Sandra Bruce is the Nurse Education Program Manager, Air Force Personnel Center, Joint Base San Antonio-Randolph in Texas, and is responsible for the Air Force Continuing Nursing Education program ...and facilitation of selection boards for graduate education and fellowship programs. She served as editor for the third and fourth editions of the Association for Nursing Professional Development (ANPD) Core Curriculums for Nursing Professional Development. Sandy previously served as the Education Consultant to the Air Force Surgeon General for Nursing Education programs for over 3,000 Air Force Nurse Corps members. She received her BSN from Mercy College of Detroit in 1976 and entered the Air Force in 1982. The Air Force sponsored her Master's Degree in Nursing as a Clinical Nurse Specialist.
School closures in Indonesia during the COVID-19 pandemic have left 45.5 million school students and 3.1 million teachers dependent on online teaching and learning. Online teaching and learning are ...an unprecedented experience for most teachers and students; consequently, they have a limited experience with it. This paper examines the views of secondary school mathematics teachers on E-learning implementation barriers during the COVID-19 pandemic at four barrier levels, namely teacher, school, curriculum and student. Furthermore, it assesses the relationship between barrier levels with teachers’ demographic background. Data was collected through an online questionnaire, involving 159 participants from lower and upper secondary schools in Indonesia. The findings of this study suggest that student level barrier had the highest impact on e-learning use. In addition, the student level barrier showed strong positive correlation with the school level barrier and curriculum level barrier. The study showed that teachers’ backgrounds had no impact on the level of barriers. This study stimulates further discussion on the way to overcome e-learning barriers whilst simultaneously maximizing benefits of E-learning during this pandemic and beyond it by highlighting the importance of students’ voices.
An intense laser pulse focused onto a plasma can excite nonlinear plasma waves. Under appropriate conditions, electrons from the background plasma are trapped in the plasma wave and accelerated to ...ultra-relativistic velocities. This scheme is called a laser wakefield accelerator. In this work, we present results from a laser wakefield acceleration experiment using a petawatt-class laser to excite the wakefields as well as nanoparticles to assist the injection of electrons into the accelerating phase of the wakefields. We find that a 10-cm-long, nanoparticle-assisted laser wakefield accelerator can generate 340 pC, 10 ± 1.86 GeV electron bunches with a 3.4 GeV rms convolved energy spread and a 0.9 mrad rms divergence. It can also produce bunches with lower energies in the 4–6 GeV range.
Working on What Works (WOWW) is a solution-oriented classroom management intervention. Following an outline of Berg and Shilts' WOWW programme in the United States, this paper reviews and evaluates ...WOWW, which has been implemented as a classroom intervention strategy in a Scottish local authority since 2007. Qualitative analysis of the comments of children and teachers from 12 classes suggests that WOWW may be an effective classroom management intervention that helps teachers to feel more confident and also produces tangible improvements in the way children work and behave. Children also report positive differences in how they perceive their class and teacher.
In an interview, Sandra Bruce, FACHE, president and CEO at Resurrection Health Care and Provena Health, talked about her award as one of the Top 25 Women in Healthcare, and Catholic healthcare ...identity. Bruce said assessing candidates on education and experience alone is not enough. She tries to determine how open candidates are to others' perspectives and opinions and how skilled they are in negotiation and conflict management. She also like to learn about their creative skills, their drive, and the softer issues around personality. When filling a top executive position, she looks to see if the people under consideration are also committed to that goal. The identity of Catholic healthcare is rooted in several different areas. First is the significant respect for human life. Second is the great and deep respect for individuals and their needs and directives. Third, Catholic healthcare focuses on holistic care-treating mind, body, and spirit.
Leishmania major, an intracellular parasitic protozoon that infects, differentiates and replicates within macrophages, expresses two closely related MIF-like proteins. To ascertain the roles and ...potential differences of these two
Leishmania proteins, recombinant
L. major MIF1 and MIF2 have been produced and the structures resolved by X-ray crystallography. Each has a trimeric ring architecture similar to mammalian MIF, but with some structurally distinct features. LmjMIF1, but not LmjMIF2, has tautomerase activity. LmjMIF2 is found in all life cycle stages whereas LmjMIF1 is found exclusively in amastigotes, the intracellular stage responsible for mammalian disease. The findings are consistent with parasite MIFs modulating or circumventing the host macrophage response, thereby promoting parasite survival, but suggest the LmjMIFs have potentially different biological roles. Analysis of the
Leishmania braziliensis genome showed that this species lacks both
MIF genes. Thus MIF is not a virulence factor in all species of
Leishmania.
Amino acid substitutions at several positions in the surface antigen (HBsAg) of hepatitis B virus (HBV) in natural isolates and the products of recombinant DNA molecules have identified important ...residues for cross-reaction with specific antibodies (anti-HBs) and the induction of antibodies with certain serological specificities. In a further group of mutants described here, cysteine residues in a region believed to be significant of the a epitope have been changed to serines. Of the three adjacent cysteine residues at positions 137, 138 and 139, mutation of either of the flanking residues reduced cross-reactivity with polyclonal anti-HBs, while alteration of the central residue was relatively well-tolerated. Mutation of cysteine 149 to serine or of glycine 145 to arginine (imitating naturally occurring mutants), lysine, or glutamatic acid all led to loss of cross-reactivity with polyclonal antisera.
Leishmania major
, an intracellular parasitic protozoon that infects, differentiates and replicates within macrophages, encodes two closely related MIF-like proteins, which have only ~20% amino acid ...identity with mammalian MIF. Recombinant
L. major
MIF1 and MIF2 have been expressed and the structures, resolved by X-ray crystallography, show a trimeric ring architecture similar to mammalian MIF but with some structurally distinct features. LmjMIF1, but not LmjMIF2, has tautomerase activity, indicating that the LmjMIFs have evolved potentially different biological roles. This is further demonstrated by the differential life cycle expression of the proteins. LmjMIF2 is found in all life cycle stages whereas LmjMIF1 is found exclusively in amastigotes, the intracellular stage responsible for mammalian disease. The findings are consistent with parasite MIFs modulating or circumventing the host macrophage response and thereby promoting parasite survival, however analysis of the
L. braziliensis
genome showed that this species lacks intact
MIF
genes - highlighting that MIF is not a virulence factor in all species of
Leishmania
.
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