Context.
Markarian 501 (Mrk 501) is a very high-energy (VHE) gamma-ray blazar located at
z
= 0.034, which is regularly monitored by a wide range of multi-wavelength instruments, from radio to VHE ...gamma rays. During a period of almost two weeks in July 2014, the highest X-ray activity of Mrk 501 was observed in ∼14 years of operation of the
Neil Gehrels Swift
Gamma-ray Burst Observatory.
Aims.
We characterize the broadband variability of Mrk 501 from radio to VHE gamma rays during the most extreme X-ray activity measured in the last 14 years, and evaluate whether it can be interpreted within theoretical scenarios widely used to explain the broadband emission from blazars.
Methods.
The emission of Mrk 501 was measured at radio with Metsähovi, at optical–UV with KVA and
Swift
/UVOT, at X-ray with
Swift
/XRT and
Swift
/BAT, at gamma ray with
Fermi
-LAT, and at VHE gamma rays with the FACT and MAGIC telescopes. The multi-band variability and correlations were quantified, and the broadband spectral energy distributions (SEDs) were compared with predictions from theoretical models.
Results.
The VHE emission of Mrk 501 was found to be elevated during the X-ray outburst, with a gamma-ray flux above 0.15 TeV varying from ∼0.5 to ∼2 times the Crab nebula flux. The X-ray and VHE emission both varied on timescales of 1 day and were found to be correlated. We measured a general increase in the fractional variability with energy, with the VHE variability being twice as large as the X-ray variability. The temporal evolution of the most prominent and variable segments of the SED, characterized on a day-by-day basis from 2014 July 16 to 2014 July 31, is described with a one-zone synchrotron self-Compton model with variations in the break energy of the electron energy distribution (EED), and with some adjustments in the magnetic field strength and spectral shape of the EED. These results suggest that the main flux variations during this extreme X-ray outburst are produced by the acceleration and the cooling of the high-energy electrons. A narrow feature at ∼3 TeV was observed in the VHE spectrum measured on 2014 July 19 (MJD 56857.98), which is the day with the highest X-ray flux (>0.3 keV) measured during the entire
Swift
mission. This feature is inconsistent with the classical analytic functions to describe the measured VHE spectra (power law, log-parabola, and log-parabola with exponential cutoff) at more than 3
σ
. A fit with a log-parabola plus a narrow component is preferred over the fit with a single log-parabola at more than 4
σ
, and a dedicated Monte Carlo simulation estimated the significance of this extra component to be larger than 3
σ
. Under the assumption that this VHE spectral feature is real, we show that it can be reproduced with three distinct theoretical scenarios: (a) a pileup in the EED due to stochastic acceleration; (b) a structured jet with two-SSC emitting regions, with one region dominated by an extremely narrow EED; and (c) an emission from an IC pair cascade induced by electrons accelerated in a magnetospheric vacuum gap, in addition to the SSC emission from a more conventional region along the jet of Mrk 501.
Ovarian cancer: lymph node metastases Balbi, G; Manganaro, M A; Monteverde, A ...
European journal of gynaecological oncology,
2009, Letnik:
30, Številka:
3
Journal Article
Recenzirano
To analyze pelvic and paraaortic lymph node involvement in epithelial ovarian cancer.
Between 1995 and 2006, 60 patients with FIGO Stages II, III, IV epithelial ovarian cancer underwent surgical ...treatment, including systematic pelvic and paraaortic lymphadenectomy.
Aortic lymph node metastases were documented in 45 (75%) patients and pelvic nodal metastases in 42 (70%). The incidence of paraaortic nodal involvement was 20% (12/60) in the absence of positive pelvic nodes while the incidence of pelvic nodal involvement was 15% (9/60) in the absence of paraaortic disease; both pelvic and paraaortic lymph node involvement occurred in 55% of patients. The most frequent groups for nodal metastases are paracaval (56%), externaliliac (60%), and obturator (55%).
The rate of nodal involvement is important in ovarian cancer and there is a high prevalence of both pelvic and paraaortic lymph node metastases. For this reason bilateral pelvic and paraaortic lymphadenectomy is necessary for staging and as treatment for micrometastases, also in patients with unilateral tumors.
It is known the fusion cross section plays crucial role in the choice of the reaction to synthesize new superheavy elements. An estimation of the fusion cross section in the reactions with massive ...nuclei is difficult task when the mass (charge) and angular distributions of the quasifission and fusion-fission fragments strongly overlap. The measured yields of evaporation residues, fusion-fission and quasifission fragments in the 48Ca+154Sm reactions are analyzed in the framework of the method based on the dinuclear system concept and advanced statistical model. The experimental data of the fission fragments are decomposed into contributions coming from fusion-fission, quasifission, and fast fission. Our investigations showed the synthesis of the new element Z=120 (A=302) is more preferable in the 54Cr+248Cm reaction in comparison with the 58Fe + 244Pu and 64Ni+238U reactions because the excitation function of the evaporation residues of the former reaction is some orders of magnitude larger than that for the last two reactions.
We report the detection of pulsed gamma-ray emission from the Geminga pulsar (PSR J0633+1746) between 15 GeV and 75 GeV. This is the first time a middle-aged pulsar has been detected up to these ...energies. Observations were carried out with the MAGIC telescopes between 2017 and 2019 using the low-energy threshold Sum-Trigger-II system. After quality selection cuts, ∼80 h of observational data were used for this analysis. To compare with the emission at lower energies below the sensitivity range of MAGIC, 11 years of
Fermi
-LAT data above 100 MeV were also analysed. From the two pulses per rotation seen by
Fermi
-LAT, only the second one,
P
2, is detected in the MAGIC energy range, with a significance of 6.3
σ
. The spectrum measured by MAGIC is well-represented by a simple power law of spectral index Γ = 5.62 ± 0.54, which smoothly extends the
Fermi
-LAT spectrum. A joint fit to MAGIC and
Fermi
-LAT data rules out the existence of a sub-exponential cut-off in the combined energy range at the 3.6
σ
significance level. The power-law tail emission detected by MAGIC is interpreted as the transition from curvature radiation to Inverse Compton Scattering of particles accelerated in the northern outer gap.
We report on observations of the pulsar/Be star binary system PSR J2032+4127/MT91 213 in the energy range between and with the Very Energetic Radiation Imaging Telescope Array and Major Atmospheric ...Gamma Imaging Cherenkov telescope arrays. The binary orbit has a period of approximately 50 years, with the most recent periastron occurring on 2017 November 13. Our observations span from 18 months prior to periastron to one month after. A new point-like gamma-ray source is detected, coincident with the location of PSR J2032+4127/MT91 213. The gamma-ray light curve and spectrum are well characterized over the periastron passage. The flux is variable over at least an order of magnitude, peaking at periastron, thus providing a firm association of the TeV source with the pulsar/Be star system. Observations prior to periastron show a cutoff in the spectrum at an energy around . This result adds a new member to the small population of known TeV binaries, and it identifies only the second source of this class in which the nature and properties of the compact object are firmly established. We compare the gamma-ray results with the light curve measured with the X-ray Telescope on board the Neil Gehrels Swift Observatory and with the predictions of recent theoretical models of the system. We conclude that significant revision of the models is required to explain the details of the emission that we have observed, and we discuss the relationship between the binary system and the overlapping steady extended source, TeV J2032+4130.
A case of neurofibroma is reported in a wild striped mullet Mugil cephalus. Macro‐ and microscopic features are described. The tumor arose on the head as a white–grayish, firm mass protruding ...outwards but covered by the epidermis. The neoplastic tissue showed well‐defined borders and was encapsulated; it was predominantly composed of elongated cells with ellipsoid, hyperchromatic nuclei and pale cytoplasm. The cells were irregularly arranged; in the context of the neoplastic proliferation, these cells were usually densely packed, sometimes forming parallel arrays, but without distinctive nuclear palisades. The diagnosis of neurofibroma is also supported by the positive immunostaining for S‐100 and vimentin as well as by the negative calretinin reaction.
Context. PKS 1510–089 is a flat spectrum radio quasar strongly variable in the optical and GeV range. To date, very high-energy (VHE, > 100 GeV) emission has been observed from this source either ...during long high states of optical and GeV activity or during short flares. Aims. We search for low-state VHE gamma-ray emission from PKS 1510–089. We characterize and model the source in a broadband context, which would provide a baseline over which high states and flares could be better understood. Methods. PKS 1510–089 has been monitored by the MAGIC telescopes since 2012. We use daily binned Fermi-LAT flux measurements of PKS 1510–089 to characterize the GeV emission and select the observation periods of MAGIC during low state of activity. For the selected times we compute the average radio, IR, optical, UV, X-ray, and gamma-ray emission to construct a low-state spectral energy distribution of the source. The broadband emission is modeled within an external Compton scenario with a stationary emission region through which plasma and magnetic fields are flowing. We also perform the emission-model-independent calculations of the maximum absorption in the broad line region (BLR) using two different models. Results. The MAGIC telescopes collected 75 hr of data during times when the Fermi-LAT flux measured above 1 GeV was below 3 × 10−8 cm−2 s−1, which is the threshold adopted for the definition of a low gamma-ray activity state. The data show a strongly significant (9.5σ) VHE gamma-ray emission at the level of (4.27 ± 0.61stat) × 10−12 cm−2 s−1 above 150 GeV, a factor of 80 lower than the highest flare observed so far from this object. Despite the lower flux, the spectral shape is consistent with earlier detections in the VHE band. The broadband emission is compatible with the external Compton scenario assuming a large emission region located beyond the BLR. For the first time the gamma-ray data allow us to place a limit on the location of the emission region during a low gamma-ray state of a FSRQ. For the used model of the BLR, the 95% confidence level on the location of the emission region allows us to place it at a distance > 74% of the outer radius of the BLR.
Context.
Certain types of supernova remnants (SNRs) in our Galaxy are assumed to be PeVatrons, capable of accelerating cosmic rays (CRs) to ~ PeV energies. However, conclusive observational evidence ...for this has not yet been found. The SNR G106.3+2.7, detected at 1–100 TeV energies by different γ-ray facilities, is one of the most promising PeVatron candidates. This SNR has a cometary shape, which can be divided into a head and a tail region with different physical conditions. However, in which region the 100 TeV emission is produced has not yet been identified because of the limited position accuracy and/or angular resolution of existing observational data. Additionally, it remains unclear as to whether the origin of the γ-ray emission is leptonic or hadronic.
Aims.
With the better angular resolution provided by new MAGIC data compared to earlier
γ
-ray datasets, we aim to reveal the acceleration site of PeV particles and the emission mechanism by resolving the SNR G106.3+2.7 with 0.1° resolution at TeV energies.
Methods.
We observed the SNR G106.3+2.7 using the MAGIC telescopes for 121.7 h in total – after quality cuts – between May 2017 and August 2019. The analysis energy threshold is ~0.2 TeV, and the angular resolution is 0.07−0.1°. We examined the
γ
-ray spectra of different parts of the emission, whilst benefitting from the unprecedented statistics and angular resolution at these energies provided by our new data. We also used measurements at other wavelengths such as radio, X-rays, GeV
γ
-rays, and 10 TeV
γ
-rays to model the emission mechanism precisely.
Results.
We detect extended γ-ray emission spatially coincident with the radio continuum emission at the head and tail of SNR G106.3+2.7. The fact that we detect a significant
γ
-ray emission with energies above 6.0 TeV from only the tail region suggests that the emissions above 10 TeV detected with air shower experiments (Milagro, HAWC, Tibet AS
γ
and LHAASO) are emitted only from the SNR tail. Under this assumption, the multi-wavelength spectrum of the head region can be explained with either hadronic or leptonic models, while the leptonic model for the tail region is in contradiction with the emission above 10 TeV and X-rays. In contrast, the hadronic model could reproduce the observed spectrum at the tail by assuming a proton spectrum with a cutoff energy of ~1 PeV for that region. Such high-energy emission in this middle-aged SNR (4−10 kyr) can be explained by considering a scenario where protons escaping from the SNR in the past interact with surrounding dense gases at present.
Conclusions.
The
γ
-ray emission region detected with the MAGIC telescopes in the SNR G106.3+2.7 is extended and spatially coincident with the radio continuum morphology. The multi-wavelength spectrum of the emission from the tail region suggests proton acceleration up to ~PeV, while the emission mechanism of the head region could either be hadronic or leptonic.
We report on the detection of flaring activity from the Fanaroff-Riley I radio galaxy NGC 1275 in very-high-energy (VHE, E > 100 GeV) gamma rays with the Major Atmospheric Gamma Imaging Cherenkov ...(MAGIC) telescopes. The observations were performed between 2016 September and 2017 February, as part of a monitoring programme. The brightest outburst, with ∼1.5 times the Crab Nebula flux above 100 GeV (C.U.), was observed during the night between 2016 December 31 and 2017 January 1. The flux is fifty times higher than the mean flux previously measured in two observational campaigns between 2009 October and 2010 February and between 2010 August and 2011 February. Significant variability of the day-by-day light curve was measured. The shortest flux-doubling timescale was found to be of (611 ± 101) min. The spectra calculated for this period are harder and show a significant curvature with respect to the ones obtained in the previous campaigns. The combined spectrum of the MAGIC data during the strongest flare state and simultaneous data from the Fermi-LAT around 2017 January 1 follows a power law with an exponential cutoff at the energy (492 ± 35) GeV. We further present simultaneous optical flux density measurements in the R-band obtained with the Kungliga Vetenskaps Akademien (KVA) telescope and investigate the correlation between the optical and gamma-ray emission. Due to possible internal pair-production, the fast flux variability constrains the Doppler factor to values that are inconsistent with a large viewing angle as observed in the radio band. We investigate different scenarios for the explanation of fast gamma-ray variability, namely emission from magnetospheric gaps, relativistic blobs propagating in the jet (mini-jets), or an external cloud (or star) entering the jet. We find that the only plausible model to account for the luminosities here observed would be the production of gamma rays in a magnetospheric gap around the central black hole, only in the eventuality of an enhancement of the magnetic field threading the hole from its equipartition value with the gas pressure in the accretion flow. The observed gamma-ray flare therefore challenges all the discussed models for fast variability of VHE gamma-ray emission in active galactic nuclei.
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