STEADY STREAMING Riley, N
Annual review of fluid mechanics,
01/2001, Letnik:
33, Številka:
1
Journal Article
Recenzirano
The time-average of a fluctuating flow often results in a nonzero mean. Such
steady streaming may result directly from the action of an oscillatory
nonconservative body force or, if such a force is ...conservative, indirectly
through the action of Reynolds stresses in the main body of the fluid or in
thin boundary layers at no-slip boundaries. A theory for such streaming flows
is developed for homogeneous fluids. For flows with a free surface it is
demonstrated that a mechanism for steady streaming exists even in an inviscid
fluid. Diverse areas in which steady streaming flows may be important are
discussed.
The Developing Inclusive Youth program is a classroom‐based, individually administered video tool that depicts peer‐based social and racial exclusion, combined with teacher‐led discussions. A ...multisite randomized control trial was implemented with 983 participants (502 females; 58.5% White, 41.5% Ethnic/racial minority; Mage = 9.64 years) in 48 third‐, fourth‐, and fifth‐grade classrooms across six schools. Children in the program were more likely to view interracial and same‐race peer exclusion as wrong, associate positive traits with peers of different racial, ethnic, and gender backgrounds, and report play with peers from diverse backgrounds than were children in the control group. Many approaches are necessary to achieve antiracism in schools. This intervention is one component of this goal for developmental science.
Organic dyes that absorb and emit in the near-infrared (NIR) region are potentially noninvasive, high-resolution, and rapid biological imaging materials. Indolizine donor-based cyanine and squaraine ...dyes with water-solubilizing sulfonate groups were targeted in this study due to strong absorptions and emissions in the NIR region. As previously observed for nonwater-soluble derivatives, the indolizine group with water-solubilizing groups retains a substantial shift toward longer wavelengths for both absorption and emission with squaraines and cyanines relative to classically researched indoline donor analogues. Very high quantum yields (as much as 58%) have been observed with absorption and emission >700 nm in fetal bovine serum. Photostability studies, cell culture cytotoxicity, and cell uptake specificity profiles were all studied for these dyes, demonstrating exceptional biological imaging suitability.
The General Factor of Psychopathology Smith, Gregory T; Atkinson, Emily A; Davis, Heather A ...
Annual review of clinical psychology,
05/2020, Letnik:
16, Številka:
1
Journal Article
Recenzirano
Odprti dostop
An important advance in understanding and defining mental disorders has been the development of empirical approaches to mapping dimensions of dysfunction and their interrelatedness. Such empirical ...approaches have consistently observed intercorrelations among the many forms of psychopathology, leading to the identification of a general factor of psychopathology (the p factor). In this article, we review empirical support for p, including evidence for the stability and criterion validity of p. Further, we discuss the strong relationship between p and both the general factor of personality and the general factor of personality disorder, substantive interpretations of p, and the potential clinical utility of p. We posit that proposed substantive interpretations of p do not explain the full range of symptomatology typically included in p. The most plausible explanation is that p represents an index of impairment that has the potential to inform the duration and intensity of a client's mental health treatment.
Alzheimer's disease (AD) is defined by the presence of intraneuronal neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau aggregates as well as extracellular amyloid-beta plaques. The ...presence and spread of tau pathology through the brain is classified by Braak stages and thought to correlate with the progression of AD. Several
and
studies have examined the ability of tau pathology to move from one neuron to the next, suggesting a "prion-like" spread of tau aggregates may be an underlying cause of Braak tau staging in AD. Using the HEK293 Tau
-P301S-CFP/YFP expressing biosensor cells as a highly sensitive and specific tool to identify the presence of seed competent aggregated tau in brain lysate-i.e., tau aggregates that are capable of recruiting and misfolding monomeric tau-, we detected substantial tau seeding levels in the entorhinal cortex from human cases with only very rare NFTs, suggesting that soluble tau aggregates can exist prior to the development of overt tau pathology. We next looked at tau seeding levels in human brains of varying Braak stages along six regions of the Braak Tau Pathway. Tau seeding levels were detected not only in the brain regions impacted by pathology, but also in the subsequent non-pathology containing region along the Braak pathway. These data imply that pathogenic tau aggregates precede overt tau pathology in a manner that is consistent with transneuronal spread of tau aggregates. We then detected tau seeding in frontal white matter tracts and the optic nerve, two brain regions comprised of axons that contain little to no neuronal cell bodies, implying that tau aggregates can indeed traverse along axons. Finally, we isolated cytosolic and synaptosome fractions along the Braak Tau Pathway from brains of varying Braak stages. Phosphorylated and seed competent tau was significantly enriched in the synaptic fraction of brain regions that did not have extensive cellular tau pathology, further suggesting that aggregated tau seeds move through the human brain along synaptically connected neurons. Together, these data provide further evidence that the spread of tau aggregates through the human brain along synaptically connected networks results in the pathogenesis of human Alzheimer's disease.
Hyperspectral imaging systems (HSIs) are becoming widespread in the mining industry for mineral classification. The spectral features detectable from near infrared to long-wave infrared make HSIs a ...potentially efficient tool for exploration, clay mapping, and leach pad modeling. However, the redundancy of hyperspectral data makes the analysis of hyperspectral images complicated and slow. Many researchers have proposed different algorithms and strategies to speed up processing and increase accuracy. These procedures rely on endmember extraction as one of the critical steps. However, no one has tested whether endmember extraction actually improves accuracy under all circumstances. Eliminating endmember extraction, if possible, would speed up the analysis of hyperspectral data. This study tested whether endmember extraction improves the accuracy and efficiency of mapping materials at leach pads, which are among the most complicated situations in mining environments. We compared the accuracy of abundance maps produced with fully constrained least squares (FCLS) (a) with endmember extraction by N-FINDR and (b) without endmember extraction, using a spectral library instead. The results from endmember extraction showed lower accuracy than the results from using a spectral library, probably because the spectral data were noisy and the scanned materials were mixtures. The application of FCLS to hyperspectral images provides useful information for metallurgists. The abundance maps showed that kaolinite, muscovite, and precipitation (hexahydrite and pickeringite) were the dominant minerals on the leach pad. The abundance maps of pipes and precipitation can be used to monitor leaching conditions. Lixiviant ponds mapped out in the abundance map of water can indicate saturation. This technique can also detect organic leakage and agglomeration effectiveness, but it will need different wavelength ranges and more future study. This paper also suggests best practices for using hyperspectral imaging systems to map leach pads.
In the field of writing center research there is a paucity of information regarding tutoring students with dyslexia. This comes as no surprise considering it is only in the last 50 years that there ...has been a conscious effort to include those who have exceptionalities in all areas of education. In addition to a lack of research and training there is another issue that arises with disclosing exceptionalities. Those studying dyslexia have found that students are hesitant to disclose their learning disability because of the stigma and feelings of differentiation from their peers (Brizee et al., 2012). The question then becomes how we prepare tutors so they may approach a diverse group of learners and feel they have the skills to work with any student without disclosing their disability. Part of implementing the Universal Design for Learning approach is preparing tutors to accommodate a range of learning disabilities, exceptionalities, and cultures. It is important for tutors to understand common characteristics of dyslexic writers and strategies for working with them. Effective strategies include repeating explicit instruction, emphasizing phonetics, and mind mapping/chunking information. This project is focused on helping secondary writing center tutors and faculty to feel they have enough knowledge about dyslexia to help students who choose not to disclose their disability and offer strategies that they may utilize when working with dyslexic students. Furthermore, this project affirms the importance of creating an equitable learning environment for all students who seek the support of a writing center.
To evaluate the prevalence and risk factors of wrist pain.
Systematic review.
The MEDLINE and EMBASE via OVID, CINAHL and SPORTDiscus via EBSCO databases were searched from database inception to 9th ...March 2018. Specific criteria were used to define inclusion and exclusion. Data was extracted independently by a pair of reviewers.
In total 32 cross sectional studies were identified for inclusion (1 with a longitudinal component). The median prevalence of wrist pain in the general population and non-manual workers within the short term (within last week) was 6 and 4.2% within the medium term (> 1 week and within a year). The median prevalence of wrist pain in physically demanding occupations and sports people was 10% within the short term and 24% within the medium term. Non-modifiable factors associated with wrist pain included increased age (1 study in adults and 3 studies in children/adolescents) and female sex (2 studies). Modifiable risk factors included high job physical strain (2 studies), high job psychological strain (1 study), abnormal physeal morphology in children/adolescents (2 studies), high frequency impact tool use (1 study) and effort reward imbalance (1 study).
Wrist pain is highly prevalent in groups who partake in physically demanding activities from day to day such as manual labourers and sportspeople. It is less prevalent in the general population and non-manual workers, although there is a relative lack of research in the general population.
The review protocol was registered with PROSPERO under the registration number CRD42018090834.
1 (Prognostic study).
Hockey is a complex and multifaceted game, yet many of the statistical tools used to evaluate performance are univariate. To garner a better understanding of hockey's multifaceted nature, two ...structural equation models (SEMs) assessing the interrelations between offense, defense, and possession were built from three seasons of NHL data. Overall, it was found that the concepts of offense, defense, and possession are best understood via a small constellation of measured variables, and that offense mediates the relationship between possession and defense such that higher levels of offense leads to poorer defensive performance. These findings are discussed within the context of ranking player performance.
In response to some resource inequalities, children give priority to moral concerns. Yet, in others, children show ingroup preferences in their evaluations and resource allocations. The present study ...built upon this knowledge by investigating children's and young adults’ (N = 144; 5–6‐year‐olds, Mage = 5.83, SDage = .97; 9–11‐year‐olds, Mage = 10.74, SDage = .68; and young adults, Mage = 19.92, SDage = 1.10) evaluations and allocation decisions in a science inequality context. Participants viewed vignettes in which male and female groups received unequal amounts of science supplies, then evaluated the acceptability of the resource inequalities, allocated new boxes of science supplies between the groups, and provided justifications for their choices. Results revealed both children and young adults evaluated inequalities of science resources less negatively when girls were disadvantaged than when boys were disadvantaged. Further, 5‐ to 6‐year‐old participants and male participants rectified science resource inequalities to a greater extent when the inequality disadvantaged boys compared to when it disadvantaged girls. Generally, participants who used moral reasoning to justify their responses negatively evaluated and rectified the resource inequalities, whereas participants who used group‐focused reasoning positively evaluated and perpetuated the inequalities, though some age and participant gender findings emerged. Together, these findings reveal subtle gender biases that may contribute to perpetuating gender‐based science inequalities both in childhood and adulthood.
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