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zadetkov: 25
1.
  • Inhibition of IRE1 RNase ac... Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
    Logue, Susan E; McGrath, Eoghan P; Cleary, Patricia ... Nature communications, 08/2018, Letnik: 9, Številka: 1
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    Triple-negative breast cancer (TNBC) lacks targeted therapies and has a worse prognosis than other breast cancer subtypes, underscoring an urgent need for new therapeutic targets and strategies. IRE1 ...
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  • Development of multiplex di... Development of multiplex digital PCR assays for the detection of PIK3CA mutations in the plasma of metastatic breast cancer patients
    Corné, Julien; Le Du, Fanny; Quillien, Véronique ... Scientific reports, 08/2021, Letnik: 11, Številka: 1
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    Abstract With the approval of new therapies targeting the PI3K pathway, the detection of PIK3CA mutations has become a key factor in treatment management for HR+/HER2− metastatic breast cancer (MBC). ...
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3.
  • A framework for validating ... A framework for validating AI in precision medicine: considerations from the European ITFoC consortium
    Tsopra, Rosy; Fernandez, Xose; Luchinat, Claudio ... BMC medical informatics and decision making, 10/2021, Letnik: 21, Številka: 1
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    Abstract Background Artificial intelligence (AI) has the potential to transform our healthcare systems significantly. New AI technologies based on machine learning approaches should play a key role ...
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4.
  • SARS-CoV-2 integral membran... SARS-CoV-2 integral membrane proteins shape the serological responses of patients with COVID-19
    Martin, Sophie; Heslan, Christopher; Jégou, Gwénaële ... iScience, 10/2021, Letnik: 24, Številka: 10
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    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has elicited a unique mobilization of the scientific community to develop efficient tools to understand and combat the infection. ...
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5.
  • COUP-TFI modifies CXCL12 an... COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration
    Boudot, Antoine; Kerdivel, Gwenneg; Lecomte, Sylvain ... BMC cancer, 06/2014, Letnik: 14, Številka: 1
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    The orphan receptors COUP-TF (chicken ovalbumin upstream promoter transcription factor) I and II are members of the nuclear receptor superfamily that play distinct and critical roles in vertebrate ...
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  • Impact of EPclin on adjuvan... Impact of EPclin on adjuvant therapeutic decision making and comparison of EPclin to the PREDICT tool
    Bourien, Héloïse; Quillien, Véronique; Godey, Florence ... The International journal of biological markers, 06/2021, Letnik: 36, Številka: 2
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    Purpose: Genomic signatures, such as EndoPredict®, may help clinicians to decide which adjuvant treatment is the most appropriate. Methods: We propose the EndoPredict® assay for unclear cases of ...
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7.
  • An EMT-primary cilium-GLIS2... An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis
    Wilson, Molly M; Callens, Céline; Le Gallo, Matthieu ... Science advances, 2021-Oct-29, Letnik: 7, Številka: 44
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    The epithelial-mesenchymal transition (EMT) and primary ciliogenesis induce stem cell properties in basal mammary stem cells (MaSCs) to promote mammogenesis, but the underlying mechanisms remain ...
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  • Tumor analysis: freeze-thaw... Tumor analysis: freeze-thawing cycle of triple-negative breast cancer cells alters tumor CD24/CD44 profiles and the percentage of tumor-infiltrating immune cells
    Le Gallo, Matthieu; de la Motte Rouge, Thibault; Poissonnier, Amanda ... BMC research notes, 06/2018, Letnik: 11, Številka: 1
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    The use of novel methods to characterize living tumor cells relies on well-conceived biobanks. Herein, we raised the question of whether the composition of fresh and freeze/thawed dissociated tumor ...
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  • Sentinel lymph node analysi... Sentinel lymph node analysis in breast cancer: contribution of one-step nucleic acid amplification (OSNA)
    Godey, Florence; Leveque, Jean; Tas, Patrick ... Breast cancer research and treatment, 01/2012, Letnik: 131, Številka: 2
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    One-step nucleic acid amplification (OSNA, Sysmex, Kobe, Japan) offers an excellent opportunity for accurate exhaustive sentinel lymph node (SLN) examination in breast cancer patients. Calibrated ...
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zadetkov: 25

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