Highlights • Concentration of monobulks from 2008/2009 seasonal vaccine. • Formulation and coating of concentrated antigen on to microstructure patches. • Stability of the coated antigen upon storage ...at 4 °C and RT. • Evaluation of vaccine coated microstructures patches in a guinea pig model.
In view of Run3 (2020) the LHCb experiment is planning a major upgrade to fully readout events at 40 MHz collision rate. This in order to highly increase the statistic of the collected samples and go ...further in precision beyond Run2. An unprecedented amount of data will be produced, which will be fully reconstructed real-time to perform fast selection and categorization of interesting events. The collaboration has decided to go for a fully software trigger which will have a total time budget of 13 ms to take a decision. This calls for faster hardware and software. In this talk we will present our efforts on the application of new technologies, such as GPU cards, for the future LHCb trigger system. During Run2 a node equipped with a GPU has been inserted in the LHCb online monitoring system; during normal data taking, a subset of real events is sent to the node and processed in parallel by GPU-based and CPU-based track reconstruction algorithms. This gives us the unique opportunity to test the new hardware and the new algorithms in a realistic environment. We will present the setup of the testbed, the algorithms developed for parallel architectures and discuss the performance compared to the current LHCb track reconstruction algorithms.
The NA62 experiment collected a large sample of charged kaon decays in 2007 with a highly efficient trigger for decays into electrons. A measurement of the π0 electromagnetic transition form factor ...slope parameter from 1.11×106 fully reconstructed K±→π±πD0, πD0→e+e−γ events is reported. The measured value a=(3.68±0.57)×10−2 is in good agreement with theoretical expectations and previous measurements, and represents the most precise experimental determination of the slope in the time-like momentum transfer region.
The branching ratio (BR) for the decay K+ → π+ν is a sensitive probe for new physics. The NA62 experiment at the CERN SPS will measure this BR to within about 10 . To reject the background from ...dominant kaon decays with final state photons, the large-angle photon vetoes (LAVs) must detect photons of energy as low as 200 MeV with an inefficiency of less than 10−4. The LAV detectors make use of lead glass blocks recycled from the OPAL electromagnetic calorimeter barrel. We describe the mechanical design and challenges faced during construction, the characterization of the lead glass blocks and solutions adopted for monitoring their performance, and the development of front-end electronics to allow simultaneous time and energy measurements over an extended dynamic range using the time-over-threshold technique. Our results are based on test-beam data and are reproduced by a detailed Monte Carlo simulation that includes the readout chain.
A precision measurement of the ratio RK of the rates of kaon leptonic decays K±→e±ν and K±→μ±ν with the full data sample collected by the NA62 experiment at CERN in 2007–2008 is reported. The result, ...obtained by analysing ∼150000 reconstructed K±→e±ν candidates with 11% background contamination, is RK=(2.488±0.010)×10−5, in agreement with the Standard Model expectation.
The NA62 experiment at CERN SPS aims at measuring-100 events of the very rare decay K+ →π +ννˉ (BR∼8.5xlO∼10). It poses stringent requirements on PID capabilities to reject the overwhelming π+π0 ...(63%) and Kμ2(21%) backgrounds. The photon veto system must provide a rejection factor of 10∼8 on π0 decays. As a main γ veto detector, the NA48 liquid Kripton calorimeter will be used. To have full geometrical acceptance up to 50 mr, a set of 12 veto stations should be placed along the vacuum decay tank, with an inefficiency <10∼4 in a wide energy range (200 MeV-35 GeV). Good energy resolution (∼10% at 1 GeV) for threshold definition, good time resolution (∼1 ns) to be used at the trigger level, sensitivity to MIP for calibration with muons of the beam halo are needed. A moderate segmentation in the azimuthal angle is desirable, for reducing the counting rate and providing information on the γ direction. We performed an intense R&D program on three solutions: “spaghetti” calorimeter, lead/scintillator sandwich calorimeter, and original re-use of the existing barrel of the OPAL lead-glass e.m. calorimeter. Studies have been performed at the Frascati BTF beam and all three meet the efficiency requirements. The final choice uses a peculiar radial arrangement of lead-glasses in rings. Front-end electronics has been designed to cover the tree orders of magnitude of the signal, contributing to the trigger, and integrated in the general TDAQ, while keeping low cost and simplicity. The first five full veto stations have been constructed. Two tests have been done and problems found fixed. We will discuss about R&D for the technology choice, LAV construction, test beams results and simulation performance.
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