Neutrinophilic axion-like dark matter Huang, Guo-yuan; Nath, Newton
The European physical journal. C, Particles and fields,
11/2018, Letnik:
78, Številka:
11
Journal Article
Recenzirano
Odprti dostop
The axion-like particles (ALPs) are very good candidates of the cosmological dark matter, which can exist in many extensions of the standard model (SM). The mass of the ALPs can be as small as
O
(
10
...-
22
)
eV
. On the other hand, the neutrinos are found to be massive and the SM must be extended to explain the sub-eV neutrino masses. It becomes very interesting to consider an exclusive coupling between these two low scale frontiers that are both beyond the SM. The propagation of neutrinos inside the Milky Way would undergo the coherent forward scattering effect with the ALP background, and the neutrino oscillation behavior can be modified by the ALP-induced potential. Assuming a derivative coupling between the ALP and the three generations of active neutrinos, possible impacts on the neutrino oscillation experiments have been explored in this paper. In particular, we have numerically studied the sensitivity of the deep underground neutrino experiment (DUNE). The astrophysical consequences of such coupling have also been investigated systematically.
In light of the exciting campaign of cosmogenic neutrino detection, we investigate the double and multiple tau bangs detectable at future tau neutrino telescopes. Such events are expected from the ...Standard Model (SM) higher-order processes, which can be easily identified with broad techniques anticipated at future tau neutrino telescopes. We find that SM perturbative processes can already contribute observable double-bang events to telescopes with a sensitivity of collecting
O
(
100
)
cosmogenic neutrino events. The detectable but suppressed rate in fact makes the double and multiple bangs an excellent probe of SM unknowns and possible new physics beyond. As a case study, the nonperturbative sphaleron process, which can copiously produce multiple tau bangs, is explored.
A
bstract
In the near future, the neutrinoless double-beta (0
νββ
) decay experiments will hopefully reach the sensitivity of a few meV to the effective neutrino mass |
m
ββ
|. In this paper, we ...tentatively examine the sensitivity of future 0
νββ
-decay experiments to neutrino masses and Majorana CP phases by following the Bayesian statistical approach. Provided experimental setups corresponding to the experimental sensitivity of |
m
ββ
| ≃ 1 meV, the null observation of 0
νββ
decays in the case of normal neutrino mass ordering leads to a very competitive bound on the lightest neutrino mass
m
1
. Namely, the 95% credible interval in the Bayesian approach turns out to be 1
.
6 meV ≲
m
1
≲ 7
.
3 meV or 0
.
3 meV ≲
m
1
≲ 5
.
6 meV when the uniform prior on
m
1
/
eV or on log
10
(
m
1
/
eV) is adopted. Moreover, one of two Majorana CP phases is strictly constrained, i.e., 140° ≲
ρ
≲ 220° for both scenarios of prior distributions of
m
1
. In contrast, if a relatively worse experimental sensitivity of |
m
ββ
| ≃ 10 meV is assumed, the constraint on the lightest neutrino mass becomes accordingly 0
.
6 meV ≲
m
1
≲ 26 meV or 0 ≲
m
1
≲ 6
.
1 meV, while two Majorana CP phases will be essentially unconstrained. In the same statistical framework, the prospects for the determination of neutrino mass ordering and the discrimination between Majorana and Dirac nature of massive neutrinos in the 0
νββ
-decay experiments are also discussed. Given the experimental sensitivity of |
m
ββ
| ≃ 10 meV (or 1 meV), the strength of evidence to exclude the Majorana nature under the null observation of 0
νββ
decays is found to be inconclusive (or strong), no matter which of two priors on
m
1
is taken.
Single-cell RNA sequencing (scRNA-seq) technologies are poised to reshape the current cell-type classification system. However, a transcriptome-based single-cell atlas has not been achieved for ...complex mammalian systems. Here, we developed Microwell-seq, a high-throughput and low-cost scRNA-seq platform using simple, inexpensive devices. Using Microwell-seq, we analyzed more than 400,000 single cells covering all of the major mouse organs and constructed a basic scheme for a mouse cell atlas (MCA). We reveal a single-cell hierarchy for many tissues that have not been well characterized previously. We built a web-based “single-cell MCA analysis” pipeline that accurately defines cell types based on single-cell digital expression. Our study demonstrates the wide applicability of the Microwell-seq technology and MCA resource.
Display omitted
•Development of Microwell-seq, a high-throughput and low-cost scRNA-seq platform•Construction of a single-cell mouse cell atlas (scMCA) covering major cell types•Characterization of cellular heterogeneity with minimal batch effect•Characterization of cross-tissue cellular network at the single-cell level
Development of Microwell-seq allows construction of a mouse cell atlas at the single-cell level with a high-throughput and low-cost platform.
Recent studies have highlighted super-enhancers (SEs) as important regulatory elements for gene expression, but their intrinsic properties remain incompletely characterized. Through an integrative ...analysis of Hi-C and ChIP-seq data, here we find that a significant fraction of SEs are hierarchically organized, containing both hub and non-hub enhancers. Hub enhancers share similar histone marks with non-hub enhancers, but are distinctly associated with cohesin and CTCF binding sites and disease-associated genetic variants. Genetic ablation of hub enhancers results in profound defects in gene activation and local chromatin landscape. As such, hub enhancers are the major constituents responsible for SE functional and structural organization.
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