We report on the expected sensitivity of dedicated scintillator-based detectors at the LHC for elementary particles with charges much smaller than the electron charge. The dataset provided by a ...prototype scintillator-based detector is used to characterise the performance of the detector and provide an accurate background projection. Detector designs, including a novel slab detector configuration, are considered for the data taking period of the LHC to start in 2022 (Run 3) and for the high luminosity LHC. With the Run 3 dataset, the existence of new particles with masses between 10 MeV and 45 GeV could be excluded at 95% confidence level for charges between 0.003e and 0.3e, depending on their mass. With the high luminosity LHC dataset, the expected limits would reach between 10 MeV and 80 GeV for charges between 0.0018e and 0.3e, depending on their mass
Current developmental status of thermoelectric (QVD) detectors Gulian, A; Wood, K; Van Vechten, D ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
03/2004, Letnik:
520, Številka:
1-3
Journal Article
Recenzirano
Practical implementation of thermoelectric (QVD) detectors requires cryogenic thermoelectric sensors with a high figure of merit. For this requirement there can be different solutions: thin films, ...bulk materials and whiskers. Initial prototype QVD devices used Au–Fe thin film sensors. Another class of materials, lanthanum (cerium) hexaborides La(Ce)B6, has higher Seebeck coefficient at cryogenic temperatures, and therefore one can expect higher figures of merit for devices based on these materials. To utilize La(Ce)B6 crystals with different La–Ce content as sensor elements we investigated their kinetic properties. Then we explored prototype devices based on bulk single-crystalline sensors. Subsequently, we manufactured and successfully tested a candidate single-photon detector device with a sharp-end hexaboride sensor and small bismuth absorber.
Toward ultimate performance limits of thermoelectric (QVD) detectors Wood, K; Van Vechten, D; Fritz, G ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
03/2004, Letnik:
520, Številka:
1-3
Journal Article
Recenzirano
‘QVD’ detectors are based on thermoelectric heat-to-voltage (Q→V) conversion and digital (V→D) readout. In theory, they are competitive with superconducting tunnel junction detectors and transition ...edge sensor devices. We analyze the performance of the QVD detectors with different design architectures. It is concluded that the detectors with lanthanum–cerium hexaboride sensors can be very fast: up to 100MHz counting rates for UV photons. In addition to traditional astrophysical applications, these detectors can be applied to the tasks of quantum computing and communication.
Phys. Rev. D 102, 032002 (2020) We report on a search for elementary particles with charges much smaller than
the electron charge using a data sample of proton-proton collisions provided by
the CERN ...Large Hadron Collider in 2018, corresponding to an integrated
luminosity of 37.5 fb$^{-1}$ at a center-of-mass energy of 13 TeV. A prototype
scintillator-based detector is deployed to conduct the first search at a hadron
collider sensitive to particles with charges ${\leq}0.1e$. The existence of new
particles with masses between 20 and 4700 MeV is excluded at 95% confidence
level for charges between $0.006e$ and $0.3e$, depending on their mass. New
sensitivity is achieved for masses larger than $700$ MeV.
We report on a search for elementary particles with charges much smaller than the electron charge using a data sample of proton-proton collisions provided by the CERN Large Hadron Collider in 2018, ...corresponding to an integrated luminosity of 37.5 fb\(^{-1}\) at a center-of-mass energy of 13 TeV. A prototype scintillator-based detector is deployed to conduct the first search at a hadron collider sensitive to particles with charges \({\leq}0.1e\). The existence of new particles with masses between 20 and 4700 MeV is excluded at 95% confidence level for charges between \(0.006e\) and \(0.3e\), depending on their mass. New sensitivity is achieved for masses larger than \(700\) MeV.
Assessment of Management of a Golf Course by Means of Sustainability Indicators Pacini, Gaio Cesare; Nicolina Staglianòauthor Department of Agri-Food Production and Environmental Sciences, University of Florence, Florence, Italy; Francesco MeoauthorCircolo Golf Ugolino, Impruneta (FI), Italy ...
2015
Journal Article
The incidence of insulin resistance and metabolic syndrome correlates with the availability of magnesium (Mg). We studied the effect of oral Mg supplementation on insulin sensitivity and other ...characteristics of the metabolic syndrome in normomagnesemic, overweight, insulin resistant, non-diabetic subjects. Subjects were tested for eligibility using oral glucose tolerance test (OGTT) and subsequently randomized to receive either Mg-aspartate-hydrochloride (n = 27) or placebo (n = 25) for 6 months. As trial endpoints, several indices of insulin sensitivity, plasma glucose, serum insulin, blood pressure and lipid profile were determined. Mg supplementation resulted in a significant improvement of fasting plasma glucose and some insulin sensitivity indices (ISIs) compared to placebo. Blood pressure and lipid profile did not show significant changes. The results provide significant evidence that oral Mg supplementation improves insulin sensitivity even in normomagnesemic, overweight, non-diabetic subjects emphasizing the need for an early optimization of Mg status to prevent insulin resistance and subsequently type 2 diabetes.
The ability to modify the thiocarbonylthio end-groups of RAFT polymers is important for applications where an inert or highly functionalised material is required. Here we report a copper promoted ...cross-coupling reaction between RAFT polymer end-groups and aryl boronic acids. This method gives high conversion to the modified polymers, and is compatible with a wide variety of functional molecules.
Background: To compare the efficacy and safety of three different chemotherapy doublets in the treatment of advanced pancreatic cancer (PC). Patients and methods: At total of 190 patients were ...randomly assigned to receive capecitabine 1000 mg/m2 twice daily on days 1–14 plus oxaliplatin 130 mg/m2 on day 1 (CapOx), capecitabine 825 mg/m2 twice daily on days 1–14 plus gemcitabine 1000 mg/m2 on days 1 and 8 (CapGem) or gemcitabine 1000 mg/m2 on days 1 and 8 plus oxaliplatin 130 mg/m2 on day 8 (mGemOx). Treatment cycles were repeated every three weeks. The primary end point was progression-free survival (PFS) rate at 3 months; secondary end points included objective response rate, carbohydrate antigen 19-9 response, clinical benefit response, overall survival and toxicity. Results: The PFS rate after 3 months was 51% in the CapOx arm, 64% in the CapGem arm and 60% in the mGemOx arm. Median PFS was estimated with 4.2 months, 5.7 months and 3.9 months, respectively (P = 0.67). Corresponding median survival times were: 8.1 months (CapOx), 9.0 months (CapGem) and 6.9 months (mGemOx) (P = 0.56). Grade 3/4 hematological toxicities were more frequent in the two Gem-containing arms; grade 3/4 non-hematological toxicity rates did not exceed 15% in any arm. Conclusion: CapOx, CapGem and mGemOx have similar clinical efficacy in advanced PC. Each regimen has a distinct but manageable tolerability profile.
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