We report the measurement of the two-neutrino double-beta (
2
ν
β
β
) decay of
100
Mo to the ground state of
100
Ru using lithium molybdate (
Li
2
100
MoO
4
) scintillating bolometers. The detectors ...were developed for the CUPID-Mo program and operated at the EDELWEISS-III low background facility in the Modane underground laboratory (France). From a total exposure of 42.235 kg
×
day, the half-life of
100
Mo is determined to be
T
1
/
2
2
ν
=
7
.
12
-
0.14
+
0.18
(
stat
.
)
±
0.10
(
syst
.
)
×
10
18
years. This is the most accurate determination of the
2
ν
β
β
half-life of
100
Mo to date.
Three weeks after single‐lung transplantation for pulmonary fibrosis, a patient with high serum levels of de novo donor‐specific antibodies received high‐dose intravenous immunoglobulin (IVIG) ...infusion (scheduled dose: 2 g/kg on 2 days) to prevent antibody‐mediated rejection. Within the first hours after completion of infusions, he experienced acute lung injury involving the transplanted lung. Given the clinical evolution and the absence of an alternative diagnosis, transfusion‐related acute lung injury (TRALI) was diagnosed. The IVIG administered on each day was from the same batch. At day 110, because of an increase in the serum titers of donor‐specific antibodies, IVIG therapy was reintroduced but from a different batch, with excellent clinical tolerance. The lung injury was explored biologically, but no mechanism was revealed. Given the increasing use of IVIG in solid‐organ recipients, clinicians should be aware of possible TRALI after IVIG infusion.
The New IRAM KID Arrays 2 (NIKA2) consortium has just finished installing and commissioning a millimetre camera on the IRAM 30-m telescope. It is a dual-band camera operating with three ...frequency-multiplexed kilo-pixels arrays of lumped element kinetic inductance detectors (LEKID) cooled at 150 mK, designed to observe the intensity and polarisation of the sky at 260 and 150 GHz (1.15 and 2 mm). NIKA2 is today an IRAM resident instrument for millimetre astronomy, such as intracluster medium from intermediate to distant clusters and so for the follow-up of Planck satellite detected clusters, high redshift sources and quasars, early stages of star formation and nearby galaxies emission. We present an overview of the instrument performance as it has been evaluated at the end of the commissioning phase.
The energy-dispersive X-ray spectrometer (EDS or EDX) is a commonly used device to characterise the composition of investigated material in scanning and transmission electron microscopes (SEM and ...TEM). One major benefit compared to wavelength-dispersive X-ray spectrometers (WDS) is that EDS systems collect the entire spectrum simultaneously. Therefore, not only are all emitted characteristic X-ray lines in the spectrum, but also the complete bremsstrahlung distribution is included. It is possible to get information about the specimen even from this radiation, which is usually perceived more as a disturbing background. This is possible by using theoretical model knowledge about bremsstrahlung excitation and absorption in the specimen in comparison to the actual measured spectrum. The core aim of this investigation is to present a method for better bremsstrahlung fitting in unknown geometry cases by variation of the geometry parameters and to utilise this knowledge also for characteristic radiation evaluation. A method is described, which allows the parameterisation of the true X-ray absorption conditions during spectrum acquisition. An 'effective tilt' angle parameter is determined by evaluation of the bremsstrahlung shape of the measured SEM spectra. It is useful for bremsstrahlung background approximation, with exact calculations of the absorption edges below the characteristic peaks, required for P/B-ZAF model based quantification methods. It can even be used for ZAF based quantification models as a variable input parameter. The analytical results are then much more reliable for the different absorption effects from irregular specimen surfaces because the unknown absorption dependency is considered. Finally, the method is also applied for evaluation of TEM spectra. In this case, the real physical parameter optimisation is with sample thickness (mass thickness), which is influencing the emitted and measured spectrum due to different absorption with TEM measurements. The effects are in the very low energy part of the spectrum, and are much more visible with most recent windowless TEM detectors. The thickness of the sample can be determined in this way from the measured bremsstrahlung spectrum shape.
The lung in inflammatory bowel disease Camus, P; Colby, T V
European respiratory journal/The European respiratory journal
15, Številka:
1
Journal Article
Context. The Planck satellite was successfully launched on May 14th 2009. We have completed the pre-launch calibration measurements of the High Frequency Instrument (HFI) on board Planck and their ...processing. Aims. We present the results ot the pre-launch calibration of HFI in which we have multiple objectives. First, we determine instrumental parameters that cannot be measured in-flight and predict parameters that can. Second, we take the opportunity to operate and understand the instrument under a wide range of anticipated operating conditions. Finally, we estimate the performance of the instrument built. Methods. We obtained our pre-launch calibration results by characterising the component and subsystems, then by calibrating the focal plane at IAS (Orsay) in the Saturne simulator, and later from the tests at the satellite level carried out in the CSL (Liège) cryogenic vacuum chamber. We developed models to estimate the instrument pre-launch parameters when no measurement could be performed. Results. We reliably measure the Planck-HFI instrument characteristics and behaviour, and determine the flight nominal setting of all parameters. The expected in-flight performance exceeds the requirements and is close or superior to the goal specifications.
We analyze the cosmological constraints that Archeops (Benoît et al. 2003) places on adiabatic cold dark matter models with passive power-law initial fluctuations. Because its angular power spectrum ...has small bins in $\ell$ and large $\ell$ coverage down to COBE scales, Archeops provides a precise determination of the first acoustic peak in terms of position at multipole $l_{\rm peak}=220\pm 6$, height and width. An analysis of Archeops data in combination with other CMB datasets constrains the baryon content of the Universe, $\Omega_{\rm b}h^2= 0.022^{+0.003}_{-0.004}$, compatible with Big-Bang nucleosynthesis and with a similar accuracy. Using cosmological priors obtained from recent non–CMB data leads to yet tighter constraints on the total density, e.g. $\Omega_{\rm tot}=1.00^{+0.03}_{-0.02}$ using the HST determination of the Hubble constant. An excellent absolute calibration consistency is found between Archeops and other CMB experiments, as well as with the previously quoted best fit model. The spectral index n is measured to be $1.04^{+0.10}_{-0.12}$ when the optical depth to reionization, τ, is allowed to vary as a free parameter, and $0.96^{+0.03}_{-0.04}$ when τ is fixed to zero, both in good agreement with inflation.
We present a determination by the Archeops experiment of the angular power spectrum of the cosmic microwave background anisotropy in 16 bins over the multipole range $\ell=15{-}350$. Archeops was ...conceived as a precursor of the Planck HFI instrument by using the same optical design and the same technology for the detectors and their cooling. Archeops is a balloon–borne instrument consisting of a 1.5 m aperture diameter telescope and an array of 21 photometers maintained at $\sim 100$ mK that are operating in 4 frequency bands centered at 143, 217, 353 and 545 GHz. The data were taken during the Arctic night of February 7, 2002 after the instrument was launched by CNES from Esrange base (Sweden). The entire data cover ~30% of the sky. This first analysis was obtained with a small subset of the dataset using the most sensitive photometer in each CMB band (143 and 217 GHz) and 12.6% of the sky at galactic latitudes above 30 degrees where the foreground contamination is measured to be negligible. The large sky coverage and medium resolution (better than 15 arcmin) provide for the first time a high signal-to-noise ratio determination of the power spectrum over angular scales that include both the first acoustic peak and scales probed by COBE/DMR. With a binning of $\Delta \ell=7$ to 25 the error bars are dominated by sample variance for $\ell$ below 200. A companion paper details the cosmological implications.
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