Swing effect of spatial soliton Garzia, F; Sibilia, C; Bertolotti, M
Optics communications,
07/1997, Letnik:
139, Številka:
4
Journal Article
Recenzirano
A novel transverse oscillatory behavior of a spatial soliton is presented. The controlling parameter of the spatial oscillation period is constituted by the intensity of the input beam. The scheme is ...based on an interesting property of a soliton in a waveguide with transverse Gaussian refractive index profile.
Abstract Elevated levels of TNF-α have been associated with progressive disease in patients with chronic lymphocytic leukemia (CLL). Thalidomide has been shown to inhibit production of TNF-α. We ...investigated the effects of thalidomide on clinical outcome and TNF-α serum levels in five pre-treated CLL patients. The schedule consisted on daily thalidomide (Thal), oral fludarabine (Flu) and oral cyclophosphamide (CTX). Median duration of treatment was 60 days; four patients stopped treatment for disease progression and one patient for neurological toxicity. Serum TNF-α levels did not show any decrease during treatment. Low-dose thalidomide is not effective in CLL patients with refractory disease.
Introduction: In December 2019, an outbreak of pneumonia caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) quickly spread and the corona virus disease 2019 ...(COVID-19) became a pandemic. We report on a 54-year-old patient with SARS-CoV-2 infection suffering from septic shock due to nosocomial infection and pulmonary derangement caused by SARS-CoV-2. The patient was treated with polymyxin B hemoperfusion (PMX-HP), a blood purification therapy against septic shock, followed by continuous low flow extracorporeal CO2 removal therapy.
Case Report: A 54-year-old man was hospitalized for coronavirus disease 2019 (COVID-19). Chest computed tomography (CCT) showed extensive non-segmental ground glass opacity. Despite the initiation of standard therapy, respiratory failure progressed. After two days of polymyxin B hemoperfusion therapy (PMX-HP) with adjunctive corticosteroid for multi-resistant Gram-negative infection (Acinetobacter) the patient’s condition improved. In rapidly progressive COVID-19 cases with secondary infection, the early use of PMX-HP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung.
Conclusion: The concern of life-threatening bacterial infections in critically ill COVID-19 patients due to antibiotics resistance is high. Secondary bacterial infections may develop during or following COVID-19 infection. The use of PMX-HP in septic shock patients has resulted in decreased dependency on ventilators, which is a serious issue during this COVID-19 pandemic. Combined and less invasive approaches might be considered in COVID-19 patients with multiple organ failure (MOF).
We report on a 26-year-old female affected by Noonan syndrome (NS), a congenital disorder characterized by various phenotypic features and congenital anomalies) associated with a variety of ...autoimmune diseases, including systemic lupus erythematosus, celiac disease, and Hashimoto thyroiditis. Autoimmunity is seldom described in NS and the association between this congenital disease and three autoimmune disorders has not been previously reported. Should the occurrence of autoimmune disorders in NS be confirmed, a relevant clinical and laboratory evaluation of NS patients should be performed in order to clarify whether the immune system involvement represents only an occasional event or is a feature of the disease.
The LIFEBRIDGE B2T is a new portable cardiopulmonary bypass (CPB) system designed for temporary circulatory support. The LIFEBRIDGE B2T consists of a disposable patient unit with a CPB circuit, a ...control, and a base unit. The system weighs 20 kg. We used the LIFEBRIDGE B2T in four patients for circulatory support in beating heart coronary artery bypass graft for complete revascularization. The LIFEBRIDGE B2T was connected via femoral cannulation. Concentrations of free hemoglobin (fHb), interleukin (IL)-6, and -8 were measured. For venous blood drainage, 22-24 Fr cannulae and for arterial cannulation, 16-20 Fr cannulae were used. Average extracorporeal circulation (ECC) time was 61 +/- 18 minutes. During circulatory support, the system delivered an arterial blood flow between 3.1 and 4.1 L/min. The negative pressure at the venous drainage was between -79 and -45 mm Hg. During circulatory support, fHb concentration increased from 5.8 +/- 1.7 mg/dL to a maximum of 10.2 +/- 6.2 mg/dL. Also, IL-6 and -8 increased from 2.1 +/- 0.06 to 503.3 +/- 400.7 U/L and 5.9 +/- 0.9 to 66.5 +/- 46.8 U/L, respectively. The LIFEBRIDGE B2T is a new portable and safe circulatory support system. Connected via femoral cannulation, the system provides adequate arterial blood flow and an acceptable negative pressure at the venous cannula. The fHb concentration showed only a moderate increase during ECC.
Objective: To evaluate the association of IgG and IgM antibodies directed against different negatively charged phospholipids (that is, anticardiolipin (aCL), antiphosphatidylinositol, ...antiphosphatidylserine, and antiphosphatidic acid) and anti-β2-glycoprotein I (aβ2GPI), with Raynaud’s phenomenon in patients with systemic lupus erythematosus (SLE). Methods: Ninety three patients with SLE (81 female), 40 with and 53 without Raynaud’s phenomenon, were included in the study. IgG and IgM antiphospholipid antibodies and aβ2GPI were determined by enzyme linked immunosorbent assay (ELISA). Results: Fifty patients (54%) were positive for IgG and/or IgM antibodies to one or more phospholipid antigens or to β2GPI. The prevalence of all autoantibodies evaluated, either IgG or IgM, was higher in patients without than in those with Raynaud’s phenomenon. A negative association was found between IgG aCL and Raynaud’s phenomenon (p=0.038), whereas autoantibodies other than aCL were not significantly associated with Raynaud’s phenomenon. Conclusion: Our results demonstrate no positive association between antiphospholipid antibodies and Raynaud’s phenomenon in SLE and indicate that measurement of anti-negatively charged phospholipid antibodies other than aCL is not useful as a serological marker predictive for Raynaud’s phenomenon.
Dysphagia After Heimlich Maneuver Olenchock, Stephen A.; Rowlands, Deborah M.; Reed, James F. ...
Chest,
January 2004, 2004-Jan, 2004-01-00, 20040101, Letnik:
125, Številka:
1
Journal Article
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