From the 'Unite INSERM U 196 and 'Unite INSERM U 255. Institut Curie, 26, rue d'Ulm. 75005-Paris Poly A RNA has been isolated from a murine T cell hybridoma (TzD4) that spontaneously secretes ...suppressive immunoglobulin G-binding factor (IgGBF). Translation products, obtained from a rabbit reticulocyte lysate translation system and after injection into Xenopus Zaeuis oocytes, contain material with the biologic activity, the affinity, and the m.w. of murine IgGBF; it suppresses secondary in vitro IgG antibody production in a dose-dependent fashion. The suppressive factor binds to IgG but not to IgM immunoadsorbents and, after mild NaDodSO, treatment, dissociates in NaDodSO, polyacrylamide gels into two peaks at 78 and 40 kD. Translation products from two non-IgGBF-secreting cell lines (BW-5147, a T lymphoma line, and Ae, a fibroblast cell line) fail to exert any suppressive activity. On sucrose gradients, the RNA responsible for the bio-logic activity was found in one major peak located at 11s. IgGBF synthesized in a cellfree translation system by using poly A RNA and sucrose gradient fractions was also characterized by immunoprecip-itation with Fc fragments of 35Smethionine-labeled proteins. On NaDodSO, polyacrylamide gels, it migrates in one peak located at 37 kD. We conclude that IgGBF is coded for by 11s poly A RNA and that no post-translational modifications (other than pro-teolytic cleavage) are necessary to obtain a biologically active factor with Ig-binding properties. The production of Ig classes and subclasses by B cells is regulated by T cell factors (l) , among which immuno-globulin-binding factors (IBF)3 may play a major role (2). Produced by Fc receptor (FcR)-positive T cells, these factors bind specifically to the Fc portion of Ig and modulate the in vitro production of the corresponding Ig isotype. Three different isotype-specific T cell factors have been
Paralelos a los sillares grabados de Rasines, Cantabria García-Gelabert Pérez, María Paz
Espacio, tiempo y forma. revista de la Facultad de Geografía e Historia / Serie 2, Historia antigua,
01/1991, Letnik:
4, Številka:
4
Journal Article
Recenzirano
Odprti dostop
El objetivo de este trabajo se concreta en un sólo punto: dar a conocer paralelos a los sillares grabados, pertenecientes a los muros de la iglesia de San Andrés de Rasines. Mas antes permítaseme ...bosquejar unas notas acerca de estos sillares y del entorno en que se hallaron.
García Gelabert María Paz. Análisis comparativo entre la colonización griega en Crimea y en el sur de la península Ibérica. In: La Mer Noire zone de contacts : actes du VIIe Symposium de Vani ...(Colchide) - 26-30 IX 1994. Besançon : Institut des Sciences et Techniques de l'Antiquité, 1999. pp. 41-56. (Collection « ISTA », 715)
En este texto me ocupo de las referencias, textuales y principalmente iconográficas, sobre el culto a las aguas en las áreas tanto colonial —fenicios, griegos y púnicos— como ibérica de época ...prerromana en España. En el mundo colonial el culto a las aguas puede revestir una función múltiple —oracular, curativa, sagrada—. La iconografía es el principal medio para acercarnos a la concepción del agua en el mundo ibérico. Pero es un documento ambiguo pues los símbolos revisten múltiples significaciones según el contexto.In this paper I analyse the references —especially literary sources and iconography— dealing with the water cults in Preroman Spain. The scope of the research is limited only to the colonial áreas such as Phoenicians, Greeks and Punios and, in the second part, to the Iberian one. In the colonies this cult was endowed with a multiplicity of functions such as oracular, sacred and curatives powers. Iconography is the main way we dispose as an approach to the different notions of water amongst the Iberians. But iconography is often vague and ambiguous, for symbols have a multiplicity of contextual meanings.
Provider: - Institution: Gredos. Repositorio Documental de la Universidad de Salamanca - Data provided by Europeana Collections- ES Después de informar acerca de las peculiaridades del asentamiento ...de la cueva del Valle y de las campañas de 1996, 1997, 1998, planteamos un estudio del trabajo desarrollado sobre hueso por el grupo humano de la cueva durante el Magdaleniense Superior Final Cantábrico.- EN After informing about the peculiarities of the settlement of the Cave of the Valley and of the campaigns of 1996, 1997, 1998, expounds a study of the developed work on bone for the human group of the cave during the Cantabtic Latter Upper Magdalenian.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: Gredos. Repositorio Documental de la Universidad de Salamanca - Data provided by Europeana Collections- La religión ibérica parece ser religión de un gran pragmatismo. Las ...normas religiosas de comportamiento de todas las sociedades de tecnología simple se centran, sobre todo, en las incertidumbres de la existencia. El hombre de tales sociedades es más instintivo que el de niveles superiores, de ahí que su religión esté impregnada de un alto grado de naturalismo. Prioritariamente sus cultos son paralelos a las manifestaciones generales que constituyen la base de su vida material: el cielo, las estaciones cambiantes, los fenómenos atmosféricos, lluvias, vientos, tormentas, terremotos; la tierra y sus frutos exteriores e interiores, los animales, etc. Como escribe M. Eliade1, «en los niveles arcaicos de la cultura general de la humanidad el vivir del ser humano es ya de por sí un acto religioso, pues tomar alimento, ejercer la sexualidad y trabajar, son actos de un valor sacramental».- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
A new and more alarming source of marine contamination has been recently identified in micro and nanosized plastic fragments. Microplastics are difficult to see with the naked eye and to biodegrade ...in marine environment, representing a problem since they can be ingested by plankton or other marine organisms, potentially entering the food web. An important source of microplastics appears to be through sewage contaminated by synthetic fibres from washing clothes. Since this phenomenon still lacks of a comprehensive analysis, the objective of this contribution was to investigate the role of washing processes of synthetic textiles on microplastic release. In particular, an analytical protocol was set up, based on the filtration of the washing water of synthetic fabrics and on the analysis of the filters by scanning electron microscopy. The quantification of the microfibre shedding from three different synthetic fabric types, woven polyester, knitted polyester, and woven polypropylene, during washing trials simulating domestic conditions, was achieved and statistically analysed. The highest release of microplastics was recorded for the wash of woven polyester and this phenomenon was correlated to the fabric characteristics. Moreover, the extent of microfibre release from woven polyester fabrics due to different detergents, washing parameters and industrial washes was evaluated. The number of microfibres released from a typical 5 kg wash load of polyester fabrics was estimated to be over 6,000,000 depending on the type of detergent used. The usage of a softener during washes reduces the number of microfibres released of more than 35%. The amount and size of the released microfibres confirm that they could not be totally retained by wastewater treatments plants, and potentially affect the aquatic environment.
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•A successful procedure to evaluate microplastics release from fabrics was set up.•The amount of microplastics depends on the fabrics, laundry products and washes.•An increased amount of microfibres is released by woven polyester.•Softener and bleach reduce fibre's damage and breaks.•High temperature, washing time and mechanical action increase the microfibre release.
A successful procedure to quantify the microfibre release from synthetic fabrics was developed. The effect of detergents and washing conditions on the extent of microfibre release was evaluated.
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