This study examined associations between cumulative training load, travel demands and recovery days with athlete-reported outcome measures (AROMs) and countermovement jump (CMJ) performance in ...professional basketball. Retrospective analysis was performed on data collected from 23 players (mean±SD: age = 24.7±2.5 years, height = 198.3±7.6 cm, body mass = 98.1±9.0 kg, wingspan = 206.8±8.4 cm) from 2018–2020 in the National Basketball Association G-League. Linear mixed models were used to describe variation in AROMs and CMJ data in relation to cumulative training load (previous 3- and 10-days), hours travelled (previous 3- and 10-day), days away from the team’s home city, recovery days (i.e., no travel/minimal on-court activity) and individual factors (e.g., age, fatigue, soreness). Cumulative 3-day training load had negative associations with fatigue, soreness, and sleep, while increased recovery days were associated with improved soreness scores. Increases in hours travelled and days spent away from home over 10 days were associated with increased sleep quality and duration. Cumulative training load over 3 and 10 days, hours travelled and days away from home city were all associated with changes in CMJ performance during the eccentric phase. The interaction of on-court and travel related stressors combined with individual factors is complex, meaning that multiple athletes response measures are needed to understand fatigue and recovery cycles. Our findings support the utility of the response measures presented (i.e., CMJ and AROMs), but this is not an exhaustive battery and practitioners should consider what measures may best inform training periodization within the context of their environment/sport.
ABSTRACT
Measurements of the Hubble constant, H0, from the cosmic distance ladder are currently in tension with the value inferred from Planck observations of the cosmic microwave background (CMB) ...and other high-redshift data sets if a flat Λ cold dark matter (ΛCDM) cosmological model is assumed. One of the few promising theoretical resolutions of this tension is to invoke new physics that changes the sound horizon scale in the early Universe; this can bring CMB and baryon acoustic oscillations (BAO) constraints on H0 into better agreement with local measurements. In this paper, we discuss how a measurement of the Hubble constant can be made from the CMB without using information from the sound horizon scale, rs. In particular, we show how measurements of the CMB lensing power spectrum can place interesting constraints on H0 when combined with measurements of either supernovae or galaxy weak lensing, which constrain the matter density parameter. The constraints arise from the sensitivity of the CMB lensing power spectrum to the horizon scale at matter–radiation equality (in projection); this scale could have a different dependence on new physics than the sound horizon. From an analysis of current CMB lensing data from Planck and Pantheon supernovae with conservative external priors, we derive an rs-independent constraint of $H_0 = 73.5\pm 5.3\, {\rm km}\,{\rm s}^{-1}\,{\rm Mpc}^{-1}$. Forecasts for future CMB surveys indicate that improving constraints beyond an error of $\sigma (H_0) = 3\, {\rm km}\,{\rm s}^{-1}\,{\rm Mpc}^{-1}$ will be difficult with CMB lensing, although applying similar methods to the galaxy power spectrum may allow for further improvements.
Summary Background Anorexia nervosa is characterised by a chronic course that is refractory to treatment in many patients and has one of the highest mortality rates of any psychiatric disorder. Deep ...brain stimulation (DBS) has been applied to circuit-based neuropsychiatric diseases, such as Parkinson's disease and major depression, with promising results. We aimed to assess the safety of DBS to modulate the activity of limbic circuits and to examine how this might affect the clinical features of anorexia nervosa. Methods We did a phase 1, prospective trial of subcallosal cingulate DBS in six patients with chronic, severe, and treatment-refractory anorexia nervosa. Eligible patients were aged 20–60 years, had been diagnosed with restricting or binge-purging anorexia nervosa, and showed evidence of chronicity or treatment resistance. Patients underwent medical optimisation preoperatively and had baseline body-mass index (BMI), psychometric, and neuroimaging investigations, followed by implantation of electrodes and pulse generators for continuous delivery of electrical stimulation. Patients were followed up for 9 months after DBS activation, and the primary outcome of adverse events associated with surgery or stimulation was monitored at every follow-up visit. Repeat psychometric assessments, BMI measurements, and neuroimaging investigations were also done at various intervals. This trial is registered with ClinicalTrials.gov , number NCT01476540. Findings DBS was associated with several adverse events, only one of which (seizure during programming, roughly 2 weeks after surgery) was serious. Other related adverse events were panic attack during surgery, nausea, air embolus, and pain. After 9 months, three of the six patients had achieved and maintained a BMI greater than their historical baselines. DBS was associated with improvements in mood, anxiety, affective regulation, and anorexia nervosa-related obsessions and compulsions in four patients and with improvements in quality of life in three patients after 6 months of stimulation. These clinical benefits were accompanied by changes in cerebral glucose metabolism (seen in a comparison of composite PET scans at baseline and 6 months) that were consistent with a reversal of the abnormalities seen in the anterior cingulate, insula, and parietal lobe in the disorder. Interpretation Subcallosal cingulate DBS seems to be generally safe in this sample of patients with chronic and treatment-refractory anorexia nervosa. Funding Klarman Family Foundation Grants Program in Eating Disorders Research and Canadian Institutes of Health Research.
At the start of a venture, most entrepreneurs wear many hats. However, entrepreneurs often cannot remain involved in every aspect of the venture process, and so they face important decisions about ...which roles to give up, which roles to retain, and which new roles to adopt. For many, this process is particularly difficult as roles represent more than just something entrepreneurs do but also an important part of who they are (role identities). Through an inductive field study, this research reveals how and why entrepreneurs add, subtract, or retain roles. We find three mechanisms—perceiving the entrepreneur as someone who ‘gives up the hats,’ discovering new meaning (new role identities) within the venture, and role identity imprinting—lead to a narrowing of one's role set, which ultimately influences venture growth.
•We provide three mechanisms that explain how and why entrepreneurs ‘give up the hats’ in their ventures.•We show the relationship between entrepreneurs' role-related actions and venture growth.•We extend entrepreneurial role identity by showing entrepreneurs have two different perceptions of what it means to 'be an entrepreneur.’•We offer explanations for how entrepreneurs negotiate and discover role identities within the venture.•We discover a new theoretical process of imprinting—role identity imprinting.
ABSTRACT
The search for cosmic polarization rotation or birefringence in the cosmic microwave background (CMB) is well motivated because it can provide powerful constraints on parity-violating new ...physics, such as axion-like particles. In this paper, we point out that since the CMB polarization is produced at two very different redshifts – it is generated at both reionization and recombination – new parity-violating physics can generically rotate the polarization signals from these different sources by different amounts. We explore two implications of this. First, measurements of CMB birefringence are challenging because the effect is degenerate with a miscalibration of CMB polarization angles; however, by taking the difference of the reionization and recombination birefringence angles (measured from different CMB angular scales), we can obtain a cosmological signal that is immune to instrumental angle miscalibration. Secondly, we note that the combination with other methods for probing birefringence can give tomographic information, constraining the redshift origin of any physics producing birefringence. We forecast that the difference of the reionization and recombination birefringence angles can be competitively determined to within ∼0.05 deg for future CMB satellites such as LiteBIRD. Although much further work is needed, we argue that foreground mitigation for this measurement should be less challenging than for inflationary B-mode searches on similar scales due to larger signals and lower foregrounds.
Extant research suggests that entrepreneurs’ identities influence the venture creation process. However, we know little about how the “hats” that entrepreneurs wear (i.e., their different role ...identities) influence how entrepreneurs think about—and select—opportunities. Employing verbal protocol and content analysis techniques, we show that, depending on the role identity assumed, entrepreneurs attend to different opportunity features and make different decisions with regard to opportunity consideration and selection. As a result, role identity has an important situated influence on entrepreneurs’ cognition, which may significantly affect the pattern of growth and pursuit of their new ventures.
The landforms of northern Gale crater on Mars expose thick sequences of sedimentary rocks. Based on images obtained by the Curiosity rover, we interpret these outcrops as evidence for past fluvial, ...deltaic, and lacustrine environments. Degradation of the crater wall and rim probably supplied these sediments, which advanced inward from the wall, infilling both the crater and an internal lake basin to a thickness of at least 75 meters. This intracrater lake system probably existed intermittently for thousands to millions of years, implying a relatively wet climate that supplied moisture to the crater rim and transported sediment via streams into the lake basin. The deposits in Gale crater were then exhumed, probably by wind-driven erosion, creating Aeolis Mons (Mount Sharp).
ABSTRACT
The early dark energy (EDE) solution to the Hubble tension comes at the cost of an increased clustering amplitude that has been argued to worsen the fit to galaxy clustering data. We explore ...whether freeing the total neutrino mass Mν, which can suppress small-scale structure growth, improves EDE’s fit to galaxy clustering. Using Planck Cosmic Microwave Background and BOSS galaxy clustering data, a Bayesian analysis shows that freeing Mν does not appreciably increase the inferred EDE fraction fEDE: we find the 95 per cent C.L. upper limits fEDE < 0.092 and $M_{\nu }\lt 0.15\, {\rm eV}$. Similarly, in a frequentist profile likelihood setting (where our results support previous findings that prior volume effects are important), we find that the baseline EDE model (with $M_{\nu }=0.06\, {\rm eV}$) provides the overall best fit. For instance, compared to baseline EDE, a model with $M_\nu =0.24\, {\rm eV}$ maintains the same H0(km/s/Mpc) = (70.08, 70.11, respectively) whilst decreasing S8 = (0.837, 0.826) to the ΛCDM level, but worsening the fit significantly by Δχ2 = 7.5. For the datasets used, these results are driven not by the clustering amplitude, but by background modifications to the late-time expansion rate due to massive neutrinos, which worsen the fit to measurements of the BAO scale.
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