B, D and K decays Buchalla, G.; Komatsubara, T. K.; Muheim, F. ...
European physical journal. C, Particles and fields (Print),
09/2008, Letnik:
57, Številka:
1-2
Journal Article, Conference Proceeding
Recenzirano
Odprti dostop
The present report documents the results of Working Group 2:
B
,
D
and
K
decays, of the workshop on Flavor in the Era of the LHC, held at CERN from November 2005 through March 2007.
With the advent ...of the LHC, we will be able to probe New Physics (NP) up to energy scales almost one order of magnitude larger than it has been possible with present accelerator facilities. While direct detection of new particles will be the main avenue to establish the presence of NP at the LHC, indirect searches will provide precious complementary information, since most probably it will not be possible to measure the full spectrum of new particles and their couplings through direct production. In particular, precision measurements and computations in the realm of flavor physics are expected to play a key role in constraining the unknown parameters of the Lagrangian of any NP model emerging from direct searches at the LHC.
The aim of Working Group 2 was twofold: on the one hand, to provide a coherent up-to-date picture of the status of flavor physics before the start of the LHC; on the other hand, to initiate activities on the path towards integrating information on NP from high-
p
T
and flavor data.
This report is organized as follows: in Sect. 1, we give an overview of NP models, focusing on a few examples that have been discussed in some detail during the workshop, with a short description of the available computational tools for flavor observables in NP models. Section 2 contains a concise discussion of the main theoretical problem in flavor physics: the evaluation of the relevant hadronic matrix elements for weak decays. Section 3 contains a detailed discussion of NP effects in a set of flavor observables that we identified as “benchmark channels” for NP searches. The experimental prospects for flavor physics at future facilities are discussed in Sect. 4. Finally, Sect. 5 contains some assessments on the work done at the workshop and the prospects for future developments.
The Legacy of Cornell Accelerators Tigner, M; Cassel, D.G
Annual review of nuclear and particle science,
10/2015, Letnik:
65, Številka:
1
Journal Article
Recenzirano
Odprti dostop
This is the story of a culture and its evolution and legacy. Beginning with the invention of the cyclotron at Berkeley, the path of further accelerator development at Cornell via the Los Alamos ...experience of the primary actors is described. The science done with the accelerators and on the accelerators and beams themselves is reviewed and brought up to the current time. The evolution of the user community and the sources of support for accelerators and science done with them are discussed at the appropriate places in the story.
Patient-physician covenant Crawshaw, R; Rogers, D E; Pellegrino, E D ...
JAMA : the journal of the American Medical Association,
1995-May-17, Letnik:
273, Številka:
19
Journal Article
The requirement that SUSY should solve the hierarchy problem without undue fine-tuning imposes severe constraints on the new supersymmetric states. With the MSSM spectrum and soft SUSY breaking ...originating from universal scalar and gaugino masses at the Grand Unification scale, we show that the low-fine-tuned regions fall into two classes that will require complementary collider and dark matter searches to explore in the near future. The first class has relatively light gluinos or squarks which should be found by the LHC in its first run. We identify the multijet plus
E
T
miss
signal as the optimal channel and determine the discovery potential in the first run. The second class has heavier gluinos and squarks but the LSP has a significant Higgsino component and should be seen by the next generation of direct dark matter detection experiments. The combined information from the 7 TeV LHC run and the next generation of direct detection experiments can test almost all of the CMSSM parameter space consistent with dark matter and EW constraints, corresponding to a fine-tuning not worse than 1:100. To cover the complete low-fine-tuned region by SUSY searches at the LHC will require running at the full 14 TeV CM energy; in addition it may be tested indirectly by Higgs searches covering the mass range below 120 GeV.
Abstract This article synthesizes the presentations and conclusions of an international symposium on Phase 1 oncology trials, palliative care, and ethics held in 2014. The purpose of the symposium ...was to discuss the intersection of three independent trends that unfolded in the past decade. First, large-scale reviews of hundreds of Phase I trials have indicated there is a relatively low risk of serious harm and some prospect of clinical benefit that can be meaningful to patients. Second, changes in the design and analysis of Phase I trials, the introduction of “targeted” investigational agents that are generally less toxic, and an increase in Phase I trials that combine two or more agents in a novel way have changed the conduct of these trials and decreased fears and apprehensions about participation. Third, the field of palliative care in cancer has expanded greatly, offering symptom management to late-stage cancer patients, and demonstrated that it is not mutually exclusive with disease-targeted therapies or clinical research. Opportunities for collaboration and further research at the intersection of Phase 1 oncology trials and palliative care are highlighted.
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