Purpose
To determine whether early goal-directed therapy (EGDT) reduces mortality compared with other resuscitation strategies for patients presenting to the emergency department (ED) with septic ...shock.
Methods
Using a search strategy of PubMed, EmBase and CENTRAL, we selected all relevant randomised clinical trials published from January 2000 to January 2015. We translated non-English papers and contacted authors as necessary. Our primary analysis generated a pooled odds ratio (OR) from a fixed-effect model. Sensitivity analyses explored the effect of including non-ED studies, adjusting for study quality, and conducting a random-effects model. Secondary outcomes included organ support and hospital and ICU length of stay.
Results
From 2395 initially eligible abstracts, five randomised clinical trials (
n
= 4735 patients) met all criteria and generally scored high for quality except for lack of blinding. There was no effect on the primary mortality outcome (EGDT: 23.2 % 495/2134 versus control: 22.4 % 582/2601; pooled OR 1.01 95 % CI 0.88–1.16,
P
= 0.9, with heterogeneity
I
2
= 57 %;
P
= 0.055). The pooled estimate of 90-day mortality from the three recent multicentre studies (
n
= 4063) also showed no difference pooled OR 0.99 (95 % CI 0.86–1.15),
P
= 0.93 with no heterogeneity (
I
2
= 0.0 %;
P
= 0.97). EGDT increased vasopressor use (OR 1.25 95 % CI 1.10–1.41;
P
< 0.001) and ICU admission OR 2.19 (95 % CI 1.82–2.65);
P
< 0.001. Including six non-ED randomised trials increased heterogeneity (
I
2
= 71 %;
P
< 0.001) but did not change overall results pooled OR 0.94 (95 % CI 0.82 to 1.07);
P
= 0.33.
Conclusion
EGDT is not superior to usual care for ED patients with septic shock but is associated with increased utilisation of ICU resources.
ABSTRACT
We present measurements of the local core-collapse supernova (CCSN) rate using SN discoveries from the Palomar Transient Factory (PTF). We use a Monte Carlo simulation of hundreds of ...millions of SN light-curve realizations coupled with the detailed PTF survey detection efficiencies to forward model the SN rates in PTF. Using a sample of 86 CCSNe, including 26 stripped-envelope SNe (SESNe), we show that the overall CCSN volumetric rate is $r^\mathrm{CC}_v=9.10_{-1.27}^{+1.56}\times 10^{-5}\, \text{SNe yr}^{-1}\, \text{Mpc}^{-3}\, h_{70}^{3}$ at 〈z〉 = 0.028, and the SESN volumetric rate is $r^\mathrm{SE}_v=2.41_{-0.64}^{+0.81}\times 10^{-5}\, \text{SNe yr}^{-1}\, \text{Mpc}^{-3}\, h_{70}^{3}$. We further measure a volumetric rate for hydrogen-free superluminous SNe (SLSNe-I) using eight events at z ≤ 0.2 of $r^\mathrm{SLSN-I}_v=35_{-13}^{+25}\, \text{SNe yr}^{-1}\text{Gpc}^{-3}\, h_{70}^{3}$, which represents the most precise SLSN-I rate measurement to date. Using a simple cosmic star formation history to adjust these volumetric rate measurements to the same redshift, we measure a local ratio of SLSN-I to SESN of ${\sim}1/810^{+1500}_{-94}$, and of SLSN-I to all CCSN types of ${\sim}1/3500^{+2800}_{-720}$. However, using host galaxy stellar mass as a proxy for metallicity, we also show that this ratio is strongly metallicity dependent: in low-mass (logM* < 9.5 M⊙) galaxies, which are the only environments that host SLSN-I in our sample, we measure an SLSN-I to SESN fraction of $1/300^{+380}_{-170}$ and $1/1700^{+1800}_{-720}$ for all CCSN. We further investigate the SN rates a function of host galaxy stellar mass, and show that the specific rates of all CCSNe decrease with increasing stellar mass.
We present Hubble Space Telescope (HST) Wide Field Camera 3 UV and near-IR (nIR) imaging of 21 Superluminous Supernovae (SLSNe) host galaxies, providing a sensitive probe of star formation and ...stellar mass within the hosts. Comparing the photometric and morphological properties of these host galaxies with those of core-collapse supernovae (CCSNe) and long-duration gamma-ray bursts (LGRBs), we find SLSN hosts are fainter and more compact at both UV and nIR wavelengths, in some cases we barely recover hosts with absolute magnitude around MV ≈ −14. With the addition of ground based optical observations and archival results, we produce spectral energy distribution fits to these hosts, and show that SLSN hosts possess lower stellar mass and star formation rates. This is most pronounced for the hydrogen deficient Type-I SLSN hosts, although Type-II H-rich SLSN host galaxies remain distinct from the bulk of CCSNe, spanning a remarkably broad range of absolute magnitudes, with ∼30 per cent of SLSNe-II arising from galaxies fainter than M
nIR ∼ −14. The detection of our faintest SLSN hosts increases the confidence that SLSNe-I hosts are distinct from those of LGRBs in star formation rate and stellar mass, and suggests that apparent similarities in metallicity may be due to the limited fraction of hosts for which emission line metallicity measurements are feasible. The broad range of luminosities of SLSN-II hosts is difficult to describe by metallicity cuts, and does not match the expectations of any reasonable UV-weighted luminosity function, suggesting additional environmental constraints are likely necessary to yield hydrogen rich SLSNe.
Abstract
We present the results of a Hubble Space Telescope WFC3/F160W Snapshot survey of the host galaxies of 39 long-duration gamma-ray bursts (LGRBs) at z < 3. We have non-detections of hosts at ...the locations of four bursts. Sufficient accuracy to astrometrically align optical afterglow images and determine the location of the LGRB within its host was possible for 31/35 detected hosts. In agreement with other work, we find the luminosity distribution of LGRB hosts is significantly fainter than that of a star formation rate-weighted field galaxy sample over the same redshift range, indicating LGRBs are not unbiasedly tracing the star formation rate. Morphologically, the sample of LGRB hosts is dominated by spiral-like or irregular galaxies. We find evidence for evolution of the population of LGRB hosts towards lower luminosity, higher concentrated hosts at lower redshifts. Their half-light radii are consistent with other LGRB host samples where measurements were made on rest-frame UV observations. In agreement with recent work, we find their 80 per cent enclosed flux radii distribution to be more extended than previously thought, making them intermediate between core-collapse supernova (CCSN) and superluminous supernova (SLSN) hosts. The galactocentric projected-offset distribution confirms LGRBs as centrally concentrated, much more so than CCSNe and similar to SLSNe. LGRBs are strongly biased towards the brighter regions in their host light distributions, regardless of their offset. We find a correlation between the luminosity of the LGRB explosion site and the intrinsic column density, NH, towards the burst.
ABSTRACT
We present optical and near-infrared (NIR) observations of the Type Icn supernova (SN Icn) 2022ann, the fifth member of its newly identified class of SNe. Its early optical spectra are ...dominated by narrow carbon and oxygen P-Cygni features with absorption velocities of ∼800 km s−1; slower than other SNe Icn and indicative of interaction with a dense, H/He-poor circumstellar medium (CSM) that is outflowing slower than typical Wolf–Rayet wind velocities of >1000 km s−1. We identify helium in NIR spectra 2 weeks after maximum and in optical spectra at 3 weeks, demonstrating that the CSM is not fully devoid of helium. Unlike other SNe Icn, the spectra of SN 2022ann never develop broad features from SN ejecta, including in the nebular phase. Compared to other SNe Icn, SN 2022ann has a low luminosity (o-band absolute magnitude of ∼−17.7), and evolves slowly. The bolometric light curve is well-modelled by 4.8 M⊙ of SN ejecta interacting with 1.3 M⊙ of CSM. We place an upper limit of 0.04 M⊙ of 56Ni synthesized in the explosion. The host galaxy is a dwarf galaxy with a stellar mass of 107.34 M⊙ (implied metallicity of log(Z/Z⊙) ≈ 0.10) and integrated star-formation rate of log (SFR) = −2.20 M⊙ yr−1; both lower than 97 per cent of galaxies observed to produce core-collapse supernovae, although consistent with star-forming galaxies on the galaxy Main Sequence. The low CSM velocity, nickel and ejecta masses, and likely low-metallicity environment disfavour a single Wolf–Rayet progenitor star. Instead, a binary companion is likely required to adequately strip the progenitor and produce a low-velocity outflow.
ABSTRACT
The design and analysis of time-domain sky surveys require the ability to simulate accurately realistic populations of core-collapse supernova (SN) events. We present a set of spectral ...time-series templates designed for this purpose, for both hydrogen-rich (Type II, IIn, and IIb) and stripped-envelope (Type Ib, Ic, and Ic-BL) core-collapse SNe. We use photometric and spectroscopic data for 67 core-collapse SNe from the literature, and for each generate a time-series spectral template. The techniques used to build the templates are fully data driven with no assumption of any parametric form or model for the light curves. The template-building code is open source, and can be applied to any transient for which well-sampled multiband photometry and multiple spectroscopic observations are available. We extend these spectral templates into the near-ultraviolet to λ ≃ 1600 Å using observer-frame ultraviolet photometry. We also provide a set of templates corrected for host galaxy dust extinction, and provide a set of luminosity functions that can be used with our spectral templates in simulations. We give an example of how these templates can be used by integrating them within the popular SN simulation package snana, and simulating core-collapse SNe in photometrically selected cosmological Type Ia SN samples, prone to contamination from core-collapse events.
Context. Super-luminous supernovae (SLSNe) are rare events defined as being significantly more luminous than normal terminal stellar explosions. The source of the additional power needed to achieve ...such luminosities is still unclear. Discoveries in the local Universe (i.e. z < 0.1) are scarce, but afford dense multi-wavelength observations. Additional low-redshift objects are therefore extremely valuable. Aims. We present early-time observations of the type I SLSN ASASSN-18km/SN 2018bsz. These data are used to characterise the event and compare to literature SLSNe and spectral models. Host galaxy properties are also analysed. Methods. Optical and near-IR photometry and spectroscopy were analysed. Early-time ATLAS photometry was used to constrain the rising light curve. We identified a number of spectral features in optical-wavelength spectra and track their time evolution. Finally, we used archival host galaxy photometry together with H II region spectra to constrain the host environment. Results. ASASSN-18km/SN 2018bsz is found to be a type I SLSN in a galaxy at a redshift of 0.0267 (111 Mpc), making it the lowest-redshift event discovered to date. Strong C II lines are identified in the spectra. Spectral models produced by exploding a Wolf-Rayet progenitor and injecting a magnetar power source are shown to be qualitatively similar to ASASSN-18km/SN 2018bsz, contrary to most SLSNe-I that display weak or non-existent C II lines. ASASSN-18km/SN 2018bsz displays a long, slowly rising, red “plateau” of >26 days, before a steeper, faster rise to maximum. The host has an absolute magnitude of –19.8 mag (r), a mass of M⋆ = 1.5−0.33+0.08 × 109 M⊙ M ⋆ = 1.5 − 0.33 + 0.08 × 10 9 M ⊙ $ M_\star=1.5_{-0.33}^{+0.08}\times10^9M_\odot $ , and a star formation rate of = 0.50−0.19+2.22 M⊙ yr −1 = 0.50 − 0.19 + 2.22 M ⊙ yr − 1 $ =0.50_{-0.19}^{+2.22}M_\odot\text{yr}^{-1} $ . A nearby H II region has an oxygen abundance (O3N2) of 8.31 ± 0.01 dex.
We introduce a Hubble Space Telescope (HST)/Space Telescope Imaging Spectrograph (STIS) stellar census of R136a, the central ionizing star cluster of 30 Doradus. We present low resolution ...far-ultraviolet STIS spectroscopy of R136 using 17 contiguous 52 arcsec × 0.2 arcsec slits which together provide complete coverage of the central 0.85 parsec (3.4 arcsec). We provide spectral types of 90 per cent of the 57 sources brighter than m
F555W = 16.0 mag within a radius of 0.5 parsec of R136a1, plus 8 additional nearby sources including R136b (O4 If/WN8). We measure wind velocities for 52 early-type stars from C ivλλ1548–51, including 16 O2–3 stars. For the first time, we spectroscopically classify all Weigelt and Baier members of R136a, which comprise three WN5 stars (a1–a3), two O supergiants (a5–a6) and three early O dwarfs (a4, a7, a8). A complete Hertzsprung–Russell diagram for the most massive O stars in R136 is provided, from which we obtain a cluster age of 1.5
$^{+0.3}_{-0.7}$
Myr. In addition, we discuss the integrated ultraviolet spectrum of R136, and highlight the central role played by the most luminous stars in producing the prominent He ii λ1640 emission line. This emission is totally dominated by very massive stars with initial masses above ∼100 M⊙. The presence of strong He ii λ1640 emission in the integrated light of very young star clusters (e.g. A1 in NGC 3125) favours an initial mass function extending well beyond a conventional upper limit of 100 M⊙. We include montages of ultraviolet spectroscopy for Large Magellanic Cloud O stars in the appendix. Future studies in this series will focus on optical STIS medium resolution observations.
We present the first cosmological parameter constraints using measurements of type Ia supernovae (SNe Ia) from the Dark Energy Survey Supernova Program (DES-SN). The analysis uses a subsample of 207 ...spectroscopically confirmed SNe Ia from the first three years of DES-SN, combined with a low-redshift sample of 122 SNe from the literature. Our "DES-SN3YR" result from these 329 SNe Ia is based on a series of companion analyses and improvements covering SN Ia discovery, spectroscopic selection, photometry, calibration, distance bias corrections, and evaluation of systematic uncertainties. For a flat ΛCDM model we find a matter density . For a flat wCDM model, and combining our SN Ia constraints with those from the cosmic microwave background (CMB), we find a dark energy equation of state , and . For a flat w0waCDM model, and combining probes from SN Ia, CMB and baryon acoustic oscillations, we find and . These results are in agreement with a cosmological constant and with previous constraints using SNe Ia (Pantheon, JLA).
Calcium-rich supernovae (SNe) represent a significant challenge for our understanding of the fates of stellar systems. They are less luminous than other SN types and they evolve more rapidly to ...reveal nebular spectra dominated by strong calcium lines with weak or absent signatures of other intermediate- and iron-group elements, which are seen in other SNe. Strikingly, their explosion sites also mark them out as distinct from other SN types. Their galactocentric offset distribution is strongly skewed to very large offsets (∼1/3 are offset >20 kpc), meaning they do not trace the stellar light of their hosts. Many of the suggestions to explain this extreme offset distribution have invoked the necessity for unusual formation sites such as globular clusters or dwarf satellite galaxies, which are therefore difficult to detect. Building on previous work attempting to detect host systems of nearby Ca-rich SNe, we here present Hubble Space Telescope imaging of five members of the class – three exhibiting large offsets and two coincident with the disc of their hosts. We find no underlying sources at the explosion sites of any of our sample. Combining with previous work, the lack of a host system now appears to be a ubiquitous feature amongst Ca-rich SNe. In this case the offset distribution is most readily explained as a signature of high-velocity progenitor systems that have travelled significant distances before exploding.
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