At the end of the Second World War the United Nations gave to Italy a special protectorate on the own former colony by the International Trusteeship System of Somalia, which concludes in 1960. During ...the Fifties there are many relationships between the italian men and the somali women: from these liaisons there are a lot of children which have different destinies and their history represents one of the heredity of the italian past in Africa. From this italo-somali métissage, rises an association who asks the recognition of all the pains suffered by a part of that community and in the same time it asks a collective reflections of the historic memories about the Trusteeship System.
Circulating T cells, which migrate from the periphery to sites of tissue inflammation, play a crucial role in the development of various chronic inflammatory conditions. Recent research has ...highlighted subsets of tissue-resident T cells that acquire migratory capabilities and re-enter circulation, referred to here as “recirculating T cells.” In this review, we examine recent advancements in understanding the biology of T cell trafficking in diseases where T cell infiltration is pivotal, such as multiple sclerosis and inflammatory bowel diseases, as well as in metabolic disorders where the role of T cell migration is less understood. Additionally, we discuss current insights into therapeutic strategies aimed at modulating T cell circulation across tissues and the application of state-of-the-art technologies for studying recirculation in humans. This review underscores the significance of investigating T trafficking as a novel potential target for therapeutic interventions across a spectrum of human chronic inflammatory diseases.
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Components of the immune system; Human metabolism; Immunology; Physiology.
Al termine della Seconda Guerra Mondiale le Nazioni Unite affidano all’Italia il protettorato sulla propria ex colonia mediante lo strumento dell’Amministrazione Fiduciaria Italiana della Somalia ...(AFIS) che termina nel 1960. Durante gli anni Cinquanta le relazioni tra uomini italiani e donne somale sono numerose: da queste unioni nasce una prole meticcia che ha destini differenti e la cui vicenda rappresenta una delle eredità del passato italiano in Africa. Da questo meticciato italo-somalo sorge un’associazione che chiede il riconoscimento di tutte le sofferenze subite da una parte della comunità meticcia e allo stesso tempo preme per una riflessione collettiva sulla memoria storica del periodo dell’AFIS.
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