We describe the development of a Proton Range Radiography system with an imaging area of 30×30cm2 for two dimensional mapping of the integrated density in a target.
Proton transmission radiographic ...images are produced by measuring, with a pair of position-sensitive detectors (GEM chambers), the direction of the protons transmitted through the patient and, with a stack of scintillators, the residual range of the protons leaving the patient. To match the data rate requirements of an in-beam diagnostic, a novel data acquisition system for the tracking detectors has been designed to operate at 1MHz data flow. Laboratory tests exposing the GEM detector with high flux X-rays confirm the fast response of the new data acquisition system. Images of several phantoms have been recorded to demonstrate the GEM position accuracy.
TERA Foundation has proposed and designed hadrontherapy facilities based on novel linacs, i.e. high gradient linacs which accelerate either protons or light ions. The overall length of the linac, and ...therefore its cost, is almost inversely proportional to the average accelerating gradient. With the scope of studying the limiting factors for high gradient operation and to optimize the linac design, TERA, in collaboration with the CLIC Structure Development Group, has conducted a series of high gradient experiments. The main goals were to study the high gradient behavior and to evaluate the maximum gradient reached in 3 and 5.7 GHz structures to direct the design of medical accelerators based on high gradient linacs. This paper summarizes the results of the high power tests of 3.0 and 5.7 GHz single-cell cavities.
Accelerators for hadrontherapy: From Lawrence cyclotrons to linacs Amaldi, U.; Bonomi, R.; Braccini, S. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
2010, Letnik:
620, Številka:
2
Journal Article
Recenzirano
Hadrontherapy with protons and carbon ions is a fast developing methodology in radiation oncology. The accelerators used and planned for this purpose are reviewed starting from the cyclotrons used in ...the thirties. As discussed in the first part of this paper, normal and superconducting cyclotrons are still employed, together with synchrotrons, for proton therapy while for carbon ion therapy synchrotrons have been till now the only option. The latest developments concern a superconducting cyclotron for carbon ion therapy, fast-cycling high frequency linacs and ‘single room’ proton therapy facilities. These issues are discussed in the second part of the paper by underlining the present challenges, in particular the treatment of moving organs.
We describe the development, construction and preliminary results obtained with medium-size Multi-Gap Resistive Plate Chambers prototypes designed to detect and localize 511keV photons for Positron ...Emission Tomography imaging applications. The devices are intended for in-beam monitoring of the treatment plans throughout deep tumor therapy with hadron beams; emphasis is put on achieving coincidence time resolutions of few hundred ps, in order to exploit optimized reconstruction algorithm and reduce the heavy non-correlated background contributions distinctive of this operation. Using technologies developed for high energy physics experiments, the detectors can be built for covering large areas, thus leading the way to the conception of full-body PET systems at low cost.
Construction, test and operation of a proton range radiography system Amaldi, U.; Bianchi, A.; Chang, Y-H. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
02/2011, Letnik:
629, Številka:
1
Journal Article
Recenzirano
We describe a Proton Range Radiography system with an imaging area of 10×10
cm
2, deploying a pair of Gas Electron Multiplier position-sensitive detectors and a scintillator stack to measure the ...residual proton range after crossing a target. The detector has been tested in the laboratory and in beam exposures at the Paul Scherrer Institute; images recorded with several phantoms of variable thickness and composition confirm the sub-millimetre accuracy and few percent energy resolution of the instrument. A new device with identical design and larger acceptance, 30×30
cm
2, is in construction.
Advanced Quality Assurance for CNAO Amaldi, U.; Hajdas, W.; Iliescu, S. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
05/2010, Letnik:
617, Številka:
1
Journal Article
Recenzirano
We describe the test results of a Proton Range Radiography system, designed to provide in-beam integrated density images of the patients before treatment at hadrontherapy centers. The instrument ...includes a set of position-sensitive detectors and a scintillator stack read out with solid-state sensors to record the Bragg energy loss profile for each track.
Fast readout of GEM detectors for medical imaging Bucciantonio, M.; Amaldi, U.; Kieffer, R. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
08/2013, Letnik:
718
Journal Article
Recenzirano
We describe the design and implementation of a fast data acquisition (DAQ) system for Gas Electron Multiplier (GEM) trackers applied to imaging and dosimetry in hadrontherapy. Within the AQUA project ...of the TERA foundation a prototype of Proton Range Radiography of 30×30cm2 active area has been designed and built to provide in-beam integrated density images of the patient before treatment. It makes use of a pair of GEMs to record position and direction of protons emerging from the target.
A fast data acquisition rate close to 1MHz will allow obtaining a good resolution in-beam proton radiography in a few seconds. A dedicated fast front-end circuit for GEM detectors (GEMROC by AGH-Crakow University) is read by the FPGA based DAQ card (GR_DAQ), developed by the AQUA group. The same system is under evaluation (within the ENVISION European project) to realize the in-vivo dosimetry, based on detecting secondary light particles during the treatment of the patient.
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