KASCADE and KASCADE-Grande were multi-detector installations to measure individual air showers of cosmic rays at ultra-high energy. Based on data sets measured by KASCADE and KASCADE-Grande, 90% C.L. ...upper limits to the flux of gamma-rays in the primary cosmic ray flux are determined in an energy range of eV. The analysis is performed by selecting air showers with a low muon content as expected for gamma-ray-induced showers compared to air showers induced by energetic nuclei. The best upper limit of the fraction of gamma-rays to the total cosmic ray flux is obtained at eV with . Translated to an absolute gamma-ray flux this sets constraints on some fundamental astrophysical models, such as the distance of sources for at least one of the IceCube neutrino excess models.
The ‘KASCADE Cosmic ray Data Centre’ is a web portal (
https://kcdc.ikp.kit.edu
), where the data of the astroparticle physics experiment KASCADE-Grande are made available for the interested public. ...The KASCADE experiment was a large-area detector for the measurement of high-energy cosmic rays via the detection of extensive air showers. The multi-detector installations KASCADE and its extension KASCADE-Grande stopped the active data acquisition in 2013 after more than 20 years of data taking. In several updates since our first release in 2013 with KCDC we provide the public measured and reconstructed parameters of more than 433 million air showers. In addition, KCDC provides meta data information and documentation to enable a user outside the community of experts to perform their own data analysis. Simulation data from three different high energy interaction models have been made available as well as a compilation of measured and published spectra from various experiments. In addition, detailed educational examples shall encourage high-school students and early stage researchers to learn about astroparticle physics, cosmic radiation as well as the handling of Big Data and about the sustainable and public provision of scientific data.
This randomized, controlled study aims to evaluate the tolerability and the efficacy of curcumin in overweight subjects affected from metabolic syndrome, with a focus on impaired glucose intolerance ...and android-type fat accumulation.
Forty-four subjects, selected among those who after 30 days of diet and intervention lifestyle have shown a weight loss < 2%, have been treated for further 30 days either with curcumin complexed with phosphatidylserine in phytosome form or with pure phosphatidylserine. Outcomes concerning anthropometric measurements and body composition were analyzed at enrollment and after 30 and 60 days.
Curcumin administration increased weight loss from 1.88 to 4.91%, enhanced percentage reduction of body fat (from 0.70 to 8.43%), increased waistline reduction (from 2.36 to 4.14%), improved hip circumference reduction from 0.74 to 2.51% and enhanced reduction of BMI (from 2.10 to 6.43%) (p < 0.01 for all comparisons). Phosphatidylserine did not show any statistical significant effect. Tolerability was very good for both treatments, and no drop-out was reported.
Although preliminary, our findings suggest that a bioavailable form of curcumin is well-tolerated and can positively influence weight management in overweight people.
It may be generalized that all Evolutionary Algorithms (EA) draw their strength from two sources: exploration and exploitation. Surprisingly, within the context of multiobjective (MO) optimization, ...the impact of fitness assignment on the exploration-exploitation balance has drawn little attention. The vast majority of multiobjective evolutionary algorithms (MOEAs) presented to date resort to Pareto dominance classification as a fitness assignment methodology. However, the proportion of Pareto optimal elements in a set P grows with the dimensionality of P. Therefore, when the number of objectives of a multiobjective problem (MOP) is large, Pareto dominance-based ranking procedures become ineffective in sorting out the quality of solutions. This paper investigates the potential of using preference order-based approach as an optimality criterion in the ranking stage of MOEAs. A ranking procedure that exploits the definition of preference ordering (PO) is proposed, along with two strategies that make different use of the conditions of efficiency provided, and it is compared with a more traditional Pareto dominance-based ranking scheme within the framework of NSGA-II. A series of extensive experiments is performed on seven widely applied test functions, namely, DTLZ1, DTLZ2, DTLZ3, DTLZ4, DTLZ5, DTLZ6, and DTLZ7, for up to eight objectives. The results are analyzed through a suite of five performance metrics and indicate that the ranking procedure based on PO enables NSGA-II to achieve better scalability properties compared with the standard ranking scheme and suggest that the proposed methodology could be successfully extended to other MOEAs
Aims. We investigate the extension of the very high-energy spectral tail of the Crab Pulsar at energies above 400 GeV. Methods. We analyzed ~320 h of good-quality Crab data obtained with the MAGIC ...telescope from February 2007 to April 2014. Results. We report the most energetic pulsed emission ever detected from the Crab Pulsar reaching up to 1.5 TeV. The pulse profile shows two narrow peaks synchronized with those measured in the GeV energy range. The spectra of the two peaks follow two different power-law functions from 70 GeV up to 1.5 TeV and connect smoothly with the spectra measured above 10 GeV by the Large Area Telescope (LAT) on board the Fermi satellite. When making a joint fit of the LAT and MAGIC data above 10 GeV the photon indices of the spectra differ by 0.5 ± 0.1. Conclusions. Using data from the MAGIC telescopes we measured the most energetic pulsed photons from a pulsar to date. Such TeV pulsed photons require a parent population of electrons with a Lorentz factor of at least 5 × 106. These results strongly suggest IC scattering off low-energy photons as the emission mechanism and a gamma-ray production region in the vicinity of the light cylinder.
► All-particle energy spectrum of cosmic rays between knee and ankle is not a single power law. ► Just above 1016eV the spectrum exhibits a hardening. ► Around 8×1016eV there is a knee-like feature ...in the spectrum.
The energy spectrum of cosmic rays between 1016eV and 1018eV, derived from measurements of the shower size (total number of charged particles) and the total muon number of extensive air showers by the KASCADE-Grande experiment, is described. The resulting all-particle energy spectrum exhibits strong hints for a hardening of the spectrum at approximately 2·1016eV and a significant steepening at ≈8·1016eV. These observations challenge the view that the spectrum is a single power law between knee and ankle. Possible scenarios generating such features are discussed in terms of astrophysical processes that may explain the transition region from galactic to extragalactic origin of cosmic rays.
The Cherenkov Telescope Array (CTA) represents the next generation of ground-based instruments for very-high-energy (VHE) gamma-ray astronomy, aimed at improving on the sensitivity of ...current-generation experiments by an order of magnitude and providing coverage over four decades of energy. The current CTA design consists of two arrays of tens of imaging atmospheric Cherenkov Telescopes, comprising Small, Medium and Large-Sized Telescopes, with one array located in each of the Northern and Southern Hemispheres. To study the effect of the site choice on the overall CTA performance and support the site evaluation process, detailed Monte Carlo simulations have been performed. These results show the impact of different site-related attributes such as altitude, night-sky background and local geomagnetic field on CTA performance for the observation of VHE gamma rays.
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