We report on the results of optical, near-infrared (NIR), and mid-infrared observations of the black hole X-ray binary candidate (BHB) MAXI J1535-571 during its 2017/2018 outburst. During the first ...part of the outburst (MJD 58004-58012), the source shows an optical-NIR spectrum that is consistent with an optically thin synchrotron power law from a jet. After MJD 58015, however, the source faded considerably, the drop in flux being much more evident at lower frequencies. Before the fading, we measure a dereddened flux density of 100 mJy in the mid-infrared, making MAXI J1535-571 one of the brightest mid-infrared BHBs known so far. A significant softening of the X-ray spectrum is evident contemporaneous with the infrared fade. We interpret it as being due to the suppression of the jet emission, similar to the accretion-ejection coupling seen in other BHBs. However, MAXI J1535-571 did not transition smoothly to the soft state, instead showing X-ray hardness deviations associated with infrared flaring. We also present the first mid-IR variability study of a BHB on minute timescales, with a fractional rms variability of the light curves of ∼15%-22%, which is similar to that expected from the internal shock jet model, and much higher than the optical fractional rms ( 7%). These results represent an excellent case of multiwavelength jet spectral timing and demonstrate how rich, multiwavelength time-resolved data of X-ray binaries over accretion state transitions can help in refining models of the disk-jet connection and jet launching in these systems.
A better understanding of prognostic factors in ulcerative colitis (UC) could improve patient management and reduce complications. We aimed to identify evidence-based predictors for outcomes in ...pediatric UC, which may be used to optimize treatment algorithms.
Potential outcomes worthy of prediction in UC were determined by surveying 202 experts in pediatric UC. A systematic review of the literature, with selected meta-analysis, was performed to identify studies that investigated predictors for these outcomes. Multiple national and international meetings were held to reach consensus on evidence-based statements.
Consensus was reached on 31 statements regarding predictors of colectomy, acute severe colitis (ASC), chronically active pediatric UC, cancer and mortality. At diagnosis, disease extent (6 studies, N = 627; P = .035), Pediatric Ulcerative Colitis Activity Index score (4 studies, n = 318; P < .001), hemoglobin, hematocrit, and albumin may predict colectomy. In addition, family history of UC (2 studies, n = 557; P = .0004), extraintestinal manifestations (4 studies, n = 526; P = .048), and disease extension over time may predict colectomy, whereas primary sclerosing cholangitis (PSC) may be protective. Acute severe colitis may be predicted by disease severity at onset and hypoalbuminemia. Higher Pediatric Ulcerative Colitis Activity Index score and C-reactive protein on days 3 and 5 of hospital admission predict failure of intravenous steroids. Risk factors for malignancy included concomitant diagnosis of primary sclerosing cholangitis, longstanding colitis (>10 years), male sex, and younger age at diagnosis.
These evidence-based consensus statements offer predictions to be considered for a personalized medicine approach in treating pediatric UC.
In this work, a method for the rapid synthesis of metallic microtracks on polyetherimide is presented. The method relies on the photosynthesis of silver nanoparticles on the surface of the polymer ...substrates from photosensitive silver chloride (AgCl), which is synthesized directly on the polyetherimide surface. The study reveals that the use of AgCl as a photosensitive intermediate accelerates the reactions leading to the formation of silver nanoparticles by up to two orders of magnitude faster than other photodecomposition schemes. The patterning can be conducted under blue light, with notable advantages over UV exposure. Polymers of significant interest to the microelectronics and 3D printing industries can be directly patterned by light using this photography‐inspired technique at throughputs high enough to be commercially advantageous. Light exposures as short as a few seconds are sufficient to allow the direct metallization of the illuminated polyetherimide surface. The results show that the silver required for the seed layer is minimal, and the later copper electroless plating results in the selective growth of conductive tracks for circuitry on the light‐patterned areas, both on flexible films and 3D printed surfaces.
A rapid photopatterning method for the selective plating on polyetherimide is presented. The use of AgCl as photosensitive intermediate allows manufacturing with very short exposures. Conductive copper tracks are produced on both flexible substrates for microelectronics and 3D printed pieces.
ABSTRACT
Radio continuum observations offer a new window on compact objects in globular clusters compared to typical X-ray or optical studies. As part of the MAVERIC survey, we have used the ...Australia Telescope Compact Array to carry out a deep (median central noise level ≈4 $\mu$Jy beam-1) radio continuum survey of 26 southern globular clusters at central frequencies of 5.5 and 9.0 GHz. This paper presents a catalogue of 1285 radio continuum sources in the fields of these 26 clusters. Considering the surface density of background sources, we find significant evidence for a population of radio sources in seven of the 26 clusters, and also identify at least 11 previously known compact objects (six pulsars and five X-ray binaries). While the overall density of radio continuum sources with 7.25-GHz flux densities ≳ 20 $\mu$Jy in typical globular clusters is relatively low, the survey has already led to the discovery of several exciting compact binaries, including a candidate ultracompact black hole X-ray binary in 47 Tuc. Many of the unclassified radio sources near the centres of the clusters are likely to be true cluster sources, and multiwavelength follow-up will be necessary to classify these objects and better understand the demographics of accreting compact binaries in globular clusters.
Abstract
We present a detailed study of the evolution of the Galactic black hole transient GRS 1716−249 during its 2016–2017 outburst at optical (Las Cumbres Observatory), mid-infrared (Very Large ...Telescope), near-infrared (Rapid Eye Mount telescope), and ultraviolet (the Neil Gehrels Swift Observatory Ultraviolet/Optical Telescope) wavelengths, along with archival radio and X-ray data. We show that the optical/near-infrared and UV emission of the source mainly originates from a multi-temperature accretion disk, while the mid-infrared and radio emission are dominated by synchrotron emission from a compact jet. The optical/UV flux density is correlated with the X-ray emission when the source is in the hard state, consistent with an X-ray irradiated accretion disk with an additional contribution from the viscous disk during the outburst fade. We find evidence for a weak, but highly variable jet component at mid-infrared wavelengths. We also report the long-term optical light curve of the source and find that the quiescent
i
′
-band magnitude is 21.39 ± 0.15 mag. Furthermore, we discuss how previous estimates of the system parameters of the source are based on various incorrect assumptions, and so are likely to be inaccurate. By comparing our GRS 1716−249 data set to those of other outbursting black hole X-ray binaries, we find that while GRS 1716−249 shows similar X-ray behavior, it is noticeably optically fainter, if the literature distance of 2.4 kpc is adopted. Using several lines of reasoning, we argue that the source distance is further than previously assumed in the literature, likely within 4–17 kpc, with a most likely range of ∼4–8 kpc.
A New Microquasar Candidate in M83 Soria, Roberto; Blair, William P.; Long, Knox S. ...
The Astrophysical journal,
01/2020, Letnik:
888, Številka:
2
Journal Article
Recenzirano
Odprti dostop
Microquasars are neutron star or black hole X-ray binaries with jets. These jets can create bubbles of hot plasma shock ionized that can masquerade as peculiar supernova remnants (SNRs) in ...extragalactic surveys. To see if this is the case in the well-studied spiral galaxy M83, where one microquasar candidate (M83-MQ1) has already been identified, we studied the properties of nine SNR candidates, selected because of their elongated or irregular morphology, from the set of previously identified SNRs in that galaxy. Using multiwavelength data from Chandra, the Hubble Space Telescope, Gemini, and the Australia Telescope Compact Array, we found that at least six of our nine sources are best interpreted as SNRs. For one source, we do not have enough observational data to explain its linear morphology. Another source shows a nebular optical spectrum dominated by photoionization by O stars, but its excess Fe ii and radio luminosity suggest a possible hidden SNR. Finally, one source (S2) shows an elongated structure of ionized gas, two radio sources along that line, and an accretion-powered X-ray source in between them (the Chandra source L14-139). While S2 could be a chance alignment of multiple SNRs and one X-ray binary, it seems more likely that it is a single physical structure powered by the jet from the accreting compact object. In the latter case, the size and luminosity of S2 suggest a kinetic power of ∼1040 erg s−1, in the same class as the most powerful microquasars in the local universe (e.g., S26 in NGC 7793 and SS 433 in our own Galaxy).
We report on a multi-wavelength study of the unclassified X-ray source CXOU J110926.4−650224 (J1109). We identified the optical counterpart as a blue star with a magnitude of ∼20.1 (3300–10500 Å). ...The optical emission was variable on timescales from hundreds to thousands of seconds. The spectrum showed prominent emission lines with variable profiles at different epochs. Simultaneous XMM-Newton and NuSTAR observations revealed a bimodal distribution of the X-ray count rates on timescales as short as tens of seconds, as well as sporadic flaring activity. The average broad-band (0.3–79 keV) spectrum was adequately described by an absorbed power law model with photon index of Γ = 1.63 ± 0.01 (at 1σ c.l.), and the X-ray luminosity was (2.16 ± 0.04) × 1034 erg s−1 for a distance of 4 kpc. Based on observations with different instruments, the X-ray luminosity has remained relatively steady over the past ∼15 years. J1109 is spatially associated with the gamma-ray source FL8Y J1109.8−6500, which was detected with Fermi at an average luminosity of (1.5 ± 0.2) × 1034 erg s−1 (assuming the distance of J1109) over the 0.1–300 GeV energy band between 2008 and 2016. The source was undetected during ATCA radio observations that were simultaneous with NuSTAR, down to a 3σ flux upper limit of 18 μJy beam−1 (at 7.25 GHz). We show that the phenomenological properties of J1109 point to a binary transitional pulsar candidate currently in a sub-luminous accretion disk state, and that the upper limits derived for the radio emission are consistent with the expected radio luminosity for accreting neutron stars at similar X-ray luminosities.
Marine fungi remain poorly covered in global genome sequencing campaigns; the 1000 fungal genomes (1KFG) project attempts to shed light on the diversity, ecology and potential industrial use of ...overlooked and poorly resolved fungal taxa. This study characterizes the genomes of three marine fungi: Emericellopsis sp. TS7, wood-associated Amylocarpus encephaloides and algae-associated Calycina marina. These species were genome sequenced to study their genomic features, biosynthetic potential and phylogenetic placement using multilocus data. Amylocarpus encephaloides and C. marina were placed in the Helotiaceae and Pezizellaceae (Helotiales), respectively, based on a 15-gene phylogenetic analysis. These two genomes had fewer biosynthetic gene clusters (BGCs) and carbohydrate active enzymes (CAZymes) than Emericellopsis sp. TS7 isolate. Emericellopsis sp. TS7 (Hypocreales, Ascomycota) was isolated from the sponge Stelletta normani. A six-gene phylogenetic analysis placed the isolate in the marine Emericellopsis clade and morphological examination confirmed that the isolate represents a new species, which is described here as E. atlantica. Analysis of its CAZyme repertoire and a culturing experiment on three marine and one terrestrial substrates indicated that E. atlantica is a psychrotrophic generalist fungus that is able to degrade several types of marine biomass. FungiSMASH analysis revealed the presence of 35 BGCs including, eight non-ribosomal peptide synthases (NRPSs), six NRPS-like, six polyketide synthases, nine terpenes and six hybrid, mixed or other clusters. Of these BGCs, only five were homologous with characterized BGCs. The presence of unknown BGCs sets and large CAZyme repertoire set stage for further investigations of E. atlantica. The Pezizellaceae genome and the genome of the monotypic Amylocarpus genus represent the first published genomes of filamentous fungi that are restricted in their occurrence to the marine habitat and form thus a valuable resource for the community that can be used in studying ecological adaptions of fungi using comparative genomics.
The development of left ventricular systolic dysfunction (LVSD) in hypertrophic cardiomyopathy (HCM) is rare but serious and associated with poor outcomes in adults. Little is known about the ...prevalence, predictors, and prognosis of LVSD in patients diagnosed with HCM as children.
Data from patients with HCM in the international, multicenter SHaRe (Sarcomeric Human Cardiomyopathy Registry) were analyzed. LVSD was defined as left ventricular ejection fraction <50% on echocardiographic reports. Prognosis was assessed by a composite of death, cardiac transplantation, and left ventricular assist device implantation. Predictors of developing incident LVSD and subsequent prognosis with LVSD were assessed using Cox proportional hazards models.
We studied 1010 patients diagnosed with HCM during childhood (<18 years of age) and compared them with 6741 patients with HCM diagnosed as adults. In the pediatric HCM cohort, median age at HCM diagnosis was 12.7 years (interquartile range, 8.0-15.3), and 393 (36%) patients were female. At initial SHaRe site evaluation, 56 (5.5%) patients with childhood-diagnosed HCM had prevalent LVSD, and 92 (9.1%) developed incident LVSD during a median follow-up of 5.5 years. Overall LVSD prevalence was 14.7% compared with 8.7% in patients with adult-diagnosed HCM. Median age at incident LVSD was 32.6 years (interquartile range, 21.3-41.6) for the pediatric cohort and 57.2 years (interquartile range, 47.3-66.5) for the adult cohort. Predictors of developing incident LVSD in childhood-diagnosed HCM included age <12 years at HCM diagnosis (hazard ratio HR, 1.72 CI, 1.13-2.62), male sex (HR, 3.1 CI, 1.88-5.2), carrying a pathogenic sarcomere variant (HR, 2.19 CI, 1.08-4.4), previous septal reduction therapy (HR, 2.34 CI, 1.42-3.9), and lower initial left ventricular ejection fraction (HR, 1.53 CI, 1.38-1.69 per 5% decrease). Forty percent of patients with LVSD and HCM diagnosed during childhood met the composite outcome, with higher rates in female participants (HR, 2.60 CI, 1.41-4.78) and patients with a left ventricular ejection fraction <35% (HR, 3.76 2.16-6.52).
Patients with childhood-diagnosed HCM have a significantly higher lifetime risk of developing LVSD, and LVSD emerges earlier than for patients with adult-diagnosed HCM. Regardless of age at diagnosis with HCM or LVSD, the prognosis with LVSD is poor, warranting careful surveillance for LVSD, especially as children with HCM transition to adult care.
The incidence and properties of present-day dwarf galaxies hosting massive black holes (BHs) can provide important constraints on the origin of high-redshift BH seeds. Here we present high-resolution ...X-ray and radio observations of the low-metallicity, star-forming, dwarf-galaxy system Mrk 709 with the Chandra X-ray Observatory and the Karl G. Jansky Very Large Array. These data reveal spatially coincident hard X-ray and radio point sources with luminosities suggesting the presence of an accreting massive BH (M sub(BH) ~ 10 super(5-7) M sub(middot in circle)). Based on imaging from the Sloan Digital Sky Survey (SDSS), we find that Mrk 709 consists of a pair of compact dwarf galaxies that appear to be interacting with one another. The position of the candidate massive BH is consistent with the optical center of the southern galaxy (Mrk 709 S), while no evidence for an active BH is seen in the northern galaxy (Mrk 709 N). We derive stellar masses of Mlow * ~ 2.5 x 10 super(9)M sub(middot in circle) and Mlow * ~ 1.1 x 10 super(9) M sub(middot in circle) for Mrk 709 S and Mrk 709 N, respectively, and present an analysis of the SDSS spectrum of the BH host Mrk 709 S. At a metallicity of just ~10% solar, Mrk 709 is among the most metal-poor galaxies with evidence for an active galactic nucleus. Moreover, this discovery adds to the growing body of evidence that massive BHs can form in dwarf galaxies and that deep, high-resolution X-ray and radio observations are ideally suited to reveal accreting massive BHs hidden at optical wavelengths.