ABSTRACT The origin and composition of ultra-high-energy cosmic rays (UHECRs) remain a mystery. The proton dip model describes their spectral shape in the energy range above 109 GeV by pair ...production and photohadronic interactions with the cosmic microwave background. The photohadronic interactions also produce cosmogenic neutrinos peaking around 109 GeV. We test whether this model is still viable in light of recent UHECR spectrum measurements from the Telescope Array experiment and upper limits on the cosmogenic neutrino flux from IceCube. While two-parameter fits have been already presented, we perform a full scan of the three main physical model parameters: source redshift evolution, injected proton maximal energy, and spectral index. We find qualitatively different conclusions compared to earlier two-parameter fits in the literature: a mild preference for a maximal energy cutoff at the sources instead of the Greisen-Zatsepin-Kuzmin cutoff, hard injection spectra, and strong source evolution. The predicted cosmogenic neutrino flux exceeds the IceCube limit for any parameter combination. As a result, the proton dip model is challenged at more than 95% C.L. This is strong evidence against this model independent of mass composition measurements.
Gamma-ray bursts (GRBs) are short-lived, luminous explosions at cosmological distances, thought to originate from relativistic jets launched at the deaths of massive stars. They are among the prime ...candidates to produce the observed cosmic rays at the highest energies. Recent neutrino data have, however, started to constrain this possibility in the simplest models with only one emission zone. In the classical theory of GRBs, it is expected that particles are accelerated at mildly relativistic shocks generated by the collisions of material ejected from a central engine. Here we consider neutrino and cosmic-ray emission from multiple emission regions since these internal collisions must occur at very different radii, from below the photosphere all the way out to the circumburst medium, as a consequence of the efficient dissipation of kinetic energy. We demonstrate that the different messengers originate from different collision radii, which means that multi-messenger observations open windows for revealing the evolving GRB outflows.
A
bstract
Neutrino interactions with protons and neutrons probe their deep structure and may reveal new physics. The higher the neutrino energy, the sharper the probe. So far, the neutrino-nucleon (
...νN
) cross section is known across neutrino energies from a few hundred MeV to a few PeV. Soon, ultra-high-energy (UHE) cosmic neutrinos, with energies above 100 PeV, could take us farther. So far, they have evaded discovery, but upcoming UHE neutrino telescopes endeavor to find them. We present the first detailed measurement forecasts of the UHE
νN
cross section, geared to IceCube-Gen2, one of the leading detectors under planning. We use state-of-the-art ingredients in every stage of our forecasts: in the UHE neutrino flux predictions, the neutrino propagation inside Earth, the emission of neutrino-induced radio signals in the detector, their propagation and detection, and the treatment of backgrounds. After 10 years, if at least a few tens of UHE neutrino-induced events are detected, IceCube-Gen2 could measure the
νN
cross section at center-of-mass energies of
s
≈
10–100 TeV for the first time, with a precision comparable to that of its theory prediction.
Respiratory failure complicates most critically ill patients with COVID-19 and is characterized by heterogeneous pulmonary parenchymal involvement, profound hypoxemia and pulmonary vascular injury. ...The high incidence of COVID-19 related respiratory failure has exposed critical shortages in the supply of mechanical ventilators, and providers with the necessary skills to treat. Traditional mass-produced ventilators rely on an internal compressor and mixer to moderate and control the gas mixture delivered to a patient. However, the current emergency has energized the pursuit of alternative designs, enabling greater flexibility in supply chain, manufacturing, storage, and maintenance considerations. To achieve this, we hypothesized that using the medical gasses and flow interruption strategy would allow for a high performance, low cost, functional ventilator. A low-cost ventilator designed and built-in accordance with the Emergency Use guidance from the US Food and Drug Administration (FDA) is presented wherein pressurized medical grade gases enter the ventilator and time limited flow interruption determines the ventilator rate and tidal volume. This simple strategy obviates the need for many components needed in traditional ventilators, thereby dramatically shortening the time from storage to clinical deployment, increasing reliability, while still providing life-saving ventilatory support. The overall design philosophy and its applicability in this new crisis is described, followed by both bench top and animal testing results used to confirm the precision, safety and reliability of this low cost and novel approach to mechanical ventilation. The ventilator meets and exceeds the critical requirements included in the FDA emergency use guidelines. The ventilator has received emergency use authorization from the FDA.
Gamma-ray bursts (GRBs) are promising as sources of neutrinos and cosmic rays. In the internal shock scenario, blobs of plasma emitted from a central engine collide within a relativistic jet and form ...shocks, leading to particle acceleration and emission. Motivated by present experimental constraints and sensitivities, we improve the predictions of particle emission by investigating time-dependent effects from multiple shocks. We produce synthetic light curves with different variability timescales that stem from properties of the central engine. For individual GRBs, qualitative conclusions about model parameters, neutrino production efficiency, and delays in high-energy gamma-rays can be deduced from inspection of the gamma-ray light curves. GRBs with fast time variability without additional prominent pulse structure tend to be efficient neutrino emitters, whereas GRBs with fast variability modulated by a broad pulse structure can be inefficient neutrino emitters and produce delayed high-energy gamma-ray signals. Our results can be applied to quantitative tests of the GRB origin of ultra-high-energy cosmic rays, and have the potential to impact current and future multi-messenger searches.