Metoda citatne analize jedna je od nenametljivih načina vrednovanja knjižničnog fonda. To je kvantitativna metoda kojom se proučavaju popisi literature u znanstvenim i stručnim radovima na odabranom ...uzorku publikacija koja odgovara svrsi i cilju knjižnice. Cilj ovog istraživanja bio je steći uvid u korištenje knjižničnog fonda kao cjeline metodom citatne analize doktorskih disertacija. Za provedeno istraživanje odabran je uzorak doktorskih disertacija koje su obranjene na Sveučilištu u Zagrebu. Pri odabiru disertacija korišteni su sljedeći kriteriji: znanstvenici (autori) su korisnici Nacionalne i sveučilišne knjižnice u Zagrebu i disertacije su obranjene na zagrebač- kom sveučilištu u 2013. godini. Ovim se istraživanjem nastojalo utvrditi u kojoj mjeri korisnici koriste fond Nacionalne i sveučilišne knjižnice u Zagrebu u svom znanstve- nom radu.
Pojava časopisa i izdavača upitne kvalitete postala je velik problem za znanstvenu
komunikaciju, ali i za razvoj znanosti i ljudskoga društva. Takvi se
časopisi objavljuju u otvorenom pristupu, ...koriste poslovni model naplate troškova
objave autorima, a pri tome ne provode recenziju, već objavljuju sve bez
ikakvih kriterija. Prema tome, osnovno obilježje časopisa upitne kvalitete jest
neselektivnost u procesu odabira rukopisa zbog nepostojanja recenzijskog
postupka. Od izuzetne je važnosti da takve časopise korisnici (znanstvenici,
ali i šira javnost) znaju prepoznati. Cilj je rada istražiti pojavu časopisa i izdavača
upitne kvalitete kao anomaliju unutar izgrađivanoga modela znanstvene
komunikacije putem znanstvenih časopisa u hrvatskoj znanstvenoj zajednici.
A 96m long sediment core (S10-33) from the Mali Ston Channel (Adriatic Sea) showed large natural variation in carbonate share (between 1% and 95%) and concentration of elements. These variations ...indicate rather significant changes in fine-grained sediment that was deposited in this area during Younger Pleistocene and Holocene. Unaffected by anthropogenic influence, sediment in the core was used to determine background concentration of trace elements in sediment with various carbonate content. Here we propose a method of the normalization of trace elements to carbonate share, in order to assess natural/background concentration of metals in sediments consisting of carbonates and alumosilicates in various proportions. Six characteristic metals (Co, Cr, Cu, Ni, Pb, and Zn) that were normalized to carbonate share showed very good correlation, with much higher background concentrations in alumosilicate than in carbonate end member. Simple formulas were proposed to easily determine background concentration of these elements, in coastal and shelf depositional environments with mixed carbonate-alumosilicate sediments.
•Estimation of natural/background concentrations of elements in sediments•Mixed carbonate-alumosilicate sediments•Large variation in carbonate content and concentration of trace metals along core•Normalization of trace element concentration to carbonate share•Simple method to determine background concentrations of trace elements in sediment
The role of trace elements in the pathogenesis of liver cirrhosis and its complications is still not clearly understood. Serum concentrations of zinc, copper, manganese and magnesium were determined ...in 105 patients with alcoholic liver cirrhosis and 50 healthy subjects by means of plasma sequential spectrophotometer. Serum concentrations of zinc were significantly lower (median 0.82 vs. 11.22 micromol/L, p < 0.001) in patients with liver cirrhosis in comparison to controls. Serum concentrations of copper were significantly higher in patients with liver cirrhosis (median 21.56 vs. 13.09 micromol/L, p < 0.001) as well as manganese (2.50 vs. 0.02 micromol/L, p < 0.001). The concentration of magnesium was not significantly different between patients with liver cirrhosis and controls (0.94 vs. 0.88 mmol/L, p = 0.132). There were no differences in the concentrations of zinc, copper, manganese and magnesium between male and female patients with liver cirrhosis. Only manganese concentration was significantly different between Child-Pugh groups (p = 0.036). Zinc concentration was significantly lower in patients with hepatic encephalopathy in comparison to cirrhotic patients without encephalopathy (0.54 vs. 0.96 micromol/L, p = 0.002). The correction of trace elements concentrations might have a beneficial effect on complications and maybe progression of liver cirrhosis. It would be recommendable to provide analysis of trace elements as a routine.
Background/Objectives: Acute necrotizing pancreatitis (ANP) with secondary infection of necrotic tissue is associated with a high rate of complications and mortality. The optimal approach is still ...debatable, but the minimally invasive modality has gained great attention in the last decade as it follows the principle of applying minimal surgical trauma to achieve a satisfying therapeutic objective. We compared clinical outcomes between the step-up approach (SUA) and open necrosectomy (ON) in the treatment of acute necrotizing pancreatitis. Methods: A prospective cohort study over the period of 2011–2021 in a university teaching hospital was performed. Results of 99 consecutive patients with ANP who required surgical/radiological intervention were collected. A case match analysis (2:1) was performed, and the final groups comprised 40 patients in the OA group and 20 patients in the SUA group. Demographic, clinicopathologic, and treatment data were reviewed. Results: Baseline characteristics and disease severity were comparable between the two groups. The patients from the SUA group had a significantly lower morbidity rate and rate of pancreatic insufficiency. Death occurred in 4 of 20 patients (20%) in the SUA group and in 11 of 40 patients (27.5%) in the ON group (risk ratio with the step-up approach, 0.72; 95% confidence interval, 0.26 to 1.99; p = 0.53). Conclusions: A minimally invasive step-up approach provides comparable outcomes to open necrosectomy in the treatment of ANP with infected pancreatic necrosis. While mortality and hospital stay were comparable between the groups, morbidity and pancreatic insufficiency were significantly lower in the SUA group. Further studies on a larger number of patients are required to define the place of SUA in the modern treatment of ANP.
Ruptured hepatocellular carcinoma (HCC) is a well-known serious complication of this most common primary liver malignancy. However, when HCC rupture is associated with other focal liver lesions, the ...diagnosis and therapy may be very challenging. Correct differentiation of focal liver lesions is of paramount importance for successful treatment. The aim of this report is to present a unique case of HCC rupture complicated with liver abscess, hematoma and portal vein thrombosis. We discuss possible pathophysiological mechanisms and radiologic findings of such clinical scenarios and review literature related to the management of HCC rupture.
Akutna bubrežna ozljeda je česta u prijevremeno rođene novorođenčadi. Zbog funkcijske i razvojne nezrelosti bubrega oni su osjetljiviji
na bubrežnu ozljedu u odnosu na stariju dojenčad i djecu. Ne ...postoji jedinstvena defi nicija za akutnu bubrežnu ozljedu u novorođenčadi.
Etiologija bubrežne ozljede je često multifaktorska i može nastati kao posljedica prenatalnih, perinatalnih i postnatalnih
zbivanja. Koncentracija serumskog kreatinina novorođenčeta u trenutku porođaja podjednaka je majčinoj. Prikazujemo slučaj
prijevremeno rođenih blizanki koje su primljene u Jedinicu intenzivnog liječenja zbog akutne bubrežne ozljede. Rezultati laboratorijskih
analiza su pokazali podjednako povišene vrijednosti ureje i serumskog kreatinina obiju blizanki, praćene metaboličkom alkalozom.
Povišene vrijednosti ureje i serumskog kreatinina bile su posljedica majčine neprepoznate bubrežne bolesti. Sedmog postnatalnog
dana vrijednosti kreatinina i ureje su se normalizirale. U svim slučajevima povišenih vrijednosti serumskog kreatinina u prva 72
sata života nužno je evaluirati majčinu bubrežnu funkciju.
The role of trace elements in the pathogenesis of liver cirrhosis and its complications is still not clearly understood.
Serum concentrations of zinc, copper, manganese and magnesium were determined ...in 105 patients with alcoholic liver
cirrhosis and 50 healthy subjects by means of plasma sequential spectrophotometer. Serum concentrations of zinc were
significantly lower (median 0.82 vs. 11.22 mol/L, p<0.001) in patients with liver cirrhosis in comparison to controls.
Serum concentrations of copper were significantly higher in patients with liver cirrhosis (median 21.56 vs. 13.09 mol/L,
p<0.001) as well as manganese (2.50 vs. 0.02 mol/L, p<0.001). The concentration of magnesium was not significantly
different between patients with liver cirrhosis and controls (0.94 vs. 0.88 mmol/L, p=0.132). There were no differences in
the concentrations of zinc, copper, manganese and magnesium between male and female patients with liver cirrhosis.
Only manganese concentration was significantly different between Child-Pugh groups (p=0.036). Zinc concentration
was significantly lower in patients with hepatic encephalopathy in comparison to cirrhotic patients without encephalopathy
(0.54 vs. 0.96 mol/L, p=0.002). The correction of trace elements concentrations might have a beneficial effect on
complications and maybe progression of liver cirrhosis. It would be recommendable to provide analysis of trace elements
as a routine.
