A purity monitoring system for the H1 liquid argon calorimeter Barrelet, E.; Andrieu, B.; Babaev, A. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
09/2002, Letnik:
490, Številka:
1
Journal Article
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The ionization probes used for monitoring the liquid argon purity in the H1 calorimeter are described and results of their operation in tests at CERN and during the period 1992 to the end of 1998 at ...HERA are given. The high sensitivity of the charge measurements leads to refined charge collection models, and to the observation of a variation of the ionization yield of our electron sources with temperature.
IEEE Trans.Nucl.Sci.48:1276-1285,2001 After 2001 the upgraded ep collider HERA will provide an about five times
higher luminosity for the two experiments H1 and ZEUS. In order to cope with
the ...expected higher event rates the H1 collaboration is building a track based
trigger system, the Fast Track Trigger (FTT). It will be integrated in the
first three levels (L1-L3) of the H1 trigger scheme to provide higher
selectivity for events with charged particles. The FTT will allow to
reconstruct 3-dimensional tracks in the central drift chamber down to 100 MeV/c
within the L2 latency of ~ 23 mus. To reach the necessary momentum resolution
of ~ 5% (at 1 GeV/c) sophisticated reconstruction algorithms have to be
implemented using high density Field Programmable Gate Arrays (FPGA) and their
embedded Content Addressable Memories (CAM). The final track parameter
optimization will be done using non-iterative fits implemented in DSPs. While
at the first trigger level rough track information will be provided, at L2
tracks with high resolution are available to form trigger decisions on
topological and other track based criteria like multiplicities and momenta. At
the third trigger level a farm of commercial processor boards will be used to
compute physics quantities such as invariant masses.
Nucl.Instrum.Meth. A373 (1996) 387-405 A fast second level trigger has been developed for the ARGUS experiment which
recognizes tracks originating from the interaction region. The processor
compares ...the hits in the ARGUS Micro Vertex Drift Chamber to 245760 masks
stored in random access memories. The masks which are fully defined in three
dimensions are able to reject tracks originating in the wall of the narrow
beampipe of 10.5\,mm radius.
After 2001 the upgraded ep collider HERA will provide an about five times higher luminosity for the two experiments H1 and ZEUS. In order to cope with the expected higher event rates the H1 ...collaboration is building a track based trigger system, the Fast Track Trigger (FTT). It will be integrated in the first three levels (L1-L3) of the H1 trigger scheme to provide higher selectivity for events with charged particles. The FTT will allow to reconstruct 3-dimensional tracks in the central drift chamber down to 100 MeV/c within the L2 latency of ~ 23 mus. To reach the necessary momentum resolution of ~ 5% (at 1 GeV/c) sophisticated reconstruction algorithms have to be implemented using high density Field Programmable Gate Arrays (FPGA) and their embedded Content Addressable Memories (CAM). The final track parameter optimization will be done using non-iterative fits implemented in DSPs. While at the first trigger level rough track information will be provided, at L2 tracks with high resolution are available to form trigger decisions on topological and other track based criteria like multiplicities and momenta. At the third trigger level a farm of commercial processor boards will be used to compute physics quantities such as invariant masses.
A fast second level trigger has been developed for the ARGUS experiment which recognizes tracks originating from the interaction region. The processor compares the hits in the ARGUS Micro Vertex ...Drift Chamber to 245760 masks stored in random access memories. The masks which are fully defined in three dimensions are able to reject tracks originating in the wall of the narrow beampipe of 10.5\,mm radius.
Childhood Sexual Abuse and Lifetime Aggression Norton-Baker, Mara; Wolff, Jenna M.; Kolander, Tyler W. ...
Journal of child sexual abuse,
08/2019, Letnik:
28, Številka:
6
Journal Article
Recenzirano
This study of college undergraduates (N = 873) examined three hypotheses regarding associations between childhood sexual abuse and lifetime aggression: 1) childhood sexual abuse was expected to ...account for unshared variance in the lifetime aggression indicators after controlling for the potential effects of parental physical abuse, sibling physical abuse, exposure to intimate partner violence, peer bullying, and respondent age; 2) childhood sexual abuse associations were expected to be relatively stronger among the women than the men; 3) childhood sexual abuse links to lifetime aggression were expected to vary as a function of age of victimization (adolescent < childhood < dual-age victims). Aggression histories varied widely with over 20% reporting prior injuries inflicted on others (3.2% > five injuries). Sexual abuse links to aggression tended to be stronger (p < .001) for the women than the men, and rates of aggression were higher when sexual abuse recurred across both childhood and adolescence. Partial support was found for all three hypotheses.
Genome editing in induced pluripotent stem cells is currently hampered by the laborious and expensive nature of identifying homology-directed repair (HDR)-modified cells. We present an approach where ...isolation of cells bearing a selectable, HDR-mediated editing event at one locus enriches for HDR-mediated edits at additional loci. This strategy, called co-targeting with selection, improves the probability of isolating cells bearing HDR-mediated variants and accelerates the production of disease models.
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•Increases the efficiency of genome editing in human iPSCs•Enhances detectability of variants of interest derived by homology-directed repair•Is a simple, scalable, and adaptable strategy for knocking in variants of interest
The potential of CRISPR/Cas9-based genome editing in iPSCs is currently hampered by the laborious nature of identifying cells modified by the lesser-used homology-directed repair (HDR) pathway. Geurts, McDermott-Roe, and colleagues present a straightforward approach, co-targeting with selection, based on co-modification that enriches for cells undergoing HDR thereby improving targeting efficiencies.
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