This research aimed to examine predictors of discrepancies between actual and ideal body images, specifically body fat and muscularity discrepancies, in kinesiology students.
Volunteer participants (
...= 174, men = 112, women = 62) filled out the sex-specific Somatomorphic Matrices (NSM-M and SM-F) as well as The Positive and Negative Perfectionism Scale (PNPS), Rosenberg Self-esteem Scale (RSE), and the Eating Attitudes Test (EAT-26) using paper and pencil tools.
The median and Mann-Whitney
tests were used to determine sex differences, and regression analyses were used to determine the contribution of sex, perfectionism, self-esteem, and eating attitudes in explaining the variances in body fat and muscularity dissatisfaction. The results showed no sex differences in body fat discrepancy, while men showed more discrepancy between actual and ideal muscularity than women. In regression analyses, sex was the only significant predictor of muscularity discrepancy, while disordered eating attitudes were a positive, and positive perfectionism was a negative predictor of body fat discrepancy.
This study showed that while muscularity dissatisfaction is linked to the male sex, body fat dissatisfaction is not related to sex but to psychological variables of disordered eating attitudes and positive perfectionism in a population of youths that may be above average when it comes to physical activity.
Dilated cardiomyopathy is one of the important diseases in dogs and humans. The second most common cause of heart failure in dogs is idiopathic dilated cardiomyopathy (iDCM), which results in heart ...failure or sudden cardiac death due to arrhythmia. This study aimed to determine changes in the plasma metabolome of dogs with iDCM compared to healthy dogs. For that purpose, a multiplatform mass-spectrometry-based approach was used. In this study, we included two groups of dogs: 12 dogs with iDCM and 8 healthy dogs. A total of 272 metabolites were detected in the plasma samples of dogs by combining three approaches but four MS-based platforms (GC-MS, LC-MS (untargeted), LC-MS (targeted), and FIA-MS (targeted) methods). Our findings demonstrated changes in the canine plasma metabolome involved in the development of iDCM, including the different concentrations of amino acids, biogenic amines, acylcarnitines, triglycerides and diglycerides, sphingomyelins, and organic acids. The results of this study will enable the detection and monitoring of pathophysiological mechanisms involved in the development of iDCM in the future.
Canine babesiosis is an important tick-borne disease worldwide, caused by parasites of the
genus. Although the disease process primarily affects erythrocytes, it may also have multisystemic ...consequences. The goal of this study was to explore and characterize the serum metabolome, by identifying potential metabolites and metabolic pathways in dogs naturally infected with
using liquid and gas chromatography coupled to mass spectrometry. The study included 12 dogs naturally infected with
and 12 healthy dogs. By combining three different analytical platforms using untargeted and targeted approaches, 295 metabolites were detected. The untargeted ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) metabolomics approach identified 64 metabolites, the targeted UHPLC-MS/MS metabolomics approach identified 205 metabolites, and the GC-MS metabolomics approach identified 26 metabolites. Biological functions of differentially abundant metabolites indicate the involvement of various pathways in canine babesiosis including the following: glutathione metabolism; alanine, aspartate, and glutamate metabolism; glyoxylate and dicarboxylate metabolism; cysteine and methionine metabolism; and phenylalanine, tyrosine, and tryptophan biosynthesis. This study confirmed that host-pathogen interactions could be studied by metabolomics to assess chemical changes in the host, such that the differences in serum metabolome between dogs with
infection and healthy dogs can be detected with liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS) methods. Our study provides novel insight into pathophysiological mechanisms of
infection.
This study aimed to determine the associations between the self-reported sleep duration and self-rated health in young adults.
In this cross-sectional study, participants were 689 young adults (mean ...age 20 ± 1.35 years, 49.8% female). Sleep duration and self-rated health, as the main outcome of interest, were measured as self-reported. As potential covariates, we included sex, age, smoking status, alcohol consumption, physical activity, sedentary behavior, psychological distress, and body mass index.
Approximately 30% of participants slept 7-8 hours, 17.4% were short sleepers (categories < 6 hours and 6-7 hours), and 53.9% were long sleepers (categories 8-10 hours and > 10 hours of sleep). In an unadjusted model, compared with the reference category (7-8 hours of sleep), those who slept < 6 hours (odds ratio 0.20; 95% confidence interval 0.08 to 0.48) and between 6-7 hours (odds ratio 0.43; 95% confidence interval 0.26 to 0.69) were less likely to have good self-rated health. In an adjusted model, short (< 7 hours) and long sleep (> 10 hours) were both associated with poor self-rated health.
Our results suggest that both short (< 7 hours) and long (> 10 hours) sleepers have lower odds of having good self-rated health after adjusting for potential covariates. Health professionals should pay more attention to young adults, who have both short and long period of sleep, in order to prevent health problems and potential acute or chronic diseases.
Canine babesiosis caused by the intraerythrocytic protozoan parasite Babesia canis is a tick-borne disease characterized by a host response that involves both cellular and humoral immunity. This ...study focuses on the secretion of cytokines Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), Keratinocyte Chemotactic-like (KC-like), Interleukins (IL)-2, IL-7, IL-8, IL-10, IL-15, IL-18 and Monocyte Chemotactic Protein-1 (MCP-1) in babesiosis caused by Babesia canis upon treatment with Imizol®. We assessed time dependent changes in cytokine levels and tested whether these changes correlate with pathogenesis of the disease. Sixteen healthy dogs and 31 dogs infected with Babesia canis, of which 18 showed complications, were treated with Imizol®. One dog died during the study (3.2%). Longitudinal study was perfomed by monitoring dogs at the first day of presentation (day 1) and 6 days later (day 7). Our results show that higher MCP-1 levels on day 1 are positively associated with the occurrence of complications, (complicated vs. uncomplicated; p = 0.00016). A similar pattern was observed for KC-like on day 1 (p = 0.0326) and day 7 (p = 0.044). Moreover, babesiosis caused by B. canis produced a steady increase in IL-8 levels with a moderate to strong negative correlation with erythrocyte counts and hematocrit in uncomplicated diseased dogs only (Spearman's rank correlation coefficient rs = -0.582 and rs = -0.598 respectively). Like for MCP-1, KC-like levels also differed in complicated and uncomplicated diseased dogs on day 1 (p = 0.03236) and day 7 (p = 0.044). Furthermore, KC-like levels were strongly correlated with IL-8 levels (rs = 0.663-0.7) and non-segmented neutrophil counts (rs = 0.572-0.732) in both diseased groups. Analysis of ROC suggests the use of serum levels of MCP-1 and IL-7 as predictors of the occurrence of complications with an AUC of 0.906 and 0.896 respectively and linear combinations of MCP-1, KC-Like, IL-7 and GM-CSF with values up to AUC = 0.983. Cytokine cluster analysis presented in this study can contribute to a better understanding of the pathogenesis of babesiosis and serve as a prognostic tool for the early detection of cases with highest likelihood of developing complications. Overall, our studies show that infection by B. canis elicits a cytokine pattern that is distinct from that observed with B. rossi, and that some of the inflammatory mediators can be useful to predict complications. Our results also suggest targets for the development of novel therapeutic strategies in babesiosis caused by B. canis.
Canine Babesiosis: Where Do We Stand? Petra, Bilić; Josipa, Kuleš; Renata, Barić Rafaj ...
Acta veterinaria,
06/2018, Letnik:
68, Številka:
2
Journal Article
Recenzirano
Odprti dostop
Canine babesiosis is a tick-borne disease caused by protozoal haemoparasites of different
species. Babesiosis is one of the most important globally extended and quickly spreading tick-borne ...infections of dogs. This comprehensive review gives an in-depth overview of
species currently identified in dogs together with relevant vector tick species and their geographical distribution, life cycle and transmission of parasite. The main mechanisms in the pathogenesis of babesiosis are described and elucidated by recent literature overview. As
infection causes a disease with very variable clinical manifestations, special attention is given to clinical signs, laboratory features and clinicopathological findings. The diagnosis of canine babesiosis by microscopy, serological and molecular methods is reviewed, together with recent advances in mass spectrometry based assays. Accurate detection and species recognition are important for the selection of the appropriate therapy, monitoring and prediction of the outcome of the disease. Finally, guidelines for the treatment and prevention of canine babesiosis are given.
Purpose: Researchers have extensively documented the cardiovascular and metabolic demands for sports participation. To date, researchers have ignored the same requirements of competitor’s parents. ...Hence, our purpose was to document parent cardiovascular and metabolic responses to watching their child compete while also paying particular attention to their thoughts before and after the competition. Achievement Goal Theory (AGT) drove interpretation of parent thoughts. Materials: Parents wore a device, made by Firstbeat Technologies, which continuously monitored heart rate. The parents wore the device the night before the competition to be acclimated to the technology and during the event until later in the day. Parents also completed two open-ended questions, one before the tournament and one after the contest. Results: Before the contest, the dad expected that his son won the event (Croatian National Championships for juniors). Conversely, the mother’s expectations centered more on her son’s enjoyment and competing to the best of his abilities. Parents had differing cardiovascular and energy requirement responses to watching their son compete. In addition, post-competition reflections differed as the father expressed disappointment whereas the mother expressed sadness. Conclusions: The data presented are unique and a first in the sports literature. The parents varied in the intensity of their cardiovascular responses and calories burned while watching their son compete. The father’s cardiovascular response over the course of watching was that of an aerobic workout. Whether this pattern is unique or universal are a critical research question. Last, AGT appears relevant when assessing the parent’s expectations.
Background and Purpose: Yeast derivative mannan oligosaccharide (MOS) and zeolite clinoptilolite (CPL) well known nutritional supplements acting as either prebiotic or immunobiotic, respectively, in ...animal husbandry. The aim of this study was to investigate whether or not these agents referred to as potential alternatives to antibiotics may positively influence systemic immune parameters of weaned pigs without negatively affecting their hematological, serum biochemical and gut histological homeostasis.Materials and Methods: Sixty pigs from a commercial farm were divided into three groups comprising 20 pigs each and treated at 4 weeks of age as follows: controls received standard weaner diet, whereas diet for principals was supplemented with 0.2% of MOS or 0.5% of CPL. The experiment was conducted throughout 35 days and at either Day 7 or Day 35 intervals starting at Day 0 before the treatments hematological, serum biochemical and intestinal histopathological parameters were monitored, respectively.Results: Pigs fed CPL supplement had lower proportion of lymphocytes (P<0.05), but higher proportions of neutrophils and eosinophils (P<0.05) at Day 21. Neither MOS nor CPL affected values of hematological parameters. Serum levels of hepatic enzymes in pigs fed CPL supplemen, with exception of lower value of creatinine kinase (CK) at Day 35 (P<0.01) were not changed. These pigs had lower level of total proteins (P<0.05) at Day 28, but higher levels of urea (P<0.05) and creatinine (P<0.01) at Day 35. Generally, principal pigs had milder damages of villi, similar infiltration of lymphoid/myeloid cells within jejunal/ileal lamina propria and follicular hyperplasia in mesenterc lymph node, but more extensive proliferation within Peyer’s patches.Conclusions: MOS did not affect any of monitored parameters, and CPL only sporadically induced lymphopaenia and granulocytosis, decrease of CK and total proteins and increase of urea and creatinine levels, indicating that the agents were not associated with any harmful side effects on monitored blood and gut parameters and impairment in general health status of pigs.
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