The Internet has revolutionized the manner in which patients obtain information about health care. This technology has also allowed patients to obtain directly both prescription and nonprescription ...therapies.
To report a case of fulminant hepatorenal failure associated with the use of hydrazine sulfate, an unregulated alternative remedy for cancer marketed on the Internet.
Case report.
Academic medical center.
A 55-year-old man with maxillary sinus cancer.
Self-medication with hydrazine sulfate.
Serum liver and renal function tests; histologic evaluation of liver and kidney tissue.
The patient developed hepatic encephalopathy, renal failure, and profound coagulopathy. He died after severe gastrointestinal hemorrhage developed. Autopsy revealed autolysis of the kidneys and submassive bridging necrosis of the liver.
Fatal hepatorenal failure may occur after the use of hydrazine sulfate. This fatal complication must be considered in anyone taking or contemplating the use of hydrazine sulfate.
We have investigated the diffusion coefficient of nano-meter-sized domains on a vesicle composed of saturated phospholipids, unsaturated phospholipids and cholesterols by means of neutron spin echo ...spectroscopy. The obtained diffusion coefficient was examined from a viewpoint of the hydrodynamic model of Brownian objects in a fluid membrane.
We have investigated the effects of a guest component (polymer or spherical colloidal particle) confined between flexible lamellar slits on the inter-lamellar interaction by means of a small-angle ...X-ray scattering technique and a neutron spin echo technique. The dominant interaction between flexible lamellar membranes without guest components is the Helfrich mechanism. The addition of a neutral polymer into the lamellar phase induces an attractive inter-lamellar interaction and finally destabilizes the lamellar phase. On the other hand, spherical colloidal particles confined between flexible lamellar membranes reduce the undulational fluctuations of lamellae and bring a repulsive inter-lamellar interaction. The behavior of the layer compression modulus of the lamellar membrane containing colloidal particles is well described by the entropical repulsive inter-lamellar interaction driven by steric hindrance.
NEWAGE Nakamura, K; Miuchi, K; Tanimori, T ...
Journal of physics. Conference series,
01/2013, Letnik:
469, Številka:
1
Journal Article
Recenzirano
Odprti dostop
NEWAGE (New generation WIMP search with an Advanced Gaseous tracking device Experiment) is one of the direction-sensitive dark matter search experiments with a gaseous timeprojection chamber. In this ...paper, we will report results of recent underground measurements, performancesof our new detector, improvements of head-tail analysis.
Biomimetic membranes in contact with a planar substrate or a second membrane are studied theoretically. The membranes contain specific adhesion molecules (stickers) which are attracted by the second ...surface. In the absence of stickers, the trans-interaction between the membrane and the second surface is assumed to be repulsive at short separations. It is shown that the interplay of specific attractive and generic repulsive interactions can lead to the formation of a potential barrier. This barrier induces a line tension between bound and unbound membrane segments which results in lateral phase separation during adhesion. The mechanism for adhesion-induced phase separation is rather general, as is demonstrated by considering two distinct cases involving: i) stickers with a linear attractive potential, and ii) stickers with a short-ranged square-well potential. In both cases, membrane fluctuations reduce the potential barrier and, therefore, decrease the tendency of phase separation.
Background In both Brugada syndrome (BS) and arrhythmogenic right ventricular cardiomyopathy (ARVC), electrical abnormalities in the right ventricular outflow tract (RVOT) are important for ...arrhythmogenesis.
Objectives The aim of this study was to compare conduction delay in the right ventricular in BS with that in ARVC using the signal-averaged electrocardiogram.
Methods Twenty patients with BS (18 men and 2 women; 55 ± 12 years old; 9 symptomatic and 11 asymptomatic) and eight patients with ARVC (six men and two women; 53 ± 16 years old) were included. We assessed the presence of late potentials (LPs) and the filtered QRS duration (fQRSd) in V2 and V5 using a high-pass filter of 40 Hz (fQRSd:40) and 100 Hz (fQRSd:100).
Results In ARVC, there was no significant difference in fQRSd:40 between V2 and V5 (158 ± 19 vs. 145 ± 17 ms, respectively): however, in BS, fQRSd:40 in V2 was significantly longer than fQRSd:40 in V5 (147 ± 15 vs. 125 ± 10 ms, P < 0.001). In ARVC, there was no significant difference between fQRSd:40 and fQRSd:100 in V2 and V5 (158 ± 19 vs. 142 ± 23 ms and 145 ± 17 vs. 132 ± 9 ms, respectively). In contrast, in BS, fQRSd:100 was significantly shorter than fQRSd:40 in V2 (110 ± 8 ms vs. 147 ± 15, P < 0.001). The relative decrease in fQRSd:100 compared with fQRSd:40 in V2 was significantly greater in BS than in ARVC.
Conclusion The dominant prolongation of the fQRSd in the right precordial lead in BS was different from the characteristics of ARVC, which may be caused by the conduction delay due to fibro-fatty replacement in RV.
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