O carcinoma triquilemal é um tumor raro, que ocorre, geralmente, na pele exposta ao sol, principalmente face, couro cabeludo, pescoço e dorso das mãos, em indivíduos idosos, entre a 4ª e 9ª décadas ...de vida, sem predilação por sexo. O presente estudo mostra um caso de carcinoma triquilemal, recidivado, de difícil tratamento, em mesma topografia de um carcinoma basocelular tratado previamente com cirurgia e radioterapia.The trichilemmal carcinoma is a rare tumor that usually occurs on sun-exposed skin, especially on the face, scalp, neck and back of hands, mainly in elderly subjects but commonly between the 4th and 9th decades of life. It is not a gender-based illness. This study shows a difficult to treat case of recurrent trichilemmal carcinoma on the same location of a basal-cell carcinoma previously treated with surgery and radiotherapy.
Carcinoma triquilemal: relato de caso Roismann, Miguel; Freitas, Rosyane Rena de; Ribeiro, Leandro Carvalho ...
Anais brasileiros de dermatología,
10/2011, Letnik:
86, Številka:
5
Journal Article
Recenzirano
Odprti dostop
O carcinoma triquilemal é um tumor raro, que ocorre, geralmente, na pele exposta ao sol, principalmente face, couro cabeludo, pescoço e dorso das mãos, em indivíduos idosos, entre a 4ª e 9ª décadas ...de vida, sem predilação por sexo. O presente estudo mostra um caso de carcinoma triquilemal, recidivado, de difícil tratamento, em mesma topografia de um carcinoma basocelular tratado previamente com cirurgia e radioterapia.
The trichilemmal carcinoma is a rare tumor that usually occurs on sun-exposed skin, especially on the face, scalp, neck and back of hands, mainly in elderly subjects but commonly between the 4th and 9th decades of life. It is not a gender-based illness. This study shows a difficult to treat case of recurrent trichilemmal carcinoma on the same location of a basal-cell carcinoma previously treated with surgery and radiotherapy.
A polinização constitui um processo fundamental para a perpetuação de várias espécies vegetais, e o desenvolvimento dos frutos e das sementes está diretamente relacionado com a polinização das ...flores. Dessa forma, o objetivo deste trabalho foi verificar a influência de agentes polinizadores na produção e qualidade de sementes de cenoura e de pimenta doce em sistema de cultivo protegido. No ensaio de cenoura utilizaram-se, em telados, os tratamentos de polinização com as abelhas Arapuá (Trigona spinipes), Jataí (Tetragonisca angustula), Tibuna (Nannotrigona (Scaptotrigona) bipunctata), moscas (Musca domestica), polinização manual e livre (fora do telado). No ensaio de pimenta doce, utilizaram-se os tratamentos de polinização com as abelhas Arapuá (Trigona spinipes), Jataí (Tetragonisca angustula), Marmelada (Frieseomellita varia), polinização manual e livre (auto fecundação). A utilização de abelhas Jataí e Tibuna apresentou grande potencial para a produção de sementes de cenoura em condições de cultivo protegido. Para a produção de sementes de pimenta doce não há necessidade de utilização de agentes polinizadores, no entanto a presença desses agentes aumenta o peso dos frutos. A qualidade fisiológica das sementes das duas espécies não foi influenciada pelos diferentes tipos de polinização.
Pollination is a fundamental process for the perpetuation of various plant species, and the development of fruits and seeds is directly related to the pollination of flowers. Thus, the aim of this study was to assess the influence of pollinators on seed production and quality of carrot and sweet pepper under greenhouse conditions. In the carrot study, plants were grown in cages, and the following treatments were used: pollination with Arapuá (Trigona spinipes) bees, Jataí (Tetragonisca angustula) bees, Tibuna (Nannotrigona (Scaptotrigona) bipunctata) bees, flies (Musca domestica), hand pollination, and free pollination (outside the greenhouse). In the sweet pepper study, the following treatments were used: pollination with Arapuá (Trigona spinipes) bees, Jataí (Tetragonisca angustula) bees, Marmelada (Frieseomellita varia) bees, hand pollination and free (self fertilization). The use of Jataí and Tibuna bees showed a great potential for carrot seed production in greenhouse conditions. For the production of sweet pepper seeds the use of pollinators is not necessary, but the presence of these agents increases the fruit weight. The physiological seed quality of both species was not influenced by different types of pollination.
Foi analisada a qualidade do Sistema de Informações sobre Mortalidade (SIM) para óbitos por causas externas no Estado do Paraná, Brasil, entre 1979 e 2005, focalizando os eventos de intenção ...indeterminada. Os óbitos foram agrupados em acidentes de transporte, homicídios, suicídios, eventos de intenção indeterminada, e calculadas a mortalidade proporcional e a variação percentual anual dos coeficientes entre triênios. Os acidentes de transporte foram as causas mais freqüentes de óbito no período e, a partir de 1997, os homicídios passam à segunda posição. Os óbitos por eventos de intenção indeterminada por arma (de fogo ou branca) reduziram de 4,8% em 1981 para 0,3% em 2005. Os coeficientes dos eventos (todos) de intenção indeterminada passaram de 14,9 óbitos por 100 mil habitantes em 1979/1981 para 2,0 em 2003/2005. A variação percentual anual foi de -13,1% entre 1980 e 1985; -6% entre 1996 e 2000 e -11% entre 2000 e 2004. Os resultados evidenciam a boa qualidade do SIM sobre causas externas no Estado do Paraná, permitindo análises com potencial para subsidiar ações de prevenção e promoção da saúde.This study analyzed the quality of data from the Mortality Information System (SIM) for deaths due to external causes in the State of Paraná, Brazil, 1979 to 2005, focusing on events of undetermined intent. Deaths were grouped in motor vehicle accidents, homicides, suicides, and events of undetermined intent, and proportional mortality and relative annual variation of rates over the three-year period were analyzed. Motor vehicle accidents (more than 30% of the total) were the most frequent causes of death throughout the period, and since 1997 homicides have become the second most frequent cause. Deaths due to events of undetermined intent caused by weapons (firearms or knives) decreased from 4.8% in 1981 to 0.3% in 2005. Mortality rates for events of undetermined intent (overall) decreased from 14.9 deaths per 100,000 inhabitants in 1979-81 to 2.0 in 2003-05. Annual percentage variation was -13.1% from 1980 to 1985, -6% from 1996 to 2000, and -11% from 2000 to 2004. The findings show the good quality of SIM data on external causes in the State of Paraná, allowing analyses with the potential to support programs to prevent injuries as well as health promotion measures.
Foi analisada a qualidade do Sistema de Informações sobre Mortalidade (SIM) para óbitos por causas externas no Estado do Paraná, Brasil, entre 1979 e 2005, focalizando os eventos de intenção ...indeterminada. Os óbitos foram agrupados em acidentes de transporte, homicídios, suicídios, eventos de intenção indeterminada, e calculadas a mortalidade proporcional e a variação percentual anual dos coeficientes entre triênios. Os acidentes de transporte foram as causas mais freqüentes de óbito no período e, a partir de 1997, os homicídios passam à segunda posição. Os óbitos por eventos de intenção indeterminada por arma (de fogo ou branca) reduziram de 4,8% em 1981 para 0,3% em 2005. Os coeficientes dos eventos (todos) de intenção indeterminada passaram de 14,9 óbitos por 100 mil habitantes em 1979/1981 para 2,0 em 2003/2005. A variação percentual anual foi de -13,1% entre 1980 e 1985; -6% entre 1996 e 2000 e -11% entre 2000 e 2004. Os resultados evidenciam a boa qualidade do SIM sobre causas externas no Estado do Paraná, permitindo análises com potencial para subsidiar ações de prevenção e promoção da saúde.
This study analyzed the quality of data from the Mortality Information System (SIM) for deaths due to external causes in the State of Paraná, Brazil, 1979 to 2005, focusing on events of undetermined intent. Deaths were grouped in motor vehicle accidents, homicides, suicides, and events of undetermined intent, and proportional mortality and relative annual variation of rates over the three-year period were analyzed. Motor vehicle accidents (more than 30% of the total) were the most frequent causes of death throughout the period, and since 1997 homicides have become the second most frequent cause. Deaths due to events of undetermined intent caused by weapons (firearms or knives) decreased from 4.8% in 1981 to 0.3% in 2005. Mortality rates for events of undetermined intent (overall) decreased from 14.9 deaths per 100,000 inhabitants in 1979-81 to 2.0 in 2003-05. Annual percentage variation was -13.1% from 1980 to 1985, -6% from 1996 to 2000, and -11% from 2000 to 2004. The findings show the good quality of SIM data on external causes in the State of Paraná, allowing analyses with the potential to support programs to prevent injuries as well as health promotion measures.
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Sucrose feeding (SF) induces oxidative stress, metabolic abnormalities and high blood pressure (HBP). The aim of this study was to investigate if dietary supplementation with vitamin C ...ameliorates HBP, hyperinsulinaemia and the mRNA renal expression levels of AT1, NAD(P)H oxidase subunits (p47phox and gp91phox), CuZnSOD induced by SF. Wistar rats (150–180g) were treated, for 30 days, with 20% sucrose solution (SC, n=15) instead of drinking water (CC, n=24). Ascorbic acid (AA, 150 mg/kg) was given by gavage to sucrose‐fed (SAA; n=17) or control rats (CAA; n=25) for the last 7 days of SF. Mean arterial pressure (MAP) was recorded on a Power Lab System. The mRNA expression levels were analyzed in the cortical renal tissue by Real Time RT‐ PCR. An increase (P<0.05) in MAP was observed in SC compared to CC (136±3; 111±4 mmHg). AA supplementation decreases (P<0.05) MAP either in CAA or SAA (102±3; 105±1 mmHg) rats. Basal glucose levels were unchanged but plasma insulin increased (P<0.05) after SF; no alterations were observed after AA. SF increased (P<0.05) p47phox and gp91phox expression but did not change CuZnSOD or AT1 mRNA expression. However, AA reversed the increase of mRNA expression of NAD(P)H oxidase subunits and it reduced (P<0.05) AT1 expression. CuZnSOD expression was unchanged after AA administration. These findings suggest AA ameliorates HBP probably by decreasing oxidative stress induced by SF. Supported by FAPESP (06/58219‐4).
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Dysregulation of sodium and/or water reabsorption by the kidney may contribute to hypertension. As chronic sucrose feeding reduces food intake and in consequence of this, the sodium ...(Na) intake. The objective of the present study was to investigate the role of kidney sodium and water channels on blood pressure increase in sucrose‐fed rats (SC). Wistar rats (150–180g) received, for 30 days, food
ad libitum
and sucrose solution (20%) (SC =7) or tap water (control group, C =8). The food ingestion was quantified using a metabolic cage and 1 mg of Na was given by gavage for another group of 5 sucrose fed‐rats (SS), also for 30 days (once a day) in order to normalize the sodium ingestion between SS and C. Mean arterial pressure (MAP) was recorded by a Power Lab system. The mRNA expression levels of epithelial sodium channel (ENaC) and water channel protein (AQP2) were analyzed in the cortical kidney tissue by Real Time RT‐PCR technique. MAP increases (P<0.05) in SC (128±1 mmHg) compared to C (102±4 mmHg) rats; MAP was 132±3 mmHg, in SS rats. Compared to C rats the ENaC and AQP2 expression levels were increased (P<0.05) in SC rats (ENaC: SC=1.95±0,19; C=1.03±0,07; AQP2: SC=2.12±0,19, C=1.07±0,10 arbitrary units). However, in SS group the high expression levels of ENaC and AQP2 were reversed (ENaC: 0,74±0,6, AQP2: 0,99±0,12 arbitrary units) but not MAP. Taken altogether, the results presented here indicate that in chronic sucrose fed‐rats the increased MAP is Na‐independent.
Supported by FAPESP, CNPq
Estudo de base populacional para determinar perfis de óbitos neonatais precoces ocorridos em Belo Horizonte, Minas Gerais, Brasil, de 2000 a 2003. A defini ão dos perfis de causas amplia ...possibilidade de análise sob enfoque de evitabilidade, justificada pela persistência de altas taxas de mortalidade neonatal precoce. Três perfis foram gerados, a partir do enfoque de causas múltiplas, sob a perspectiva dos conjuntos nebulosos ("fuzzy sets"), utilizando-se técnica Grade of Membership. Relacionaram-se esses perfis ao peso de nascimento e a natureza jurídica do hospital de ocorrência do óbito. Nos hospitais da rede privada ocorreram "óbitos dificilmente preveníveis, com menção de malformação congênita" (perfil 2). Aos hospitais do Sistema Único de Saúde (SUS) associaram-se dois perfis distintos. Nos hospitais contratados/conveniados ocorreram os "óbitos passíveis de prevenção" (perfil 1) e na rede própria os "óbitos de prematuros" (perfil 3). A tipologia observada aponta para necessidade de adoção de políticas diferenciadas na rede SUS: prioritariamente, na rede contratada/conveniada, ações voltadas para credenciamento e avaliação da qualidade da assistência; e, em toda rede, adoção rotineira de protocolos assistenciais e medidas profiláticas, redutores da morbimortalidade neonatal.This population-based study aimed to determine the profile of early neonatal deaths in Belo Horizonte, Minas Gerais, Brazil, from 2000 to 2003. Profiles were analyzed from the perspective of avoidability, justified by persistently high early neonatal mortality rates in the city. Three profiles were generated for multiple causes of death from the perspective of fuzzy sets, using the Grade of Membership method. Birth weight and the hospital's corporate status were also related to the three profiles. Private hospitals were characterized by so-called "difficult-to-prevent deaths, with mention of congenital malformations" (profile 2). The Unified National Health System (SUS) generated two distinct profiles. Private maternity facilities contracted out by the SUS showed "preventable deaths" (profile 1), while "premature deaths" (profile 3) occurred in the public Federal and State maternity hospitals. This typology highlights the need to adopt differential policies in the SUS, focusing on evaluation and accreditation for maternity facilities contracted out by the SUS and - for the system as a whole - on the routine adoption of protocols for childbirth care and prophylactic measures that are known to reduce neonatal morbidity and mortality.
Estudo de base populacional para determinar perfis de óbitos neonatais precoces ocorridos em Belo Horizonte, Minas Gerais, Brasil, de 2000 a 2003. A definição dos perfis de causas amplia ...possibilidade de análise sob enfoque de evitabilidade, justificada pela persistência de altas taxas de mortalidade neonatal precoce. Três perfis foram gerados, a partir do enfoque de causas múltiplas, sob a perspectiva dos conjuntos nebulosos ("fuzzy sets"), utilizando-se técnica Grade of Membership. Relacionaram-se esses perfis ao peso de nascimento e a natureza jurídica do hospital de ocorrência do óbito. Nos hospitais da rede privada ocorreram "óbitos dificilmente preveníveis, com menção de malformação congênita" (perfil 2). Aos hospitais do Sistema Único de Saúde (SUS) associaram-se dois perfis distintos. Nos hospitais contratados/conveniados ocorreram os "óbitos passíveis de prevenção" (perfil 1) e na rede própria os "óbitos de prematuros" (perfil 3). A tipologia observada aponta para necessidade de adoção de políticas diferenciadas na rede SUS: prioritariamente, na rede contratada/conveniada, ações voltadas para credenciamento e avaliação da qualidade da assistência; e, em toda rede, adoção rotineira de protocolos assistenciais e medidas profiláticas, redutores da morbimortalidade neonatal.
This population-based study aimed to determine the profile of early neonatal deaths in Belo Horizonte, Minas Gerais, Brazil, from 2000 to 2003. Profiles were analyzed from the perspective of avoidability, justified by persistently high early neonatal mortality rates in the city. Three profiles were generated for multiple causes of death from the perspective of fuzzy sets, using the Grade of Membership method. Birth weight and the hospital's corporate status were also related to the three profiles. Private hospitals were characterized by so-called "difficult-to-prevent deaths, with mention of congenital malformations" (profile 2). The Unified National Health System (SUS) generated two distinct profiles. Private maternity facilities contracted out by the SUS showed "preventable deaths" (profile 1), while "premature deaths" (profile 3) occurred in the public Federal and State maternity hospitals. This typology highlights the need to adopt differential policies in the SUS, focusing on evaluation and accreditation for maternity facilities contracted out by the SUS and - for the system as a whole - on the routine adoption of protocols for childbirth care and prophylactic measures that are known to reduce neonatal morbidity and mortality.
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