The Implicit Positive and Negative Affect Test (IPANAT) is an instrument for the indirect assessment of positive and negative affect. A Japanese version of the IPANAT was developed and its ...reliability and validity were examined. In Study 1, factor analysis identified two independent factors that could be interpreted as implicit positive and negative affect, which corresponded to the original version. The Japanese IPANAT also had sufficient internal consistency and acceptable test–retest reliability. In Study 2, we demonstrated that the Japanese IPANAT was associated with explicit state affect (e.g., PANAS), extraversion, and neuroticism, which indicated its adequate construct validity. In Study 3, we examined the extent to which the Japanese IPANAT was sensitive to changes in affect by assessing a set of IPANAT items after the presentation of positive, negative, or neutral photographs. The results indicated that the Japanese IPANAT was sufficiently sensitive to changes in affect resulting from affective stimuli. Taken together, these studies suggest that the Japanese version of the IPANAT is a useful instrument for the indirect assessment of positive and negative affect.
目的：本研究の目的は，高齢糖尿病患者における転倒歴と閉じこもりとの関連性を検討することである．方法：対象は伊勢赤十字病院外来通院中の65歳以上の糖尿病患者とした．外出頻度が一日に一回未満の場合を閉じこもりと定義し，また過去一年間の転倒歴の有無を調査した．従属変数を閉じこもり，説明変数を転倒歴及び調整因子（年齢，性別，糖尿病罹病期間，HbA1c，心血管疾患，認知・生活機能低下，うつ，独居，孤立，及び糖尿病治療）としたロジスティック回帰分析を用いて転倒歴の閉じこもりに関する調整後オッズ比を算出した．結果：564例（男性319例，女性245例）が本研究の解析対象となった．転倒歴あり及び閉じこもり該当者はそれぞれ198人（35.1%），88人（15.6%）であった．転倒歴の閉じこもりに関する調整後オッズ比は2.69（95% confidence interval，1.31 to 5.52；P=0.007）であった．結論：本研究において，転倒歴は閉じこもりに有意に関連した．転倒歴を有する高齢糖尿病患者を診た際の閉じこもりへの注意喚起が重要と考えられた．
A solitary fibrous tumor (SFT) is a rare spindle-cell mesenchymal neoplasm, which frequently occurs in the pleural cavity and rarely in extrapleural sites. SFT of the central nervous system was first ...reported in 1996, and since then, more than 200 cases have been reported in the literature. We herein report a case of intracranial SFT extending supra/infratentorially. There are only ten similar cases reported in the literature. A 49-year-old female with a two-month history of disequilibrium was referred to our hospital. Contrast-enhanced magnetic resonance imaging (MRI) showed a right tentorial tumor extending supra/infratentorially, which was homogeneously enhanced. Right external carotid angiography showed intense tumor staining fed by the occipital artery. Under a preoperative diagnosis of tentorial meningioma, the tumor was removed with combined right suboccipital/occipital craniotomy after embolization of the feeding artery. The histopathological diagnosis was SFT. The patient’s postoperative course was uneventful, and her symptoms were completely resolved. Although intracranial SFT is poorly recognized and its preoperative diagnosis is still challenging, SFT should be included in the differential diagnosis of extra-axial tumors extending supra/infratentorially.
目的：サルコペニア合併高齢糖尿病患者に対する多面的治療プログラムの，筋力，身体機能，及び骨格筋量への影響を検証すること．方法：伊勢赤十字病院，糖尿病代謝内科に通院している65歳以上の糖尿病患者を対象とした．サルコペニアの診断はAsian Working Group for Sarcopenia ...2019を元に行った．四肢骨格筋量の測定は多周波生体電気インピーダンス法，筋力は握力，身体機能は5回椅子立ち上がり検査でそれぞれ評価した．多面的治療プログラム（蛋白質摂取量の適正化，レジスタンストレーニング，及びサルコペニアに関する患者教育）開始前と12週後に，筋力，身体機能，四肢骨格筋指数，及びその他パラメーターを評価し，前後比較した．統計処理には対応のあるt検定を用いた．結果：14例（男性3人，女性11人）が本研究の解析対象となった．平均年齢は74.4±4.7歳であった．多面的治療プログラムにより，握力（男性：23.2±5.6 kgから25.6±5.5 kg，P=0.014，女性：15.5±5.0 kgから18.9±5.0 kg，P＜0.001），及び5回椅子立ち上がりテスト（11.2±2.5秒から8.6±1.7秒，P＝0.002）の有意な改善を認めた．また，HbA1c（8.1±0.7%から7.7±0.9%，P＝0.004）の有意な低下も認められた．一方，四肢骨格筋指数の増加傾向はあったものの有意差は認めなかった．結論：サルコペニア合併高齢糖尿病患者に対する多面的治療プログラムにより，筋力及び身体機能の改善が認められた．
Background: Serum CA15-3 has been one of the most reliable tumor markers used in monitoring breast cancer patients; however, its sensitivity in detecting metastases is limited. To increase its ...sensitivity, the combined measurement of other tumor markers with CA15-3 was investigated. Methods: Serum CA15-3, carcinoembryonic antigen (CEA) and sialyl Lewis X (CSLEX) were simultaneously measured in a prospective series of 455 postoperative breast cancer patients with or without metastasis. The diagnostic parameters sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy for detecting metastases were compared. The correlation of values between pairs of tumor markers was analyzed. The efficacy of combined measurement of two different tumor markers was also evaluated. Results: The sensitivity for detecting metastases was 61.5, 56.9 and 52.3%; specificity was 97.2, 93.6 and 96.2%; PPV was 78.4, 59.7 and 69.4%; NPV was 93.8, 92.9 and 92.4%; and accuracy was 92.1, 88.8 and 89.9% for CA15-3, CEA and CSLEX, respectively. The values for CA15-3 were significantly correlated with those for CEA (P < 0.001) but not those for CSLEX. The combined measurement of CSLEX and CA15-3 increased the sensitivity by 17.0% but that of CEA and CA15-3 increased the sensitivity by only 10.8%. All diagnostic parameters for the combined measurement of CSLEX and CA15-3 were higher than those for the combined measurement of CEA and CA15-3. Conclusions: These findings suggest that CSLEX may be more useful than CEA in combination with CA15-3 in monitoring breast cancer patients. The results of this study suggest that CSLEX may be more useful than CEA in combination with CA15-3 in monitoring breast cancer patients.
In our previous studies, we identified that exploratory eye movement (EEM) dysfunction appears to be specific to schizophrenia. The availability of a biological marker specific to schizophrenia would ...be useful for clinical diagnosis of schizophrenia. Consequently, we performed the discriminant analysis between schizophrenics and non-schizophrenics on a large sample using the EEM test data and examined an application of the EEM for clinical diagnosis of schizophrenia. EEM performances were recorded in 251 schizophrenics and 389 non-schizophrenics (111 patients with mood disorders, 28 patients with neurotic disorders and 250 normal controls). The patients were recruited from eight university hospitals and three affiliated hospitals. For this study with a large sample, we developed a new digital computerized version of the EEM test, which automatically handled large amounts of data. We measured four parameters: number of eye fixations (NEF), total eye scanning length (TESL), mean eye scanning length (MESL) and responsive search score (RSS). These parameters of schizophrenics differed significantly from those of the other three groups. The stepwise regression analysis selected the TESL and the RSS as the valid parameters for discriminating between schizophrenics and non-schizophrenics. In the discriminant analysis using the RSS and TESL as prediction parameters, 184 of the 251 clinically diagnosed schizophrenics were discriminated as having schizophrenia (sensitivity 73.3%); and 308 of the 389 clinically diagnosed non-schizophrenic subjects were discriminated as non-schizophrenics (specificity 79.2%). Based on our findings we believe that the EEM measures may be useful for the clinical diagnosis of schizophrenia.
Pressure dispersion is known as an important function for insoles. However it cannot be evaluated effectively with the conventional parameters. Therefore, we developed a new insole evaluation method ...based on pressure dispersion. We verified the pressure dispersion effects of the newly developed evaluation parameters. The subjects were healthy adults, 8 male and 3 female. Sample conditions were 5 types of different foam resin. We calculated three parameters based on foot pressure distribution during standing. The calculated parameters were conventional (Peak-pressure and Contact-area) and a new parameter (Pressure Dispersion Parameter; PDP). Each parameter was compared with the dispersion degree of sensory evaluation. The result of this study was that our new evaluation parameter (PDP) has a higher correlation with subjectivity than conventional parameters. It’s hoped that these results will establish sufficient evidence for the efficacy of our new insole.
This study aimed to determine whether velocity of downward(eccentric:ECC) phase affect jump height, mean and peak velocity,power, force, and rate of force development (RFD) of upward(concentric:CON) ...phase during jump squat (JSQ) with moderateload. Fifteen university rugby players were performed JSQconducted with ECC velocity of 2 seconds (ECC2s) and theirmaximum velocity (ECCMax) at 30% and 50% load of squatone repetition maximum (SQ1RM). JSQ with ECCMax showedsignificantly higher values of jumping height, mean and peakvelocity, power, force, and RFD, in comparison with JSQ withECC2s. These results suggest that during JSQ with a moderateload, performance of CON phase was revealed to be enhancedwith faster velocity of ECC phase.
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