Background
Timeliness of care is an important dimension of health care quality. The determining factors of less timely care and their influence on the survival of patients with lung cancer (LC) ...remain uncertain.
Aims
To analyse the delays in the diagnosis and treatment of LC in our health area, the factors associated with the timeliness of care and their possible relationship with the survival of these patients.
Methods
A retrospective study was conducted on all patients with a cytohistologically confirmed diagnosis of LC between 1 June 2005 and 31 May 2008. The time delays for consultation (specialist delay), diagnosis (diagnosis delay), and treatment (treatment delay), were analysed, as well as the factors associated with these delays and the influence of the timeliness of care on survival.
Results
A total of 307 cases were included (87 % males). The mean specialist delay was 53.6 days (median 35 days), diagnosis delay 31.5 days (median 18 days), treatment delay 23.5 days (median 14 days). The greater age of the patient and a more advanced stage were associated with a shorter specialist delay. Male sex, a more advanced stage, and poor general status were associated with a shorter treatment delay. The survival is longer in patients with a longer treatment delay.
Conclusions
The delay in the diagnosis in our population seems to be excessively long. The greater the age, a more advanced tumour stage, male sex, and poor general health status are associated with shorter delays. A longer treatment delay is associated with a longer survival.
First measurement of the Λc+→ pη′ decay Li, S. X.; Shen, C. P.; Adachi, I. ...
The journal of high energy physics,
03/2022, Letnik:
2022, Številka:
3
Journal Article
Recenzirano
Odprti dostop
A
bstract
We present the first measurement of the branching fraction of the singly Cabibbo-suppressed (SCS) decay
Λ
c
+
→ pη
′ with
η
′
→ ηπ
+
π
−
, using a data sample corresponding to an integrated ...luminosity of 981 fb
−
1
, collected by the Belle detector at the KEKB
e
+
e
−
asymmetric-energy collider. A significant
Λ
c
+
→ pη
′ signal is observed for the first time with a signal significance of 5.4
σ
. The relative branching fraction with respect to the normalization mode
Λ
c
+
→ pK
−
π
+
is measured to be
B
Λ
c
+
→
pη
′
B
Λ
c
+
→
pK
−
π
+
=
7.54
±
1.32
±
0.73
×
10
−
3
,
where the uncertainties are statistical and systematic, respectively. Using the world-average value of
B
Λ
c
+
→
pK
−
π
+
= (6
.
28
±
0
.
32)
×
10
−
2
, we obtain
B
Λ
c
+
→
pη
′
=
4.73
±
0.82
±
0.46
±
0.24
×
10
−
4
,
where the uncertainties are statistical, systematic, and from
B
Λ
c
+
→
pK
−
π
+
, respectively.
We studied the impact of 13-valent pneumococcal conjugate vaccine (PCV13) on the incidence of invasive pneumococcal disease (IPD) and serotype distribution in a region with intermediate levels of ...vaccination (around 64% in children aged <2 years).
Surveillance data on IPD cases reported by microbiologists participating in the Microbiological Reporting System of Catalonia during 2006–2014 were analysed. We compared estimated incidence rate (IR) ratios for serotypes included in PCV7, PCV10non7, PCV13non10 and non-PCV13 between the PCV7 (2006–2009) and PCV13 periods (2010–2014). IR were corrected for missing serotypes according to year and age groups: <2 years, 2–4 years, 5–64 years and ≥65 years.
A total of 9338 IPD cases were reported. Overall IPD incidence declined by 26.2% (from 16.4 to 12.1) in the PCV13 period. The largest decrease was observed in children aged 2–4 years (44.5%, from 37.4 to 20.8). Pneumonia fell in all age groups with the largest reduction in children aged 2–4 years (49.3%) and <2 years (42%). PCV13 serotypes decreased significantly in all age groups, from 52% (31.6 to 15.1) in children aged 2–4 years to 35% (22.8 to 14.8) in adults aged ≥65 years. Non-PCV13 serotypes rose by 13% (14.8 to 16.8) in people aged ≥65 years.
In a region with intermediate vaccination coverage, the introduction of PCV13 has reduced the overall incidence of IPD, mainly due to the decrease in PCV13 serotypes in all age groups, suggesting herd immunity. Non-PCV13 serotypes have increased in adults aged ≥65 years, suggesting serotype replacement. Higher PCV13 vaccination coverage in children will further reduce IPD incidence in all age groups.
A
bstract
We report the first measurement of the inclusive
e
+
e
−
→
$$ b\overline{b} $$
b
b
¯
→
$$ {D}_s^{\pm } $$
D
s
±
X
and
e
+
e
−
→
$$ b\overline{b} $$
b
b
¯
→ D
0
/
$$ {\overline{D}}^0 $$
D
¯
...0
X
cross sections in the energy range from 10
.
63 to 11
.
02 GeV. Based on these results, we determine
σ
(
e
+
e
−
→
$$ {B}_s^0{\overline{B}}_s^0 $$
B
s
0
B
¯
s
0
X
) and
σ
(
e
+
e
−
→
$$ B\overline{B} $$
B
B
¯
X
) in the same energy range. We measure the fraction of
$$ {B}_s^0 $$
B
s
0
events at Υ(10860) to be
f
s
= (
$$ {22.0}_{-2.1}^{+2.0} $$
22.0
−
2.1
+
2.0
)%. We determine also the ratio of the
$$ {B}_s^0 $$
B
s
0
inclusive branching fractions
$$ \mathcal{B} $$
B
(
$$ {B}_s^0 $$
B
s
0
→ D
0
/
$$ {\overline{D}}^0 $$
D
¯
0
X
)
/
$$ \mathcal{B} $$
B
(
$$ {B}_s^0 $$
B
s
0
→
$$ {D}_s^{\pm } $$
D
s
±
X
) = 0
.
416 ± 0
.
018 ± 0
.
092. The results are obtained using the data collected with the Belle detector at the KEKB asymmetric-energy
e
+
e
−
collider.
A
bstract
We present a search for the lepton-flavor-violating decays
B
s
0
→
ℓ
∓
τ
±
, where
ℓ
=
e, μ
, using the full data sample of 121 fb
−
1
collected at the Υ(5
S
) resonance with the Belle ...detector at the KEKB asymmetric-energy
e
+
e
−
collider. We use
B
s
0
B
¯
s
0
events in which one
B
s
0
meson is reconstructed in a semileptonic decay mode and the other in the signal mode. We find no evidence for
B
s
0
→ ℓ
∓
τ
±
decays and set upper limits on their branching fractions at 90% confidence level as
B
(
B
s
0
→ e
∓
τ
±
)
<
14
×
10
−
4
and
B
(
B
s
0
→ μ
∓
τ
±
)
<
7
.
3
×
10
−
4
. Our result represents the first upper limit on the
B
s
0
→ e
∓
τ
±
decay rate.
A
bstract
Using a data sample of 980 fb
−
1
collected with the Belle detector at the KEKB asymmetric-energy
e
+
e
−
collider, we study for the first time the singly Cabibbo-suppressed decays
$$ ...{\Omega}_c^0\to {\Xi}^{-}{\pi}^{+} $$
Ω
c
0
→
Ξ
−
π
+
and Ω
−
K
+
and the doubly Cabibbo-suppressed decay
$$ {\Omega}_c^0\to {\Xi}^{-}{K}^{+} $$
Ω
c
0
→
Ξ
−
K
+
. Evidence for an
$$ {\Omega}_c^0 $$
Ω
c
0
signal in the
$$ {\Omega}_c^0 $$
Ω
c
0
→
Ξ
−
π
+
mode is reported with a significance of 4
.
5
σ
including systematic uncertainties. The ratio of branching fractions to the normalization mode
$$ {\Omega}_c^0 $$
Ω
c
0
→
Ω
−
π
+
is measured to be
$$ \mathcal{B}\left({\Omega}_c^0\to {\Xi}^{-}{\pi}^{+}\right)/\mathcal{B}\left({\Omega}_c^0\to {\Omega}^{-}{\pi}^{+}\right)=0.253\pm 0.052\left(\textrm{stat}.\right)\pm 0.030\left(\textrm{syst}.\right). $$
B
Ω
c
0
→
Ξ
−
π
+
/
B
Ω
c
0
→
Ω
−
π
+
=
0.253
±
0.052
stat
.
±
0.030
syst
.
.
No significant signals of
$$ {\Omega}_c^0\to {\Xi}^{-}{K}^{+} $$
Ω
c
0
→
Ξ
−
K
+
and Ω
−
K
+
modes are found. The upper limits at 90% confidence level on ratios of branching fractions are determined to be
$$ \mathcal{B}\left({\Omega}_c^0\to {\Xi}^{-}{K}^{+}\right)/\mathcal{B}\left({\Omega}_c^0\to {\Omega}^{-}{\pi}^{+}\right)<0.070 $$
B
Ω
c
0
→
Ξ
−
K
+
/
B
Ω
c
0
→
Ω
−
π
+
<
0.070
and
$$ \mathcal{B}\left({\Omega}_c^0\to {\Omega}^{-}{K}^{+}\right)/\mathcal{B}\left({\Omega}_c^0\to {\Omega}^{-}{\pi}^{+}\right)<0.29. $$
B
Ω
c
0
→
Ω
−
K
+
/
B
Ω
c
0
→
Ω
−
π
+
<
0.29
.
Charged lepton flavor violation is forbidden in the Standard Model but possible in several new physics scenarios. In many of these models, the radiative decays τ± → ℓ±γ (ℓ = e, μ) are predicted to ...have a sizeable probability, making them particularly interesting channels to search at various experiments. An updated search via τ± → ℓ±γ using full data of the Belle experiment, corresponding to an integrated luminosity of 988 fb–1, is reported for charged lepton flavor violation. No significant excess over background predictions from the Standard Model is observed, and the upper limits on the branching fractions, B(τ± → μ±γ) ≤ 4.2 × 10–8 and B(τ± → e±γ) ≤ 5.6 × 10–8, are set at 90% confidence level.
We report the first measurement of the exclusive cross sections e+e- → $B\overline{B}$, e+e- → $B{\overline{B}}^{\ast }$, and e+e- → ${B}^{\ast }{\overline{B}}^{\ast }$ in the energy range from 10.63 ...GeV to 11.02 GeV. The B mesons are fully reconstructed in a large number of hadronic final states and the three channels are identified using a beam-constrained-mass variable. The shapes of the exclusive cross sections show oscillatory behavior with several maxima and minima. The results are obtained using data collected by the Belle experiment at the KEKB asymmetric-energy e+e- collider.
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