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zadetkov: 235
1.
  • Merging old and new perspec... Merging old and new perspectives on nicotinic acetylcholine receptors
    Papke, Roger L. Biochemical pharmacology, 05/2014, Letnik: 89, Številka: 1
    Journal Article
    Recenzirano
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    This review covers history underlying the discovery of the molecular mediators of nicotine's effects in the brain and the diversity of the nicotinic acetylcholine receptor (nAChR) subtypes. Models ...
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2.
  • Functions and pharmacology ... Functions and pharmacology of α2β2 nicotinic acetylcholine receptors; in and out of the shadow of α4β2 nicotinic acetylcholine receptors
    Papke, Roger L. Biochemical pharmacology, 07/2024, Letnik: 225
    Journal Article
    Recenzirano

    Display omitted Although α2 was the first neuronal nicotinic acetylcholine receptor (nAChR) receptor subunit to be cloned, due to its low level of expression in rodent brain, its study has largely ...
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3.
  • Nicotinic acetylcholine rec... Nicotinic acetylcholine receptors: Conventional and unconventional ligands and signaling
    Papke, Roger L.; Lindstrom, Jon M. Neuropharmacology, 05/2020, Letnik: 168
    Journal Article
    Recenzirano
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    Postsynaptic nAChRs in the peripheral nervous system are critical for neuromuscular and autonomic neurotransmission. Pre- and peri-synaptic nAChRs in the brain modulate neurotransmission and are ...
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4.
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5.
  • Nicotinic Activity of Areco... Nicotinic Activity of Arecoline, the Psychoactive Element of "Betel Nuts", Suggests a Basis for Habitual Use and Anti-Inflammatory Activity
    Papke, Roger L; Horenstein, Nicole A; Stokes, Clare PloS one, 10/2015, Letnik: 10, Številka: 10
    Journal Article
    Recenzirano
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    Habitual chewing of "betel nut" preparations constitutes the fourth most common human self-administration of a psychoactive substance after alcohol, caffeine, and nicotine. The primary active ...
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6.
  • The many enigmas of nicotine
    Papke, Roger L Advances in pharmacology (1990), 2024, Letnik: 99
    Journal Article
    Recenzirano

    This review discusses the diverse effects of nicotine on the various nicotinic acetylcholine receptors of the central and peripheral nervous system and how those effects may promote the usage and ...
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7.
  • Looking below the surface o... Looking below the surface of nicotinic acetylcholine receptors
    Stokes, Clare; Treinin, Millet; Papke, Roger L Trends in pharmacological sciences, 08/2015, Letnik: 36, Številka: 8
    Journal Article
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    Highlights • Intracellular domains of Cys -loop receptors are variable and unique to each subunit. • Intracellular subdomains may contribute to ion-conducting submembrane portals. • The α7 ...
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8.
  • Therapeutic Targeting of α 7 Nicotinic Acetylcholine Receptors
    Papke, Roger L; Horenstein, Nicole A Pharmacological reviews, 07/2021, Letnik: 73, Številka: 3
    Journal Article
    Recenzirano

    The 7-type nicotinic acetylcholine receptor is one of the most unique and interesting of all the members of the cys-loop superfamily of ligand-gated ion channels. Since it was first identified ...
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9.
  • Positive allosteric modulat... Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations
    Williams, Dustin K.; Wang, Jingyi; Papke, Roger L. Biochemical pharmacology, 10/2011, Letnik: 82, Številka: 8
    Journal Article, Conference Proceeding
    Recenzirano
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    Neuronal nicotinic acetylcholine receptors (nAChR), recognized targets for drug development in cognitive and neuro-degenerative disorders, are allosteric proteins with dynamic interconversions ...
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10.
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zadetkov: 235

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