Interspecific hybridization with ‘Satputia’ (bisexual and cluster bearing) can be highly useful for the introgression of cluster bearing, high yield and gynoecism in sponge gourd (monoecious and ...solitary bearing). However, the occurrence of self-pollination in closed flowers and anthesis of two species at different time intervals creates hindrance in interspecific hybridization. The present investigation highlighted that the reciprocal interspecific cross (Satputia × sponge gourd) is more successful for development of F
1
hybrid and its further utilization in development of segregating generations. Pre-anthesis emasculation (28 h before anthesis) of Satputia buds in the evening and pollination with sponge gourd (PSG-9) in the morning on the day of anthesis resulted in high fruit set. Interspecific hybrids were monoecious and morphologically intermediate for most of the vegetative, flower and fruit traits. The seed of hybrid vines was vigorous than both the parents with respect to size and weight. Ample pollen production, pollen viability and high fruit set on selfing confirmed the fertility status of vines. Although pollen size was less than both the parents, but the pollen density improved in F
1
vines. Fertile hybrids could be easily used to generate F
2
and BC
1
P
2
and TCH segregating generations. In F
2
generation, gynoecious, adroecious, andromonoecoius, monoecious and cluster bearing vines of variable length and fruit size were observed. In back cross and triple cross generations, most of the vines were monoecious except a few adroecious and gynoecious with improved fruit size, vine growth and bearing capacity. Backcross and triple cross with sponge gourd displayed a shift towards this species.
Heterotopic sites of pleomorphic adenoma Kaur, Jasmeen; Kaur, Manmeet
Journal of family medicine and primary care,
05/2023, Letnik:
12, Številka:
5
Journal Article
Recenzirano
Odprti dostop
The majority of the tumours occurring in minor salivary glands are malignant with only 18% being benign. Among the benign tumours, pleomorphic adenoma is the most common. Although it presents more ...commonly in the parotid and submandibular glands, it can occur at any site where salivary glands reside. Only 6.4% of cases of pleomorphic adenoma occur in minor salivary glands, e.g. palate, cheeks, lips, para-pharyngeal space, etc. It occurs in females in the fourth or fifth decade. It presents as an asymptomatic and slow-growing mass. The treatment of choice is wide local excision due to the high rate of recurrence and malignant potential. We present rare case reports of two patients. The first case is of a young 18 years female presenting with recurrent neck (anterior triangle) swelling and the second case is of a 46-year-old female presenting with lower lip swelling. In both cases, it was a slow-growing mass and asymptomatic. Cytological examination of the lesion revealed the diagnosis of pleomorphic adenoma. It was completely excised with no post-operative complication. Pleomorphic adenoma, although a common benign neoplasm of major salivary glands, should always be kept as a possibility at the locations of minor salivary glands. As pleomorphic adenoma can transform into a malignant counterpart, therefore early diagnosis and treatment of the lesion can prevent further complications. The prognosis of pleomorphic adenoma is excellent. However, a close follow-up of the patient is required due to the high rate of recurrence.
The universal spread of novel virus named coronavirus disease 2019 (COVID-19) also known as 2019-nCoV, Middle East Respiratory Syndrome and severe acute respiratory syndrome coronavirus 2 ...(SARS-CoV-2) declared by the world health organisation (WHO). This virus has dived in to multiorgan, with clinical manifestations of fever, sore throat, dry cough, dyspnoea, chest pain, nausea, vomiting, diarrhoea and muscle pain. As novel coronavirus been categorised as HG3 infection which has highest with inhalation and by skin surface contact. As previous pandemics have occurred like SARS and MERS special attention to autopsy had been given to prevent exposure to the healthcare workers. Similar attention should be given to the autopsy protocols and underlying pathology for COVID-19 infection so as to better understanding of the disease for further control and treatment guidelines. Thus, herein we bring and summarise review of literature for understanding.
The corpse plant (Amorphophallus titanum) is so named because it produces a pungent, foul odor when flowering. Little is known about how the emitted volatiles change throughout the two-day flowering ...period. In this study, the comprehensive monitoring of the presence and change in volatile molecules during the female and the male flowering phases of A. titanum was conducted, and the plant temperature was monitored. A total of 422 volatile features were detected over the entire sampling period, of which 118 features were statistically significantly different between the pre-flowering and both flowering phases, and an additional 304 features were found present throughout the flowering period. A total of 45 molecules could be assigned putative names. The volatile profile of A. titanum changes over the two-day flowering period, with the S-containing molecules and aldehydes dominant in the female flowering phase, and the alcohols and hydrocarbons dominant in the male flowering phase. The two-dimensional gas chromatography time-of-flight mass spectrometry (GC × GC-TOFMS) enabled us to identify 32 new molecules produced by A. titanum. Each of these molecules alone, and in combination, likely contribute to the different odors emitted during the flowering phase of A. titanum.
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Silver nanoparticles play a significant role in biomedical sciences due to their unique properties allowing for their use as an effective sensing and remediation platform Herein, the ...green synthesis of silver nanostructures (Ag NSs), prepared via aqueous extract of waste Brassica oleracea leaves in the presence of silver nitrate solution (10-4 M), is reported. The Ag NSs are fully characterized and their efficacy with respect to 4-nitrophenol reduction, glucose sensing, and microbes is determined. Visually, the color of silver nitrate containing solution altered from colorless to yellowish, then reddish grey, confirming the formation of Ag NSs. HRTEM and SEAD studies revealed the Ag NSs to have different morphologies (triangular, rod-shaped, hexagonal, etc., within a size range of 20–40 nm) with face-centered cubic (fcc) crystal structure. The Ag NSs possess high efficacy for nitrophenol reduction (<11 min and degradation efficiency of 98.2%), glucose sensing (LOD: 5.83 µM), and antimicrobial activity (E. coli and B. subtilis with clearance zones of 18.3 and 14 mm, respectively). Thus, the current study alludes towards the development of a cost-effective, sustainable, and efficient three-in-one platform for biomedical and environmental applications.
The release of heavy metals into the environment has surged, due to rapid industrialization and urbanization globally, which causes. contamination of air, water, and soil. These persistent and ...bioaccumulative metals (lead, mercury, cadmium, and arsenic) pose major risks to both human health and the ecological balance. Therefore, heavy metal pollution emerges as a daunting challenge in contemporary times, Carbon dots (CDs) have attracted significant attention in recent years due to their potential applications in sensing heavy metal ions. Many conventional chemical methods have been used for the synthesis of CDs, however, these methods possess many shortcomings such as noxious byproducts, harsh chemicals, high cost, etc. To diminish these shortcomings, green chemistry plays a significant role in the preparation of CDs. Thus, it is very imperative to explore the green synthesis methodologies for the preparation of CDs over conventional ones. The article delves into a comprehensive bibliometric analysis of the green synthesis methods CDs for heavy metal ion sensing applications in the period between 2003-2024. Additionally, we have also provided an overview of the mechanism behind the green synthesis of CDs by exploring the role of phytoconstitutes present in natural resources. Furthermore, the sensing mechanism of CDs toward heavy metal ions is also explored. This review compiles the bibliometric analysis and synthesis process with various materials used for the detection of heavy metals.
The exceptional antibacterial properties of silver nanoparticles (Ag NPs) and their prospective uses in different fields have attracted a lot of interest in contemporary times. The chemical agents ...used in the preparation of Ag NPs are hazardous to human health and the environment. In contrast to chemical approaches, green synthesis techniques involve the use of natural resources, which accomplish the principles of green chemistry and sustainable development goals (SDGs). In this regard, this review article delves into a comprehensive analysis of the green synthesis methods employed for the production of Ag NPs and their utilization as diverse antimicrobial agents. In addition to exploring the many antimicrobial uses of Ag NPs production, this article attempts to give a thorough examination of the processes behind the antibacterial activity of Ag NPs. This review provides in-depth mechanisms of antimicrobial action, including rupture of membranes, production of reactive oxygen species (ROS), and disruption of cellular functions. Thus, this article explores recent insights into green synthesis approaches for the preparation of Ag NPs which are effectively utilized as antimicrobial agents.
Early and accurate diagnosis of oral cancer is important to reduce the mortality rate in patients. Point-of-care (POC) detection of oral cancer biomarkers has emerged as an effective means of ...early-stage diagnosis. Cytokines, particularly, interleukin-6 (IL-6) and interleukin-8 (IL-8), have been repeatedly implicated as potential biomarkers capable of differentially diagnosing benign oral lesions from malignant ones. The first part of this review describes the structure and function of both IL-6 and IL-8, followed by their specific role in the development of oral cancer. The second part of the review discusses the emerging biosensor platforms for the POC detection of IL-6 and IL-8. The different optical and electrochemical biosensors developed so far for the detection of IL-6 and IL-8 have been summarized with recent literature reports. Additionally, the integration of nanotechnology-based strategies for enhanced sensitivity and multiplexing is also emphasized. Finally, the challenges involved in the translation of these POC biosensors into clinical practices for oral cancer detection are discussed herein, along with future perspectives.
•Structural and functional characteristics of IL-6 and IL-8 and their role as biomarkers for early detection of oral cancer.•Various POC biosensing platforms fabricated to detect IL-6 and IL-8 in early diagnosis of oral cancer.•Design, fabrication, transduction mechanisms of optical and electrochemical biosensors for POC detection of IL-6 and IL-8.•Challenges involved in analyzing real samples using these biosensors and their translation into clinical practices.
In recent years, the field of green synthesis for carbon dots has seen significant advancements in the development of materials for heavy metal ion sensing applications. A variety of eco-friendly and ...sustainable approaches have been explored to synthesize carbon dots (CDs) with enhanced sensing properties. These materials have shown great promise in detecting heavy metal ions due to their high sensitivity, selectivity, and low detection limits One of the key advancements in this area is the utilization of natural sources such as biomass, organic waste, and plant extracts as precursors for the synthesis of CDs. These green precursors not only contribute to the sustainable nature of the synthesis process but also result in the production of carbon dots with unique surface chemistry and optical properties. In addition to the synthesis and functionalization strategies, the understanding of the underlying mechanisms governing the interaction between CDs and heavy metal ions has advanced significantly. This improved understanding has facilitated the design of CDs with tailored sensing capabilities and improved overall performance. Overall, the recent progress in the green synthesis of CDs for heavy metal ion sensing holds great promise for the development of cost-effective, environmentally friendly, and high-performance sensing platforms with potential applications in environmental monitoring, industrial safety, and healthcare diagnostics.
