We present fully covered phased light curves for 56 Jovian Trojan asteroids as observed by the K2 mission of the Kepler space telescope. This set of objects has been monitored during Campaign 6 and ...represents a nearly unbiased subsample of the population of small solar system bodies. We derived precise periods and amplitudes for all Trojans, and found their distributions to be compatible with the previous statistics. We point out, however, that ground-based rotation periods are often unreliable above 20 h, and we find an overabundance of rotation periods above 60 h compared with other minor planet populations. From amplitude analysis we derive a rate of binarity of 20 ± 5%. Our spin rate distribution confirms the previously obtained spin barrier of ~5 h and the corresponding ~0.5 g cm-3 cometary-like density limit, also suggesting a high internal porosity for Jovian Trojans. One of our targets, asteroid 65227 exhibits a double rotation period, which can either be due to binarity or the outcome of a recent collision.
We present the metallicity results from the ARGOS spectroscopic survey of the Galactic bulge. Our aim is to understand the formation of the Galactic bulge: did it form via mergers, as expected from Λ ...cold dark matter theory, or from disc instabilities, as suggested by its boxy/peanut shape, or both? Our stars are mostly red clump giants, which have a well-defined absolute magnitude from which distances can be determined. We have obtained spectra for 28 000 stars at a spectral resolution of R = 11 000. From these spectra, we have determined stellar parameters and distances to an accuracy of <1.5 kpc. The stars in the inner Galaxy span a large range in Fe/H, −2.8 ≤ Fe/H ≤ +0.6. From the spatial distribution of the red clump stars as a function of Fe/H, we propose that the stars with Fe/H > −0.5 are part of the boxy/peanut bar/bulge. We associate the lower metallicity stars (Fe/H < −0.5) with the thick disc, which may be puffed up in the inner region, and with the inner regions of the metal-weak thick disc and inner halo. For the bulge stars with Fe/H > −0.5, we find two discrete populations: (i) stars with Fe/H −0.25 which provide a roughly constant fraction of the stars in the latitude interval b = −5° to −10°, and (ii) a kinematically colder, more metal-rich population with mean Fe/H +0.15 which is more prominent closer to the plane. The changing ratio of these components with latitude appears as a vertical abundance gradient of the bulge. We attribute both of these bulge components to instability-driven bar/bulge formation from the thin disc. We associate the thicker component with the stars of the early less metal-rich thin disc, and associate the more metal-rich population concentrated to the plane with the colder more metal-rich stars of the early thin disc, similar to the colder and younger more metal-rich stars seen in the thin disc in the solar neighbourhood today. We do not exclude a weak underlying classical merger-generated bulge component, but see no obvious kinematic association of any of our bulge stars with such a classical bulge component. The clear spatial and kinematic separation of the two bulge populations (i) and (ii) makes it unlikely that any significant merger event could have affected the inner regions of the Galaxy since the time when the bulge-forming instabilities occurred.
Context. Because the second reaction wheel failed, a new mission was conceived for the otherwise healthy Kepler space telescope. In the course of the K2 mission, the telescope is staring at the plane ...of the Ecliptic. Thousands of solar system bodies therefore cross the K2 fields and usually cause additional noise in the highly accurate photometric data. Aims. We here follow the principle that some person’s noise is another person’s signal and investigate the possibility of deriving continuous asteroid light curves. This is the first such endeavor. In general, we are interested in the photometric precision that the K2 mission can deliver on moving solar system bodies. In particular, we investigate space photometric optical light curves of main-belt asteroids. Methods. We studied the K2 superstamps that cover the fields of M35, and Neptune together with Nereid, which were observed in the long-cadence mode (29.4 min sampling). Asteroid light curves were generated by applying elongated apertures. We used the Lomb-Scargle method to determine periodicities that are due to rotation. Results. We derived K2 light curves of 924 main-belt asteroids in the M35 field and 96 in the path of Neptune and Nereid. The light curves are quasi-continuous and several days long. K2 observations are sensitive to longer rotational periods than typical ground-based surveys. Rotational periods are derived for 26 main-belt asteroids for the first time. The asteroid sample is dominated by faint objects (>20 mag). Owing to the faintness of the asteroids and the high density of stars in the M35 field, only 4.0% of the asteroids with at least 12 data points show clear periodicities or trends that signal a long rotational period, as opposed to 15.9% in the less crowded Neptune field. We found that the duty cycle of the observations had to reach ~60% to successfully recover rotational periods.
Research gaps in understanding flood changes at the catchment scale caused by changes in forest management, agricultural practices, artificial drainage, and terracing are identified. Potential ...strategies in addressing these gaps are proposed, such as complex systems approaches to link processes across time scales, long‐term experiments on physical‐chemical‐biological process interactions, and a focus on connectivity and patterns across spatial scales. It is suggested that these strategies will stimulate new research that coherently addresses the issues across hydrology, soil and agricultural sciences, forest engineering, forest ecology, and geomorphology.
Plain Language Summary
This commentary explores research gaps in the field of land use change impacts on floods at the catchment scale and proposes possible ways forward for addressing these gaps. Specifically the impacts of forest management, agricultural practices, artificial drainage, and terracing on flood generation at the catchment scale are explored. Potential strategies in addressing research gaps in these fields are complex systems approaches to link processes across time scales, long‐term experiments on physical‐chemical‐biological process interactions, and a focus on connectivity and patterns across spatial scales. It is suggested that these strategies will stimulate new research that coherently addresses the issues across hydrology, soil and agricultural sciences, forest engineering, forest ecology, and geomorphology.
Key Points
Land use change impacts on floods are poorly understood at the catchment scale
Numerous synergies are identified in exploring the effects of changed agricultural practices, artif. drainage, terracing, and forest cover
A cross‐disciplinary systems approach aided by long‐term field studies and a focus on flow connectivity are needed to make major advances
Main-belt Asteroids in the K2 Uranus Field Molnár, L.; Pál, A.; Sárneczky, K. ...
The Astrophysical journal. Supplement series,
02/2018, Letnik:
234, Številka:
2
Journal Article
Recenzirano
Odprti dostop
We present the K2 light curves of a large sample of untargeted main-belt asteroids (MBAs) detected with the Kepler Space Telescope. The asteroids were observed within the Uranus superstamp, a ...relatively large, continuous field with a low stellar background designed to cover the planet Uranus and its moons during Campaign 8 of the K2 mission. The superstamp offered the possibility of obtaining precise, uninterrupted light curves of a large number of MBAs and thus determining unambiguous rotation rates for them. We obtained photometry for 608 MBAs, and were able to determine or estimate rotation rates for 90 targets, of which 86 had no known values before. In an additional 16 targets we detected incomplete cycles and/or eclipse-like events. We found the median rotation rate to be significantly longer than that of the ground-based observations, indicating that the latter are biased toward shorter rotation rates. Our study highlights the need and benefits of further continuous photometry of asteroids.
We present the kinematic results from our ARGOS spectroscopic survey of the Galactic bulge of the Milky Way. Our aim is to understand the formation of the Galactic bulge. We examine the kinematics of ...about 17 400 stars in the bulge located within 3.5 kpc of the Galactic Centre, identified from the 28 000 star ARGOS survey. We aim to determine if the formation of the bulge has been internally driven from disc instabilities as suggested by its boxy shape, or if mergers have played a significant role as expected from lambda cold dark matter simulations. From our velocity measurements across latitudes b = −5°, − 7
5 and −10° we find the bulge to be a cylindrically rotating system that transitions smoothly out into the disc. From observations of 3 fields at b = +10, the kinematics of the bulge show North-South symmetry about the major axis. Within the bulge, we find a kinematically distinct metal-poor population (Fe/H < −1.0) that is not rotating cylindrically. The 5 per cent of our stars with Fe/H < −1.0 are a slowly rotating spheroidal population, which we believe are stars of the metal-weak thick disc and halo which presently lie in the inner Galaxy. The kinematics of the two bulge components that we identified in ARGOS Paper III (mean Fe/H −0.25 and Fe/H +0.15, respectively) demonstrate that they are likely to share a common formation origin and are distinct from the more metal-poor populations of the thick disc and halo which are co-located inside the bulge. We do not exclude an underlying merger generated bulge component but our results favour bulge formation from instabilities in the early thin disc.
Cytotoxic chemotherapy can be very effective for the treatment of cancer but toxicity on normal tissues often limits patient tolerance and often causes long-term adverse effects. The objective of ...this study was to assist in the preclinical development of using modified, non-living bacterially-derived minicells to deliver the potent chemotherapeutic doxorubicin via epidermal growth factor receptor (EGFR) targeting. Specifically, this study sought to evaluate the safety and efficacy of EGFR targeted, doxorubicin loaded minicells (designated EGFRminicellsDox) to deliver doxorubicin to spontaneous brain tumors in 17 companion dogs; a comparative oncology model of human brain cancers.
EGFRminicellsDox were administered weekly via intravenous injection to 17 dogs with late-stage brain cancers. Biodistribution was assessed using single-photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI). Anti-tumor response was determined using MRI, and blood samples were subject to toxicology (hematology, biochemistry) and inflammatory marker analysis. Targeted, doxorubicin-loaded minicells rapidly localized to the core of brain tumors. Complete resolution or marked tumor regression (>90% reduction in tumor volume) were observed in 23.53% of the cohort, with lasting anti-tumor responses characterized by remission in three dogs for more than two years. The median overall survival was 264 days (range 49 to 973). No adverse clinical, hematological or biochemical effects were observed with repeated administration of EGFRminicellsDox (30 to 98 doses administered in 10 of the 17 dogs).
Targeted minicells loaded with doxorubicin were safely administered to dogs with late stage brain cancer and clinical activity was observed. These findings demonstrate the strong potential for clinical applications of targeted, doxorubicin-loaded minicells for the effective treatment of patients with brain cancer. On this basis, we have designed a Phase 1 clinical study of EGFR-targeted, doxorubicin-loaded minicells for effective treatment of human patients with recurrent glioblastoma.
The Diels-Alder reaction is a cornerstone in organic synthesis, forming two carbon-carbon bonds and up to four new stereogenic centers in one step. No naturally occurring enzymes have been shown to ...catalyze bimolecular Diels-Alder reactions. We describe the de novo computational design and experimental characterization of enzymes catalyzing a bimolecular Diels-Alder reaction with high stereoselectivity and substrate specificity. X-ray crystallography confirms that the structure matches the design for the most active of the enzymes, and binding site substitutions reprogram the substrate specificity. Designed stereoselective catalysts for carbon-carbon bond-forming reactions should be broadly useful in synthetic chemistry.
Context. With seven planets, the TRAPPIST-1 system has among the largest number of exoplanets discovered in a single system so far. The system is of astrobiological interest, because three of its ...planets orbit in the habitable zone of the ultracool M dwarf. Aims. We aim to determine interior structures for each planet and estimate the temperatures of their rock mantles due to a balance between tidal heating and convective heat transport to assess their habitability. We also aim to determine the precision in mass and radius necessary to determine the planets’ compositions. Methods. Assuming the planets are composed of uniform-density noncompressible materials (iron, rock, H2O), we determine possible compositional models and interior structures for each planet. We also construct a tidal heat generation model using a single uniform viscosity and rigidity based on each planet’s composition. Results. The compositions for planets b, c, d, and e remain uncertain given the error bars on mass and radius. With the exception of TRAPPIST-1c, all have densities low enough to indicate the presence of significant H2O. Planets b and c experience enough heating from planetary tides to maintain magma oceans in their rock mantles; planet c may have surface eruptions of silicate magma, potentially detectable with next-generation instrumentation. Tidal heat fluxes on planets d, e, and f are twenty times higher than Earth’s mean heat flow. Conclusions. Planets d and e are the most likely to be habitable. Planet d avoids the runaway greenhouse state if its albedo is ≳0.3. Determining the planet’s masses within ~0.1–0.5 Earth masses would confirm or rule out the presence of H2O and/or iron. Understanding the geodynamics of ice-rich planets f, g, and h requires more sophisticated modeling that can self-consistently balance heat production and transport in both rock and ice layers.
In this paper, we present an analysis of K2 mission Campaign 3 observations of the irregular Neptune satellite, Nereid. We determined a rotation period of P = 11.594±0.017 h and amplitude of Δm = 0
...$.\!\!\!^{{\mathrm{m}}}$
0328±0
$.\!\!\!^{{\mathrm{m}}}$
0018, confirming previous short rotation periods obtained in ground-based observations. The similarities of light-curve amplitudes between 2001 and 2015 show that Nereid is in a low-amplitude rotation state nowadays and it could have been in a high-amplitude rotation state in the mid-1960s. Another high-amplitude period is expected in about 30 yr. Based on the light-curve amplitudes observed in the last 15 yr, we could constrain the shape of Nereid and obtained a maximum a:c axis ratio of 1.3:1. This excludes the previously suggested very elongated shape of a:c ≈ 1.9:1 and clearly shows that Nereid's spin axis cannot be in forced precession due to tidal forces. Thermal emission data from the Spitzer Space Telescope and the Herschel Space Observatory indicate that Nereid's shape is actually close to the a:c axis ratio limit of 1.3:1 we obtained, and it has a very rough, highly cratered surface.