To determine the outcome and effect of surgical technique on limb function after surgery for rupture of the cranial cruciate ligament (RCCL) and injury to the medial meniscus in Labrador Retrievers.
...Prospective clinical study.
131 Labrador Retrievers with unilateral RCCL and injury to the medial meniscus and 17 clinically normal Labrador Retrievers.
Affected dogs had partial or complete medial meniscectomy and lateral suture stabilization (LSS), intracapsular stabilization (ICS), or tibial plateau leveling osteotomy (TPLO). Limb function was measured before surgery and 2 and 6 months after surgery. Treated dogs were evaluated to determine the probability that they could be differentiated from clinically normal dogs and tested to determine the likelihood that they achieved improvement.
No difference was found between LSS or TPLO groups, but dogs treated with ICS had significantly lower ground reaction forces at 2 and 6 months. Compared with clinically normal dogs only, 14.9% of LSS-, 15% of ICS-, and 10.9% of TPLO-treated dogs had normal limb function. Improvement was seen in only 15% of dogs treated via ICS, 34% treated via TPLO, and 40% treated via LSS.
Surgical technique can influence limb function after surgery. Labrador Retrievers treated via LSS, ICS, or TPLO for repair for of RCCL and medial meniscal injury managed with partial or complete meniscectomy infrequently achieve normal function. Results of LSS and TPLO are similar and superior to ICS.
To document peak vertical force (PVF) and vertical impulse (VI) in the pads of Greyhounds and Labrador Retrievers.
8 Greyhounds and 8 Labrador Retrievers.
Velocity and acceleration were restricted to ...ranges of 0.9 to 1.1 m/s and -0.1 to 0.1 m/s2, respectively. The PVF and VI measurements were collected from digital pad (DP)-2, -3, -4, and -5 and the metacarpal pad (McP) or metatarsal pad (MtP) of each limb in each dog.
We found no significant differences between the left and right forelimbs or hind limbs for any pad in either breed. Vertical forces in the forelimb were always greater than those in the hind limb. The PVF in the forelimbs of Greyhounds was greatest in DP-3, -4, and -5 and DP-3, DP-4, and the MtP in the hind limbs. The VI in Greyhound forelimbs was greatest in DP-3, -4, and -5 but greatest in DP-4 in the hind limbs. The PVF in the forelimbs of Labrador Retrievers was greatest in the McP, whereas in the hind limbs it was greatest in DP-4. The VI in Labrador Retriever forelimbs was greatest in DP-3, DP-4, and the McP but greatest in DP-3 and -4 in the hind limbs. Significant differences were detected in load distribution between the breeds.
This study confirms that DP-3 and DP-4 are major weight-bearing pads in dogs. However, loads were fairly evenly distributed, and DP-5 and the McP or MtP bear a substantial amount of load in both breeds.
Objectives— To evaluate the mechanism of vascular occlusion after placement of an ameroid constrictor (AC) on a large intra‐abdominal vein and document changes in blood flow.
Study Design— ...Experimental study.
Animals— Six adult dogs.
Methods— Six 6.5 mm ACs were digitally scanned to measure area and circumference of the ameroid and inner lumen before surgery. ACs were surgically positioned around the left common iliac vein (CIV) in each dog. Peri‐vascular ultrasonic flow probes were positioned on the left CIV cranial to the AC, and on the right CIV as an internal control. Blood flow measurements were recorded daily until there was no, or prolonged minimal, blood flow, at which time the dogs were euthanatized. Left and right CIVs were removed for histologic evaluation, and the ACs re‐scanned to evaluate degree and direction of expansion of the ameroid.
Results— Reduction in blood flow occurred within 10 days in all dogs. Three dogs had complete occlusion by day 10 from thrombus formation. One dog damaged the flow probes at 13 days when blood flow was approximately 50% of intra‐operative values; the dog was euthanatized at 37 days; there was partial occlusion from thrombosis. Two dogs had persistent low blood flow and occlusion from thrombus formation when euthanatized at 59 and 98 days. There was a significant increase in total AC area and outer circumference, and decrease in luminal area and inner circumference when presurgical and postocclusion measurements were compared.
Conclusions— Vascular occlusion after placement of an AC on a large intra‐abdominal vein occurred from thrombus formation.
Clinical Relevance— A similar pattern of venous occlusion may occur after placement of an AC on a portosystemic shunt, which may lead to both short‐ and long‐term complications associated with portal hypertension.
The objectives of this study were to determine local recurrence rate, clinical outcome, and prognostic value of the number of argyrophylic nucleolar organizer regions (AgNORs), presence of ...proliferating cell nuclear antigen (PCNA), and number of Ki‐67‐positive nuclei after incomplete surgical excision of canine cutaneous grade II mast cell tumors (MCTs). This retrospective study included 30 MCTs in 28 dogs. Medical records were examined and follow‐up information was obtained from owners and referring veterinarians. Only cases in which excision was incomplete and no anvcillary therapy (other than prednisone) for MCT was given were included. Paraffin‐embedded tumor tissues were retrieved for AgNORs, PCNA, and Ki‐67 staining. Median follow‐up time was 811.5 days. Seven (23.3%) tumors recurred locally. Median time to local recurrence was not reached with a mean of 1,713 days. The estimated proportions of tumors that recurred locally at 1,2, and 5 years were 17.3, 22.1, and 33.3%, respectively. Eleven (39.3%) dogs developed MCTs at other cutaneous locations. Median progression‐free survival was 1,044 days. Median overall survival was 1,426 days. The combination of Ki‐67 and PCNA scores was prognostic for local recurrence (P= .03) and development of local recurrence was prognostic for decreased overall survival (P= .04). Results suggest that a minority of incompletely excised MCTs recur. Therefore, ancillary local therapies may not always be necessary. However, local recurrence can negatively affect survival of the affected dogs. Cellular proliferation indices may indicate the likelihood of MCT recurrence after incomplete excision.
A 7-year-old castrated male Miniature Schnauzer was examined because of labored breathing and episodes of respiratory distress that progressed to collapse. On cervical radiographs, a focal soft ...tissue mass in the caudal cervical portion of the trachea was observed, and during tracheoscopy, a 1 x 1 cm, pedunculated, multinodular, pink, intraluminal mass extending from the dorsal tracheal membrane and obstructing approximately 80% of the tracheal lumen was seen. Tracheal resection and anastomosis was performed to remove the mass, and the dog recovered without complications. On histologic examination, the mass consisted of a large accumulation of homogeneous, faintly fibrillar eosinophilic material admixed with a predominantly plasma cell infiltrate; examination of sections stained with thioflavin T and Congo red stain confirmed that the eosinophilic material was amyloid. A diagnosis of nodular, immunocyte-derived (AL) amyloidosis was made. Seventeen months after surgery, the dog had a relapse of respiratory distress because of an extramedullary plasmacytoma involving the trachea.
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