This paper examines the magnitude and source of gender gaps in cognitive and social‐emotional skills in early primary grades in rural Indonesia. Relative to boys, girls score more than 0.17 SD higher ...in tests of language and mathematics (cognitive skills) and between 0.18 and 0.27 SD higher in measures of social competence and emotional maturity (social‐emotional skills). We use Oaxaca–Blinder decomposition to investigate the extent to which gender differences in early schooling and parenting practices explain these gender gaps in skills. For cognitive skills, differences in early schooling between boys and girls explain between 9% and 11% of the gender gap whereas differences in parenting practices explain merely 3%–5% of the gender gap. This decomposition result is driven largely by children living in villages with high‐quality preschools. In contrast, for social‐emotional skills, differences in parenting styles toward boys and girls explain between 13% and 17% of the gender gap, while differences in early schooling explain only 0%–6% of the gender gap.
A selection of results from Table 4 are shown. Line shows magnitude of gender gap. Point estimates are reported using black data labels. Each section of the bar shows the share of the gender gap explained. Shares are reported using white data labels. Hollow sections are statistically insignificant. A small statistically insignificant negative estimate for the share of the gap explained by months of preprimary school in the case of emotional maturity is not visible. Unpacking gender gaps in cognitive and socio‐emotional skills, this paper finds that differences in parenting styles and in early schooling play a key role in explaining gaps in achievement between boys and girls. However, relative to each other, parenting styles seem to explain more of the gap in socio‐emotional skills while schooling seems to explain more of the gap in cognitive skills.
Two new natural products, micropeptin TR1058 (
) and aeruginosin TR642 (
), were isolated from the hydrophilic extract of bloom material of
sp. collected from the Timurim water reservoir in Israel. ...The structures of compounds
and
were determined using 1D and 2D NMR spectroscopy and HR ESI MS and MS/MS techniques. Micropeptin TR1058 (
) was extremely unstable under the isolation conditions, and several degradation products were identified. NMR analysis of aeruginosin TR642 (
) revealed a mixture of eight isomers, and elucidation of its structure was challenging. Aeruginosin TR642 contains a 4,5-didehydroaraginal subunit that has not been described before. Micropeptin TR1058 (
) inhibited chymotrypsin with an IC
of 6.78 µM, and aeruginosin TR642 (
) inhibited trypsin and thrombin with inhibition concentration (IC
) values of 3.80 and 0.85 µM, respectively. The structures and biological activities of the new compounds are discussed.
Improvement of poor subgrade soils using cement kiln dust Mosa, Ahmed Mancy; Taher, Amer Hasan; Al-Jaberi, Layth A.
Case Studies in Construction Materials,
December 2017, 2017-12-00, 2017-12-01, Letnik:
7, Številka:
C
Journal Article
Recenzirano
Odprti dostop
Construction of pavements layers on subgrade with excellent to good properties reduces the thickness of the layers and consequently reduces the initial and maintenance cost of highways and vice ...versa. However, construction of pavements on poor subgrade is unavoidable due to several constrains. Improvement of subgrade properties using traditional additives such as lime and Portland cement adds supplementary costs. Therefore, using by-products in this domain involves technical, economic, and environmental advantages. Cement kiln dust (CKD) is generated in huge quantities as a by-product material in Portland cement plants. Therefore, it can be considered as an excellent alternative in this domain. In Iraq, Portland cement plants generate about 350000 tons of CKD annually which is available for free. Therefore, Iraq can be adopted as a case study. This paper covers using CKD to improve the properties of poor subgrade soils based on series of California Bearing Ration (CBR) tests on sets of untreated samples and samples treated with different doses of CKD in combination with different curing periods to investigate their effects on soil properties. The results exhibited that adding 20% of CKD with curing for 14days increases the CBR value from 3.4% for untreated soil to 48% for treated soil; it, also, decreases the swelling ratio. To determine the effects of using this dose under the mentioned curing period on the designed thicknesses of pavements layers, a case study was adopted. The case study results exhibited that treatment of the subgrade soil by 20% of CKD with curing for 14days reduces the cost of the pavements by $25.875 per square meter.
Bacterial chondronecrosis with osteomyelitis (BCO) lameness is the most critical animal health and welfare issue facing the broiler industry worldwide. It is estimated that 1 to 2% of bird ...condemnation at marketing age is caused by BCO lameness, resulting in tens of millions of dollars in annual losses. Fast-growing broilers are prone to mechanical stress that triggers bacterial translocation across epithelial barriers into the bloodstream, followed by bacterial colonization in the growth plate of long bones, and eventually, bone necrosis and lameness. Mycotoxins (MTX) are secondary metabolites produced naturally by microfungi, of which deoxynivalenol (DON), fumonisin (FUM), and zearalenone are the most prevalent in corn and soybean-meal-based diets. The presence of these mycotoxins in feed has been proven to reduce the barrier strength of the intestinal tracts and trigger immunosuppressive effects. In this study, we investigated the effects of the DON and FUM-contaminated feeds on the incidence of BCO lameness in broilers reared in both wire- and litter-floors. 720 one-day-old broiler chicks were assigned to the 2 × 2 factorial design: 2 MTX diets containing DON and FUM on wire flooring (MTX-W) and litter flooring (MTX-L), and 2 diets without MTX contamination on control wire flooring (CW) and control litter flooring (CL). Throughout the trial, the cumulative incidence of lameness per treatment was assessed by necropsying the lame birds. Birds in the MTX-W group had a higher incidence of lameness compared to those in CW (73.3% vs. 62.0%) (P < 0.05), and birds in the MTX-L group had a higher incidence of lameness compared to birds in CL (54.0% vs. 34.0%) (P < 0.05). MTX elicited net increases in BCO to a greater degree on litter (+20%) than on wire flooring (+12%). The increased incidence of BCO lameness in the MTX-W coincided with increased intestinal permeability supporting a correlation between intestinal barrier integrity and BCO lameness. To conclude, DON and FUM are predisposing factors for increasing BCO. However, no significant interaction exists between the diet and floor types in inducing lameness in broilers.
We used an embryo lethality assay (ELA) to assess virulence for different isolates from cases of bacterial chondronecrosis with osteomyelitis (BCO) in broilers. Lameness is among the most significant ...animal welfare issues in the poultry industry. Bacterial infections are a major cause of lameness and different bacterial species have been obtained from lame broilers. Reliable lab-based assays are required to assess relative virulence of bacteria obtained from lame broilers. ELA has been used to assess lethal dosage of Enterococcus faecalis and Enterococcus cecorum. We hypothesized that ELA could substitute for more laborious and costly assessments of BCO isolate pathogenicity using live birds. We evaluated 2 different levels of bacteria injected into eggs from layer and commercial broiler embryos. Significant findings include 1) Escherichia coli from neighboring farms operated by the same integrator had very different embryo lethality, 2) isolate Staphylococcus agnetis 908 had low virulence in ELA, even though this isolate can induce more than 50% BCO lameness, 3) Enterococcus cecorum 1415 also had low pathogenicity; even though it was recovered from severe bilateral tibial dyschondroplasia, 4) human and chicken BCO isolates of S. aureus had significant pathogenicity, 5) virulence for some isolates was highly variable possibly corresponding with quality of the embryos/fertile eggs used, and 6) ELA pathogenicity was much lower for our BCO isolates than previous reports which may reflect maternal environment. Overall, ELA virulence and BCO virulence are not always concordant indicating that ELA may not be an effective measure for assessing virulence with respect to BCO.
This report demonstrates that high levels of lameness can be induced by a limited bacterial challenge in drinking water for birds raised on litter flooring, comparable with lameness induced by the ...gold standard for inducing lameness, growth on suspended wire flooring. The bacterium used in the challenge was cultured from lesions in birds induced for bacterial chondronecrosis with osteomyelitis (BCO) in the wire-flooring model so the epidemiology appears similar. The litter-flooring model could better approximate broiler operations. Furthermore, the work demonstrates that 2 commercial probiotics (GalliProTect and GalliProMax) can reduce lameness in the bacterial challenge litter-flooring model. Lameness attributable to BCO is one of the most significant animal welfare issues for broiler production. The wire-flooring and litter-flooring models afford alternatives for understanding the etiology, and epidemiology of BCO, and development of management strategies to reduce lameness. Probiotics afford a promising management strategy. The results suggest that the probiotic protection may extend beyond just intestinal health and intestinal barrier function.
Angiogenesis is a major prerequisite for hepatocellular carcinoma (HCC) development and progression. The present study aims to assess the potential role of two endogenous regulators of angiogenesis ...histamine (His) and acetylcholine (Ach), as possible biochemical markers for staging of HCC. Five groups of rats were used in this study: a control healthy group (I), another 4 intoxicated groups used for the induction of HCC with a high dose of diethyl nitrosamine (DENA, 200 mg/kg, single I.P. dose), (II, III, IV, and V). Groups II, III, IV, and V were killed following 8, 16, 24, and 32 weeks after DENA injection, respectively. Serum level of His and Ach was estimated using high-performance liquid chromatography technique coupled with diode array detector (HPLC–DAD), and alpha-fetoprotein (AFP) was measured using ELISA technique along with liver histological examination for all groups. Progression of HCC was estimated by histopathological examination. The results exhibited prominent increase in serum His and Ach levels during the early stages of HCC in group II, III in comparison with the control, and then His serum level declined to the normal level during the last stage of HCC development (group V).However, Ach elevation continued. AFP serum level showed marked increase, till 32 weeks after hepatocarcinogenesis. The decreased histamine level, combined to elevated AFP, indicates an early stage, while continued elevation of Ach with decreased His levels indicates a later stage of HCC. The combination of these two neurotransmitters to AFP may contribute to a noninvasive biochemical staging for HCC.
•Children pursue a variety of pathways through early childhood education.•Household wealth, maternal education and service quality predict pathways.•A full course of early education at the right age ...is linked to higher test scores.
This paper documents that children in rural Indonesia participate in a great variety of early childhood education pathways. Three key factors predict early education pathways: household wealth, mother’s education, and the quality of available services. We also find that children who enrolled in playgroup programs at age 3–4 followed by kindergarten programs at age 5–6 scored significantly higher on primary school tests than those enrolled only in playgroup programs or only in kindergarten programs. This suggests that the sequence of these pathways is important for future learning. We also provide illustrative estimates of the cost-effectiveness of different pathways.
The feed additive Availa-ZMC was investigated for the ability to reduce lameness in broilers using 2 alternative models for inducing lameness. The mixture of organic trace minerals was effective in ...reducing lameness by 20% in the wire flooring model and 25% in the litter flooring model with the bacterial challenge. Lameness in both models is overwhelmingly attributable to bacterial chondronecrosis with osteomyelitis. The reduction in lameness was associated, at least in part, with enhanced intestinal barrier integrity mediated by elevated expression of tight junction proteins and stimulation of bactericidal killing of adherent peripheral blood monocytes obtained from the birds treated with Availa-ZMC. Lameness is a major animal welfare concern in broiler production. The wire flooring model and litter flooring model with the bacterial challenge are effective models for evaluation of management strategies for mitigating infectious causes of lameness.
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