The multi-wavelength electromagnetic afterglow from the binary neutron star merger GW170817/GRB 170817A has displayed long-term power-law brightening, and has presented challenges to post-merger ...models of the non-thermal emission. The most recent radio observations up to 200 days post-merger suggest that the afterglow has finally peaked and may now be fading, but fading has not been confirmed in the X-rays. We present new, deep Chandra observations of GW170817/GRB 170817A at 260 days post-merger that reveal an X-ray flux of erg s−1 cm−2, and confirm that the X-ray light curve is now also fading. Through rigorous comparisons with previous Chandra observations of GW170817/GRB 170817A, X-ray fading is detected between 160 and 260 days post-merger at a 4.4 significance on the basis of the X-ray data alone. We further constrain the X-ray photon index to steepen by <0.5 at 3.1 significance during this period, which disfavors the passing of the synchrotron cooling frequency through the X-ray band as the cause of the observed fading. These observations remain consistent with optically thin synchrotron afterglow emission. If this afterglow emission arises from a quasi-spherical mildly relativistic outflow, the X-ray fading suggests that the outflow is now decelerating. Alternatively, if this afterglow arises from a successful off-axis structured jet, the X-ray fading suggests that emission from the jet core has already entered the line of sight.
Abstract
Electromagnetic observations of gravitational-wave and high-energy neutrino events are crucial in understanding the physics of their astrophysical sources. X-ray counterparts are especially ...useful in studying the physics of the jet, the energy of the outflow, and the particle acceleration mechanisms in the system. Ultraviolet and optical observations can help us constrain the mass and velocity of the outflow and provide hints on the viewing angle. We present the Neil Gehrels Swift Observatory prompt searches for X-ray and UV/optical counterparts to the joint gravitational-wave and high-energy neutrino coincident events that happened during the third observing run of LIGO/Virgo. Swift observed the overlap between gravitational-wave and neutrino error regions for three of the considerable (
p
-value < 1%) joint gravitational-wave and high-energy neutrino coincident alerts, which were generated by the IceCube Neutrino Observatory in real time after triggering by the LIGO/Virgo gravitational-wave public alerts. The searches did not associate any X-ray or UV/optical counterparts with any of the joint gravitational-wave and high-energy neutrino coincident events; however, the follow-up of these alerts significantly improved the tiling techniques covering regions between the gravitational-wave sky maps and the neutrino’s error regions, making the real-time system ready for future potential discoveries. We discuss the details of each follow-up procedure, the results of each search, and the plans for future searches.
Abstract We report on the discovery of Swift J010902.6-723710, a rare eclipsing Be/X-ray Binary system by the Swift SMC Survey (S-CUBED). Swift J010902.6-723710 was discovered via weekly S-CUBED ...monitoring observations when it was observed to enter a state of X-ray outburst on 2023 October 10. X-ray emission was found to be modulated by a 182 s period. Optical spectroscopy is used to confirm the presence of a highly inclined circumstellar disk surrounding a B0-0.5Ve optical companion. Historical UV and IR photometry is then used to identify strong eclipse-like features reoccurring in both light curves with a 60.623 day period, which is adopted as the orbital period of the system. Eclipsing behavior is found to be the result of a large accretion disk surrounding the neutron star. Eclipses are produced when the disk passes in front of the OBe companion, blocking light from both the stellar surface and circumstellar disk. This is only the third Be/X-ray binary to have confirmed eclipses. We note that this rare behavior provides an important opportunity to constrain the physical parameters of a Be/X-ray binary with greater accuracy than is possible in noneclipsing systems.
We report on the X-ray properties of the new transient Swift J0840.7−3516, discovered with Swift/BAT in 2020February, using extensive data from Swift, MAXI, NICER, and NuSTAR. The source flux ...increased for∼103safter the discovery, decayed rapidly over∼5 orders of magnitude in five days, and then remained almost constant over nine months. Large-amplitude short-term variations on timescales of 1–104s were observed throughout the decay. In the initial flux rise, the source showed a hard power-law-shaped spectrum with a photon index of∼1.0extending up to∼30 keV, above which an exponential cutoff was present. The photon index increased in the following rapid decay and became∼2 at the end of the decay. A spectral absorption feature at 3–4 keV was detected in the decay. It is not straightforward to explain all the observed properties by any known class of X-ray sources. We discuss the possible nature of the source, including a Galactic low-mass X-ray binary with multiple extreme properties and a tidal disruption event by a supermassive black hole or a Galactic neutron star.
ABSTRACT
We present the Extragalactic Serendipitous Swift Survey (ExSeSS), providing a new well-defined sample constructed from the observations performed using the Swift X-ray Telescope. The ExSeSS ...sample consists of 79 342 sources detected in the medium (1–2 keV), hard (2–10 keV), or total (0.3–10 keV) energy bands, covering 2086.6 deg2 of sky across a flux range of f0.3–10 keV ∼ 10−15 − 10−10 erg s−1 cm−2. Using the new ExSeSS sample we present measurements of the differential number counts of X-ray sources as a function of 2–10 keV flux that trace the population of Active Galactic Nuclei (AGNs) in a previously unexplored regime. We find that taking the line-of-sight absorption column density into account has an effect on the differential number count measurements and is vital to obtain agreement with previous results. In the hard band, we obtain a good agreement between the ExSeSS measurements and previous, higher energy data from NuSTAR and Swift/BAT when taking into account the varying column density of the ExSeSS sample as well as the X-ray spectral parameters of each of the samples we are comparing to. We also find discrepancies between the ExSeSS measurements and AGN population synthesis models, indicating a change in the properties of the AGN population over this flux range that is not fully described by current models at these energies, hinting at a larger, moderately obscured population at low redshifts (z ≲ 0.2) that the models are not currently taking into account.
Alterations in exocrine pancreatic function after acute pancreatitis Bejjani, Joseph; Ramsey, Mitchell L.; Lee, Peter J. ...
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... et al.,
06/2024, Letnik:
24, Številka:
4
Journal Article
Recenzirano
Odprti dostop
Exocrine pancreatic dysfunction (EPD) is a malabsorptive complication of pancreatic disorders that can lead to a host of symptoms ranging from flatulence to diarrhea and contribute to weight loss and ...metabolic bone disease. It is increasingly recognized to occur after acute pancreatitis (AP), including episodes with mild severity. The risk of developing EPD after AP is influenced by a range of factors, including the degree of acinar cell destruction and inflammation during AP, and persistent structural derangements following AP. In this article, we discuss the epidemiology, pathophysiology, and clinical management of EPD after AP while highlighting key knowledge gaps.
ABSTRACT
High-energy neutrinos are a promising tool for identifying astrophysical sources of high and ultra-high energy cosmic rays (UHECRs). Prospects of detecting neutrinos at high energies (≳TeV) ...from blazars have been boosted after the recent association of IceCube-170922A and TXS 0506+056. We investigate the high-energy neutrino, IceCube-190331A, a high-energy starting event (HESE) with a high likelihood of being astrophysical in origin. We initiated a Swift/XRT and UVOT tiling mosaic of the neutrino localization and followed up with ATCA radio observations, compiling a multiwavelength spectral energy distribution (SED) for the most likely source of origin. NuSTAR observations of the neutrino location and a nearby X-ray source were also performed. We find two promising counterpart in the 90 per cent confidence localization region and identify the brightest as the most likely counterpart. However, no Fermi/LAT γ-ray source and no prompt Swift/BAT source is consistent with the neutrino event. At this point, it is unclear whether any of the counterparts produced IceCube-190331A. We note that the Helix Nebula is also consistent with the position of the neutrino event and we calculate that associated particle acceleration processes cannot produce the required energies to generate a high-energy HESE neutrino.
Diabetes mellitus following an episode of acute pancreatitis (AP) is an increasingly discussed complication, but there are sparse prospective data on the incidence and risk factors. We evaluated data ...from a prospective, multicenter observational cohort study that enrolled adults hospitalized with AP between 2017 and 2021 and followed them for one year. Ninety-eight participants who completed 12-month follow-up were included in this analysis. Diabetes status was assessed using a combination of measured glycated hemoglobin (HbA1c) at predetermined time intervals or physician diagnosis. In 68 participants without diabetes at enrollment, the cumulative incidence of new-onset diabetes was 4.4 % (n = 3) at 3 months and 10.3 % (n = 7) at 12 months. No differences were observed in demographic or pancreatitis-related characteristics between those who did versus did not develop diabetes, in part due to small sample size. In summary, new-onset diabetes was identified in approximately 10 % within one year after an episode of AP. Larger prospective studies are needed to further define the incidence, risk factors, and mechanisms of diabetes and pre-diabetes following AP. NCT03063398.
Pain is common in chronic pancreatitis (CP) and profoundly reduces quality of life (QoL). Multiple underlying mechanisms contribute to a heterogenous pain experience and reduce efficacy of pain ...management. This study was designed to characterize the distribution of mechanism-based pain phenotypes in painful CP. The data analyzed were collected as part of the PROspective Evaluation of Chronic Pancreatitis for EpidEmiologic and Translational StuDies, an NCI/NIDDK-funded longitudinal study of the natural history of CP. The PROspective Evaluation of Chronic pancreatitis for EpidEmiologic and translational stuDies includes patient-reported outcome (PRO) measures of pain, medication use, global health, and QoL. Of subjects (N = 681) with CP, 80% experienced abdominal pain within the year before enrollment. Subjects who experienced pain in the week before enrollment (N = 391) completed PROMIS Neuropathic and Nociceptive Pain Quality instruments which were then used to classify them by pain type: 40% had nociceptive, 5% had neuropathic-like, and 32% had both types of pain. The prevalence of having both types of pain was higher among women and subjects with diabetes mellitus, whereas nociceptive-only pain was more prevalent among men and those with pancreatic duct stricture. Other factors, including pain medication use and healthcare utilization, did not differ between groups based on pain type. Subjects in the Both group had significantly worse health and QoL scores relative to those with nociceptive-only pain, suggesting that using psychosocial pain surveys may be useful for understanding pain subtypes in patients with CP. Additional research is needed to identify biochemical and biophysical signatures that may associate with and predict responses to mechanism-specific interventions.
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