One major challenge for the legacy measurements at the LHC is that the likelihood function is not tractable when the collected data is high-dimensional and the detector response has to be modeled. We ...review how different analysis strategies solve this issue, including the traditional histogram approach used in most particle physics analyses, the Matrix Element Method, Optimal Observables, and modern techniques based on neural density estimation. We then discuss powerful new inference methods that use a combination of matrix element information and machine learning to accurately estimate the likelihood function. The MadMiner package automates all necessary data-processing steps. In first studies we find that these new techniques have the potential to substantially improve the sensitivity of the LHC legacy measurements.
A Monte Carlo event generator is implemented for a two-Higgs-doublet model with maximal CP symmetry, the MCPM. The model contains five physical Higgs bosons; the
ρ
′, behaving similarly to the ...standard-model Higgs boson, two extra neutral bosons
h
′ and
h
″, and a charged pair
H
±
. The special feature of the MCPM is that, concerning the Yukawa couplings, the bosons
h
′,
h
″ and
H
±
couple directly only to the second-generation fermions but with strengths given by the third-generation-fermion masses. Our event generator allows the simulation of the Drell–Yan-type production processes of
h
′,
h
″ and
H
±
in proton–proton collisions at LHC energies. Also the subsequent leptonic decays of these bosons into the
μ
+
μ
−
,
μ
+
ν
μ
and
channels are studied as well as the dominant background processes. We estimate the integrated luminosities needed in
pp
collisions at center-of-mass energies of 8 and 14 TeV for significant observations of the Higgs bosons
h
′,
h
″ and
H
±
in these muonic channels.
Intercell interference is the major limiting factor in wireless multicell networks. Recently, it has been shown that significant performance gains can be achieved by cooperation among base stations. ...Different degrees of cooperation are possible. In this paper, cooperation in the form of intercell interference management is considered. The base stations are equipped with multiple antennas, while the mobile terminals only have a single antenna. The base stations jointly coordinate beamforming and scheduling, and thus perform a weaker form of cooperation among base stations than suggested in recently proposed joint transmission techniques. The terminals treat intercell interference as noise. The corresponding resource allocation problem is cast as a utility maximization problem, which includes common performance objectives such as the arithmetic mean, the geometric mean, and the max-min operation of achievable user rates. The resulting utility maximization problem is a nonconvex optimization problem. After a suitable reformulation, the problem can be solved to global optimality using the framework of monotonic optimization. Although, the numerical complexity of the proposed method is exponential, the reformulation step leads to an optimization problem which only scales in the number of mobile terminals instead of the entire set of physical layer parameters. In essence, the proposed framework represents a powerful tool for computing benchmarks for certain scenarios and utility functions under jointly optimal beamforming and scheduling.
We design Tomlinson-Harashima precoding for decentralized receivers and frequency-selective channels based on the minimum mean square error criterion, where the feedforward filter is restricted to ...have finite length. Contrary to most other publications on Tomlinson-Harashima precoding which rely on solutions for decision feedback equalization to find the corresponding precoding filters in a heuristic manner, we deduce the optimization for Tomlinson-Harashima precoding from the optimization for the linear minimum mean square error transmit filter. Thereby, we include the precoding order explicitly in the problem formulation and thus obtain the precoding filter solutions, together with the algorithms to compute the latency time, i.e., the time difference between application of the precoder at the transmitter and detection at the receiver and the precoding order from a single optimization. Since the algorithm for THP filter computation resulting from the optimization has a high computational complexity, we present an alternative algorithm to compute the Tomlinson-Harashima precoding filters based on a Cholesky factorization with symmetric permutation, resulting in an order of complexity that is the same as for the computation of the linear transmit filters. The simulations reveal that the latency time optimization can be omitted without performance degradation for most practical channel models, i.e., the latency time can be chosen to be the order of the feedforward filter
A Monte Carlo event generator is implemented for a two-Higgs-doublet model with maximal CP symmetry, the MCPM. The model contains five physical Higgs bosons; the ρ', behaving similarly to the ...standard-model Higgs boson, two extra neutral bosons h and h", and a charged pair H.sup.±. The special feature of the MCPM is that, concerning the Yukawa couplings, the bosons h', h" and H.sup.+ or - couple directly only to the second-generation fermions but with strengths given by the third-generation-fermion masses. Our event generator allows the simulation of the Drell-Yan-type production processes of hh, h" and H.sup.± in proton-proton collisions at LHC energies. Also the subsequent leptonic decays of these bosons into the μ.sup.+μ.sup.-, μ.sup.+v.sub.μ and μ.sup.- bar.v.sub.μ channels are studied as well as the dominant background processes. We estimate the integrated luminosities needed in pp collisions at center-of-mass energies of 8 and 14 TeV for significant observations of the Higgs bosons hh, h" and H.sup.± in these muonic channels.
A Monte Carlo event generator is constructed for a two-Higgs-doublet model with maximal CP symmetry, the MCPM. The model contains five physical Higgs bosons; the \(\rho'\), behaving similarly to the ...standard-model Higgs boson, two extra neutral bosons \(h'\) and \(h"\), and a charged pair \(H^\pm\). The special feature of the MCPM is that, concerning the Yukawa couplings, the bosons \(h'\), \(h"\) and \(H^\pm\) couple directly only to the second generation fermions but with strengths given by the third-generation-fermion masses. Our event generator allows the simulation of the Drell-Yan-type production processes of \(h'\), \(h"\) and \(H^\pm\) in proton-proton collisions at LHC energies. Also the subsequent leptonic decays of these bosons into the \(\mu^+ \mu^-\), \(\mu^+ \nu_\mu\) and \(\mu^- \bar \nu_\mu\) channels are studied as well as the dominant background processes. We estimate the integrated luminosities needed in \(p p\) collisions at center-of-mass energies of 8 TeV and 14 TeV for significant observations of the Higgs bosons \(h'\), \(h"\) and \(H^\pm\) in these muonic channels.
We present the activities of the 'New Physics' working group for the 'Physics at TeV Colliders' workshop (Les Houches, France, 1-19 June, 2015). Our report includes new physics studies connected with ...the Higgs boson and its properties, direct search strategies, reinterpretation of the LHC results in the building of viable models and new computational tool developments. Important signatures for searches for natural new physics at the LHC and new assessments of the interplay between direct dark matter searches and the LHC are also considered.
Recently tissue polypeptide specific antigen (TPS), a cytokeratin 18 marker, was described to be discriminative between cancer of the prostate (CaP) and benign prostatic hyperplasia (BPH). Cyfra ...8/18, a marker which recognizes both cytokeratin 8 and 18 fragments, is thought to improve sensitivity and specificity of TPS. In our study we investigated the ability of the TPS and cyfra 8/18 serum concentration to discriminate between patients with clinically localized CaP and BPH.
Serum levels of TPS and Cyfra 8/18 were determined in patients with untreated CaP (pT1-3pNoMo: n = 11) and BPH (n = 22). The TPS and the Cyfra 8/18 concentrations were correlated to the prostate specific antigen (PSA) serum concentration.
Median TPS concentration was 45.3 U/L in CaP-patients and 54.8 U/L in BPH-patients. This difference is statistically not significant (p = 0.2). Median Cyfra 8/18 level was 0.64 ng/mL in CaP-patients and 0.57 ng/mL in BPH-patients. This difference is statistically not significant (p = 0.91). Furthermore no correlation with PSA levels could be established (TPS: r = -0.13; Cyfra 8/18: r = 0.17).
In contrast to recent reports we found both cytokeratin markers, TPS as well as Cyfra 8/18, to be non-discriminative parameters in CaP and BPH.
Bat rabies in Lower Saxony Seidler M; Brehmer H. J; Pott B ...
Berliner und Münchener tierärztliche Wochenschrift,
06/1987, Letnik:
100
Journal Article
PDF
