Energy dispersive x-ray spectroscopy in a transmission electron microscope is often the first method employed to characterize the composition of nanowires. Ideally, it should be accurate and ...sensitive down to fractions of an atomic percent, and quantification results are often reported as such. However, one can often get substantial errors in accuracy even though the precision is high: for nanowires it is common for the quantified V/III atomic ratios to differ noticeably from 1. Here we analyse the origin of this systematic error in accuracy for quantification of the composition of III-V nanowires. By varying the electron illumination direction, we find electron channelling to be the primary cause, being responsible for errors in quantified V/III atomic ratio of 50%. Knowing the source of the systematic errors is required for applying appropriate corrections. Lastly, we show how channelling effects can provide information on the crystallographic position of dopants.
The objectives of this study were to examine the independent and dependent associations of maternal and paternal age and risk of offspring autism spectrum disorders (ASD), with and without ...intellectual disability (ID).
The sample consisted of 417 303 Swedish children born 1984-2003. ASD case status (N = 4746) was ascertained using national and regional registers. Smoothing splines in generalized additive models were used to estimate associations of parental age with ASD.
Whereas advancing parental age increased the risk of child ASD, maternal age effects were non-linear and paternal age effects were linear. Compared with mothers at the median age 29 years, those <29 had similar risk, whereas risk increased after age 30, with an odds ratio (OR) of 1.75 95% (CI): 1.63-1.89 at ages 40-45. For fathers, compared with the median age of 32 years, the OR for ages 55-59 was 1.39 (1.29-1.50). The risk of ASD was greater for older mothers as compared with older fathers. For example, mothers aged 40-45 (≥97.2th percentile) had an estimated 18.63 (95% CI: 17.25-20.01) ASD cases per 1000 births, whereas fathers aged 55-59 (≥99.7th percentile) had 16.35 (95% CI: 15.11-17.58) ASD cases per 1000 births. In analyses stratified by co-parental age, increased risk due to advancing paternal age was evident only with mothers ≤35 years. In contrast, advancing maternal age increased risk regardless of paternal age. Advancing parental age was more strongly associated with ASD with ID, compared with ASD without ID.
We confirm prior findings that advancing parental age increases risk of ASD, particularly for ASD with ID, in a manner dependent on co-parental age. Although recent attention has emphasized the effects of older fathers on ASD risk, an increase of n years in maternal age has greater implications for ASD risk than a similar increase in paternal age.
We present the impact tests that preceded the most recent operational upgrades to the land surface model used in the National Centers for Environmental Prediction (NCEP) mesoscale Eta model, whose ...operational domain includes North America. These improvements consist of changes to the “Noah” land surface model (LSM) physics, most notable in the area of cold season processes. Results indicate improved performance in forecasting low‐level temperature and humidity, with improvements to (or without affecting) the overall performance of the Eta model quantitative precipitation scores and upper air verification statistics. Remaining issues that directly affect the Noah LSM performance in the Eta model include physical parameterizations of radiation and clouds, which affect the amount of available energy at the surface, and stable boundary layer and surface layer processes, which affect surface turbulent heat fluxes and ultimately the surface energy budget.
Objective
To evaluate how hysterectomy affects the prescription of analgesic, psychotropic and neuroactive drugs in women with endometriosis using population‐based nationwide registers.
Design
...Nationwide cohort study.
Setting
Swedish national registers, from 1 January 2009 to 31 December 2018.
Population
Women with benign disease undergoing a total hysterectomy during the 4‐year period of 2012–2015. Women with endometriosis (n = 1074) were identified and compared with women who did not have endometriosis (n = 10 890).
Methods
Prospectively collected data from two population‐based registers were linked: the Swedish National Quality Register of Gynaecological Surgery and the Swedish National Drug Register. Multivariate logistic regression was used as the main statistical method.
Main outcome measures
Changes in drug prescription over time for 3 years prior to and 3 years after hysterectomy.
Results
The frequency of prescription of analgesics was higher in women with endometriosis compared with women without endometriosis (OR 2.2, 95% CI 1.7–2.9). Among women with endometriosis, the prescription of analgesics (OR 1.0, 95% CI 0.8–1.2) did not decrease 3 years after hysterectomy compared with the 3 years prior to surgery. There was also a significantly higher rate of prescription of psychoactive (OR 1.6, 95% CI 1.4–2.0) and neuroactive drugs (OR 1.9, 95% CI 1.3–2.7) in the long term postoperatively.
Conclusions
In women undergoing hysterectomy, endometriosis was associated with a higher prescription rate of analgesics. In the endometriosis group the prescription of analgesic, psychoactive and neuroactive drugs did not decrease when comparing prescription rates for the 3 years prior to and the 3 years after surgery.
Tweetable
In women with endometriosis, the long‐term prescription of analgesics did not decrease after hysterectomy.
Tweetable
In women with endometriosis, the long‐term prescription of analgesics did not decrease after hysterectomy.
The Plumbing of Land Surface Models Best, M. J.; Abramowitz, G.; Johnson, H. R. ...
Journal of hydrometeorology,
06/2015, Letnik:
16, Številka:
3
Journal Article
Recenzirano
Odprti dostop
The Protocol for the Analysis of Land Surface Models (PALS) Land Surface Model Benchmarking Evaluation Project (PLUMBER) was designed to be a land surface model (LSM) benchmarking intercomparison. ...Unlike the traditional methods of LSM evaluation or comparison, benchmarking uses a fundamentally different approach in that it sets expectations of performance in a range of metrics a priori—before model simulations are performed. This can lead to very different conclusions about LSM performance. For this study, both simple physically basedmodels and empirical relationships were used as the benchmarks. Simulations were performed with 13 LSMs using atmospheric forcing for 20 sites, and then model performance relative to these benchmarks was examined. Results show that even for commonly used statistical metrics, the LSMs’ performance varies considerably when compared to the different benchmarks. All models outperform the simple physically based benchmarks, but for sensible heat flux the LSMs are themselves outperformed by an out-of-sample linear regression against downward shortwave radiation. While moisture information is clearly central to latent heat flux prediction, the LSMs are still outperformed by a three-variable nonlinear regression that uses instantaneous atmospheric humidity and temperature in addition to downward shortwave radiation. These results highlight the limitations of the prevailing paradigm of LSM evaluation that simply compares an LSM to observations and to other LSMs without a mechanism to objectively quantify the expectations of performance. The authors conclude that their results challenge the conceptual view of energy partitioning at the land surface.
Articulations of Capital Pickles, John; Smith, Adrian; Begg, Robert ...
2015, 2016, 2015-12-10, 2016-03-03
eBook
Articulations of Capital offers an accessible, grounded, yet theoretically- sophisticated account of the geographies of global production networks, value chains, and regional development in ...post-socialist Eastern and Central Europe. * Proposes a new theorization of global value chains as part of a conjunctural economic geography * Develops a set of conceptual and theoretical arguments concerning the regional embeddedness of global production * Draws on longitudinal empirical research from over 20 years in the Bulgarian and Slovakian apparel industries * Makes a major intervention into the debate over the economic geographies of European integration and EU enlargement
The daytime interaction of the land surface with the atmospheric boundary layer (ABL) is studied using a coupled one-dimensional (column) land surface–ABL model. This is an extension of earlier work ...that focused on modeling the ABL for 31 May 1978 at Cabauw, Netherlands; previously, it was found that coupled land–atmosphere tests using a simple land surface scheme did not accurately represent surface fluxes and coupled ABL development. Here, findings from that earlier study on ABL parameterization are utilized, and include a more sophisticated land surface scheme. This land surface scheme allows the land–atmosphere system to respond interactively with the ABL. Results indicate that incoupledland–atmosphere model runs, realistic daytime surface fluxes and atmospheric profiles are produced, even in the presence of ABL clouds (shallow cumulus). Subsequently, the role of soil moisture in the development of ABL clouds is explored in terms of a new relative humidity tendency equation at the ABL top where a number of processes and interactions are involved. Among other issues, it is shown that decreasing soil moisture may actually lead to an increase in ABL clouds in some cases.
We present the main results from the second model intercomparison within the GEWEX (Global Energy and Water cycle EXperiment) Atmospheric Boundary Layer Study (GABLS). The target is to examine the ...diurnal cycle over land in today’s numerical weather prediction and climate models for operational and research purposes. The set-up of the case is based on observations taken during the Cooperative Atmosphere-Surface Exchange Study-1999 (CASES-99), which was held in Kansas, USA in the early autumn with a strong diurnal cycle with no clouds present. The models are forced with a constant geostrophic wind, prescribed surface temperature and large-scale divergence. Results from 30 different model simulations and one large-eddy simulation (LES) are analyzed and compared with observations. Even though the surface temperature is prescribed, the models give variable near-surface air temperatures. This, in turn, gives rise to differences in low-level stability affecting the turbulence and the turbulent heat fluxes. The increase in modelled upward sensible heat flux during the morning transition is typically too weak and the growth of the convective boundary layer before noon is too slow. This is related to weak modelled near-surface winds during the morning hours. The agreement between the models, the LES and observations is the best during the late afternoon. From this intercomparison study, we find that modelling the diurnal cycle is still a big challenge. For the convective part of the diurnal cycle, some of the first-order schemes perform somewhat better while the turbulent kinetic energy (TKE) schemes tend to be slightly better during nighttime conditions. Finer vertical resolution tends to improve results to some extent, but is certainly not the solution to all the deficiencies identified.
Pharmaceutical residues and other emerging substances commonly summarised as micropollutants pass through wastewater treatment plants (WWTPs) and end up in the receiving waters and sludge. Many ...studies have investigated the removal efficiency of various techniques but a holistic evaluation of various relevant treatment alternatives regarding both the removal efficiency for various micropollutants, investment and operating costs, environmental impacts and future comprehensiveness is still lacking. This paper provides the results from a large 3-year project about the evaluation of sustainable treatment systems for removal of various micropollutants or disruptive effects at Swedish WWTPs and their environmental, economic and future sustainability. The presented results are based on our own pilot tests and related assessment and modelling efforts and provide a holistic view on advanced treatment of wastewater for removal of micropollutants.
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