Abstract
Background
In recent years, nucleotide sequencing has become increasingly instrumental in both research and clinical settings. This has led to an explosive growth in sequencing data produced ...worldwide. As the amount of data increases, so does the need for automated solutions for data processing and analysis. The concept of workflows has gained favour in the bioinformatics community, but there is little in the scientific literature describing end-to-end automation systems. Arteria is an automation system that aims at providing a solution to the data-related operational challenges that face sequencing core facilities.
Findings
Arteria is built on existing open source technologies, with a modular design allowing for a community-driven effort to create plug-and-play micro-services. In this article we describe the system, elaborate on the underlying conceptual framework, and present an example implementation. Arteria can be reduced to 3 conceptual levels: orchestration (using an event-based model of automation), process (the steps involved in processing sequencing data, modelled as workflows), and execution (using a series of RESTful micro-services). This creates a system that is both flexible and scalable. Arteria-based systems have been successfully deployed at 3 sequencing core facilities. The Arteria Project code, written largely in Python, is available as open source software, and more information can be found at https://arteria-project.github.io/
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Conclusions
We describe the Arteria system and the underlying conceptual framework, demonstrating how this model can be used to automate data handling and analysis in the context of a sequencing core facility.
Our study shows if and how Swedish public service television has changed its content from the time when SVT had monopoly until this day when the competition is greater than ever. We got an insight in ...what has been presented to the audience by studying TV schedules from 1975 to 2009. The study examines four weeks during the years when the two main channels SVT1 and SVT2 have been broadcasting. One week each of these following years have been examined: 1975, 1985, 1995 and 2009. These years have been chosen to get an insight in what content the TV schedules presented before and after SVT got competition in the Swedish TV market. A total of 28 days and 56 TV schedules have been examined. This was done with a quantitative analysis and with an own model of ten categories that has helped us to sort the TV shows based on their content. Even though it was not a great difference, the result shows that the percentage of news has decreased since 1975. But it was not possible to see if the TV shows that replaced the news in the TV schedule was of an entertaining kind. The study also shows that a new kind of TV shows have taken a large spot in the schedules. Nowadays it is common that a TV show mix different kind of categories during its broadcasting time. One example is Gomorron Sverige. Furthermore we have seen that live debates take a large place in the TV schedules in 2009, especially during the day time. Besides that, the sizes of the categories have been pretty even during the 34 years. SVT has not made any significant changes since the monopoly was broken and the competition became a reality. We have also noticed that the broadcasting time has increased a lot since 1975. It is particularly obvious in the day time where there many years ago were no broadcasting at all. Our main purpose with the study was to examine if there is less news today in favour of TV shows of a more entertaining kind.
The Pedagogical progression within MSI – Based upon The Bologna Process and UPC. In a near future several of the European countries will begin working after new guidelines concerning a declaration ...called the Bologna process. Everything will be done one step at a time and the declaration will change the way the students are being graded, all this for the sake of making the European labour-market more opened for all of its millions of students. In Växjö this process is in the making, but to adapt to the future demands the school must also change its ways of teaching. To increase its quality the University has put together a procedure of actions to improve the pedagogical working method in all its institutions. In this essay we would like to elucidate how the work with the Bologna process is proceeding within the institution of Mathematics and System Engineering and what they do improve their pedagogical teaching. By doing a qualitative case study on the student at the Computer Science Program we wish to find the answers to our questions.
Det pedagogiska arbetet inom MSI – Utifrån Bolognaprocessen och UPC. Inom en snar framtid kommer flertalet länder i Europa jobba efter nya riktlinjer enligt en deklaration kallad Bolognaprocessen. Det hela kommer att ske i etapper och innebär att sättet på vilket studenter bedöms kommer ändras, allt för att göra Europas arbetsmarknad öppnare för alla dess miljoner studerande. I Växjö pågår detta arbete för fullt, men för att anpassa sig till framtida krav måste skolan även förändra sin utbildningsform. För att höja sin kvalité har universitetet tagit fram en handlingsplan för att förbättra de pedagogiska arbetsmetoderna i alla institutioner. I den här uppsatsen vill vi belysa hur arbetet med Bolognaprocessen fortgår inom Matematiska och systemtekniska institutionen och vad de gör för att förbättra den pedagogiska undervisningen. Genom att göra en kvalitativ undersökning med Systemvetenskapliga programmets studenter försöker vi finna svaren på våra frågor.
Den 20 november 1989 antog Sverige tillsammans med de flesta andra regeringar i världen FN:s konvention om barnets rättigheter. Tio år senare har det arbetats fram en strategi för att implementera ...Barnkonventionen i högre utbildning och då med en tyngdpunkt på de utbildningar som riktar sig mot yrken som berör barn. Exempel på sådana utbildningar är sjuksköterske-, socionom- och lärarutbildningen. Vi har intresserat oss särskilt för lärarutbildningen. Demokratifrågor och utbildningsfrågor är i dagsläget högst aktuella på den politiska agendan, inte minst genom skolministerns ambition att kvalitetssäkra grundskolan. Vi har i denna uppsats för avsikt att beskriva en teoretisk demokratimodell, som är uttalat eftersträvansvärd i svensk politik, och med hjälp av den och Barnkonventionen, undersöka och problematisera framtida lärares kompetens i barnrätt. Vårt arbete koncentrerar sig på de olika ställningstaganden lärarstudenter tar i figurerade situationer där barnets rättigheter riskerar att åsidosättas. Metoden vi valt för detta är att genom en självskattningsenkät utfå ett representativt urval av lärarstudenter, vilka intervjuas i fallstudier. 24 utsagor från lärarstudenter har legat till grund för analys och tolkning. Läsaren kommer att få ta del av några karaktäristika, av den lärare som vi enligt undersökningen uppfattar som den vanligaste förekommande i dilemman som berör demokrati- och barnrättsfrågor. Men också hur den ideala läraren kan komma att gestalta sig ur ett deltagardemokratiskt och barnrättsperspektiv.
Detta examensarbete har genomförts i samarbete med ALMI Företagspartner AB som arbetar med att främja utveckling av företag och nyföretagande. Tillsammans med Landstinget i Jönköpings län driver de ...projektet P.U.M.A, Produktutveckling med Medicinsk Anknytning Examensarbetet omfattar utveckling av ett skydd till en trevägskran. Skyddets syfte är att förhindra ofrivillig justering av de kranar som används vid intravenös infusion av cytostatika, då patienten behandlas i hemmet. Vid behandling flödar cytostatikan genom en trevägskran. Kranen monteras på patienten, som har hudkontakt med denna under hela behandlingen. I den teoretiska bakgrunden beskrivs metoder för produktutveckling och en rad återkommande begrepp i rapporten. Vid genomförandet gjordes inledningsvis en marknadsundersökning, vilken utgjorde underlag för produktkraven. Efter idégenerering genomfördes sållning i två faser för att sortera bort koncept som ej uppfyllde ställda krav. Sållningen följdes upp med tillverkning av enkla prototyper, vilka utvärderades och låg till grund för val av slutgiltigt koncept. Examensarbetet resulterade i ett färdigt koncept som uppfyller de krav som ställdes med avseende på funktion, säkerhet, pris och miljö. Vid eventuell massproduktion av produkten kommer ytterligare tester och finjustering av konstruktionen krävas.
In today’s modern society with high-speed connections covering the globe people are more than ever finding themselves gazing into the cold lights of the computer screen. On the other side a strange ...and exciting world yet to be explored awaits. Many are those who spend hour after hour running over green hills swimming in vast blue oceans in the lands of Azeroth, the playfield in the MMORPG game World of Warcraft. In media we often read and hear alarming reports on players stuck in this virtual world, ceasing to play a part in the real world. This thesis will make an attempt as to hear what those who play the game has to say in the matter. Through interviews we’ll try to separate or combine media’s view of the game from that of those who play it.
Background Traditional banks monopolized financial services, but the 2008 crisis spurred Fintech's emergence as an alternative. Fintech challenges banks with innovative solutions, while Sweden ...thrives as a Fintech hub. Profitability is vital due to the recent shift in focus from growth. Modern Fintech research is lacking, thus creating gaps in both knowledge and studies among the Swedish Fintech-sphere. Purpose The study analyzes leverage, return on equity, and bank size ratios in Swedish Fintech companies. It examines their impact on profit margin and aims to identify correlations. The results aim to enhance understanding and provide guidance for optimizing key figures to increase profitability among Swedish Fintech-companies. Methodology The study utilized a quantitative approach with a deductive method and cross-sectional design. Data consisted of secondary data and was collected through the database Retriever Business. A total of 1198 observations were analyzed using correlation matrix, bivariate, and multivariate regression analyses. Results The quantitative analysis revealed that both debt to equity ratio and return on equity has a significant relationship, while bank size has only a partially significant relationship with profit margin. Conclusion Swedish Fintech-companies reveals a positive relationship between return on equity (ROE) and profitability. Furthermore, the leverage ratio also positively affects profitability. Moreover, Bank size shows a slight negative impact.
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