investigação no estudo de caso e de objetivo descritiva. Para o levantamento dos dados utilizou-se de entrevista estruturada por meio do MAIS (Modelo de Avaliação Integrado e Somativo), proposto por Jairo Borges-Andrade, Gardênia Abbad e Luciana Mourão. Os dados coletados foram tratados em planilhas eletrônicas e os resultados demonstram que: quanto ao suporte organizacional, existiram condições organizacionais favoráveis e havia compromisso da organização com a aprendizagem das novas competências dos trabalhadores, bem como, houve a absorção pelos indivíduos/ grupos de trabalho sobre o quanto a organização valoriza suas contribuições de novos conhecimentos. Quanto ao impacto do treinamento, tem-se que ficou constatado que houve melhorias no desempenho individual dos servidores treinados através de uma nova forma de desempenhar antigas tarefas a partir das novas competências adquiridas.
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