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zadetkov: 419
1.
  • Large-scale metabolomic pro... Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease
    Ganna, Andrea; Salihovic, Samira; Sundström, Johan ... PLOS genetics, 12/2014, Letnik: 10, Številka: 12
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    Analyses of circulating metabolites in large prospective epidemiological studies could lead to improved prediction and better biological understanding of coronary heart disease (CHD). We performed a ...
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2.
  • Genetic variance estimation... Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
    Yang, Jian; Bakshi, Andrew; Zhu, Zhihong ... Nature genetics, 10/2015, Letnik: 47, Številka: 10
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    We propose a method (GREML-LDMS) to estimate heritability for human complex traits in unrelated individuals using whole-genome sequencing data. We demonstrate using simulations based on whole-genome ...
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3.
  • Genome-wide Association Stu... Genome-wide Association Study of Susceptibility Loci for Cervical Cancer
    DAN CHEN; JUKO-PECIREP, Ivana; GYLLENSTEN, Ulf ... JNCI : Journal of the National Cancer Institute, 05/2013, Letnik: 105, Številka: 9
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    Cervical carcinoma has a heritable genetic component, but the genetic basis of cervical cancer is still not well understood. We performed a genome-wide association study of 731 422 single nucleotide ...
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4.
  • The risk of switch to mania in patients with bipolar disorder during treatment with an antidepressant alone and in combination with a mood stabilizer
    Viktorin, Alexander; Lichtenstein, Paul; Thase, Michael E ... The American journal of psychiatry, 10/2014, Letnik: 171, Številka: 10
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    This study examined the risk of antidepressant-induced manic switch in patients with bipolar disorder treated either with antidepressant monotherapy or with an antidepressant in conjunction with a ...
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5.
  • Meta-GWAS Accuracy and Powe... Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies
    de Vlaming, Ronald; Okbay, Aysu; Rietveld, Cornelius A ... PLOS genetics, 01/2017, Letnik: 13, Številka: 1
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    Large-scale genome-wide association results are typically obtained from a fixed-effects meta-analysis of GWAS summary statistics from multiple studies spanning different regions and/or time periods. ...
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6.
  • Genetic Architectures of Ch... Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct
    Ferreira, Manuel A.R.; Mathur, Riddhima; Vonk, Judith M. ... American journal of human genetics, 04/2019, Letnik: 104, Številka: 4
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    The extent to which genetic risk factors are shared between childhood-onset (COA) and adult-onset (AOA) asthma has not been estimated. On the basis of data from the UK Biobank study (n = 447,628), we ...
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7.
  • The Risk of Treatment-Emerg... The Risk of Treatment-Emergent Mania With Methylphenidate in Bipolar Disorder
    Viktorin, Alexander; Rydén, Eleonore; Thase, Michael E ... The American journal of psychiatry, 04/2017, Letnik: 174, Številka: 4
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    The authors sought to determine the risk of treatment-emergent mania associated with methylphenidate, used in monotherapy or with a concomitant mood-stabilizing medication, in patients with bipolar ...
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8.
  • Heritability of Perinatal D... Heritability of Perinatal Depression and Genetic Overlap With Nonperinatal Depression
    Viktorin, Alexander; Meltzer-Brody, Samantha; Kuja-Halkola, Ralf ... The American journal of psychiatry, 02/2016, Letnik: 173, Številka: 2
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    The authors investigated the relative importance of genetic and environmental influences on perinatal depression, and the genetic overlap between perinatal depression and nonperinatal depression. ...
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9.
  • The frailty index is a pred... The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards: a large cohort study
    Li, Xia; Ploner, Alexander; Karlsson, Ida K ... BMC medicine, 05/2019, Letnik: 17, Številka: 1
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    Frailty index (FI) is a well-established predictor of all-cause mortality, but less is known for cause-specific mortality and whether familial effects influence the associations. Middle-aged ...
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10.
  • Strategies and issues in th... Strategies and issues in the detection of pathway enrichment in genome-wide association studies
    Hong, Mun-Gwan; Pawitan, Yudi; Magnusson, Patrik K. E ... Human genetics, 08/2009, Letnik: 126, Številka: 2
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    A fundamental question in human genetics is the degree to which the polygenic character of complex traits derives from polymorphism in genes with similar or with dissimilar functions. The many ...
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zadetkov: 419

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