We present an extensive experimental study of the recently predicted pygmy quadrupole resonance (PQR) in Sn isotopes, where complementary probes were used. In this study, (α,α′γ) and (γ,γ′) ...experiments were performed on 124Sn. In both reactions, Jπ=2+ states below an excitation energy of 5 MeV were populated. The E2 strength integrated over the full transition densities could be extracted from the (γ,γ′) experiment, while the (α,α′γ) experiment at the chosen kinematics strongly favors the excitation of surface modes because of the strong α-particle absorption in the nuclear interior. The excitation of such modes is in accordance with the quadrupole-type oscillation of the neutron skin predicted by a microscopic approach based on self-consistent density functional theory and the quasiparticle-phonon model (QPM). The newly determined γ-decay branching ratios hint at a non-statistical character of the E2 strength, as it has also been recently pointed out for the case of the pygmy dipole resonance (PDR). This allows us to distinguish between PQR-type and multiphonon excitations and, consequently, supports the recent first experimental indications of a PQR in 124Sn.
A new plunger device has been designed and built to measure the lifetimes of unbound states in exotic nuclei beyond the proton drip-line. The device has been designed to work in both vacuum and ...dilute-gas environments made possible through the introduction of a low-voltage stepping motor. DPUNS will be used in conjunction with the gas-filled separator RITU and the vacuum separator MARA at the accelerator laboratory of the University of Jyväskylä, Finland, to measure the lifetimes of excited states with low population cross-sections. This is achieved by eliminating the need for a carbon foil to isolate the helium gas of RITU from the beam line thus reducing the background from beam-foil reactions. The inclusion of a high-sampling rate data acquisition card increases further the sensitivity of the device. The plunger will be used to address many key facets of nuclear structure physics with particular emphasis on the effect of deformation on proton emission rates.
We present 3D thermal and rheological models of a key intra-plate locality of South America: the southernmost limit of the Río de la Plata Craton area (which encompasses the Claromecó Basin, the ...Sierras Australes, and the Colorado Basin). Both models were calculated on the basis of a previously published 3D lithospheric scale density model, after the population of the different units with thermal and rheological properties. Firstly, the steady-state conductive thermal field was modelled using different thermal properties in accordance with the assumed lithological composition of the units. Moving forward, the strength distribution was calculated considering the resulting thermal field and published rheological properties for common rock types as input for the different layers that compose the 3D density configuration of the area. Our main results suggest that the thickness and composition of the crust exert a first-order control on the present-day thermal field of the area and, subsequently, on the lithospheric strength. Particularly, we identified a rheologically weak lithospheric zone that coincides with previously proposed inherited Paleozoic structures of Gondwana. This inherited lithospheric fabric could have controlled the opening of the Colorado Rift Basin during the early Late Jurassic. In that sense, the present day high strength of the Rio Negro and Colorado transfer zones associated with the mafic infill of Colorado rifting in the Mesozoic suggests that the weak zones should have necessarily been developed during (at least) Paleozoic to early Mesozoic times. This supports the hypothesis that the reactivation and interaction of the latter with the Gondwanic weak lithospheric zone could have deformed and uplifted the Sierras Australes during the Gondwanides Orogeny.
Background:
Symptom tracking for endometriosis has been validated with clinical benefits, however, there is limited evidence around the use of mobile apps for endometriosis symptom tracking.
Method:
...We performed a survey of people with suspected or confirmed endometriosis in Aotearoa New Zealand to assess mobile app use for symptom tracking including which app is being used, how frequently symptoms are tracked, which features are most important and which features would be desired. We also explored willingness to share symptom data with clinicians and/or researchers.
Results:
A total of 188 survey responses were included. Mobile apps were used for symptom tracking by 83/188 (44.1%), with only 13 of 188 (6.9%) reporting they would not consider use of an app. Of current app users, 51.5% reported logging symptoms at least weekly. The most frequently desired features included tracking of specific symptoms (such as periods, pain, bowel symptoms, mental health symptoms), other tracking (such as medications and diet) and general app usability. Of those who use or would consider using an app 77.7% reported they would be comfortable sharing data with clinicians, and 76.1% reported they would be comfortable sharing anonymous data with researchers.
Discussion:
Almost half of participants reported using an app to track symptoms, and almost all reported they would consider use. Around three in four patients would be willing to share this data with clinicians and researchers, and therefore further focus on the utility of these apps may benefit patients directly, their relationship with healthcare providers and be utilised for further endometriosis research.
Surgical site infection (SSI) following caesarean section is common, resulting in significant morbidity. Several factors are known to contribute to wound infection, including maternal, procedural and ...antibiotic factors. We sought to clarify these issues and sought opportunities to make improvements. A retrospective cohort study was performed assessing all women who underwent caesarean section in 2014 and 2015 at Wellington Hospital. Any women with culture‐positive wound samples within 30 days of surgery were identified, and clinical notes reviewed. Odds ratios (OR) were calculated for available maternal, procedural and antibiotic risk factors. Two simplified surveillance techniques were also tested for their abilities to identify significant trends. The study included 2231 women, of whom 116 (5.2%) were identified as having SSI. Maternal obesity (body mass index (BMI) ≥ 30) was associated with significant SSI risk (OR 4.1, P < 0.001). The pathogen distribution was significantly different between women with BMI < 30 and BMI ≥ 30 (P < 0.001). Increased cefazolin dose based on BMI (3 g dose for BMI ≥ 30) was associated with a significant reduction in SSI (OR 0.309, P < 0.001) and was administered in 74.1% of obese women receiving cefazolin. Māori women had an increased SSI risk (OR 2.1, P = 0.019), as did Samoan women (OR 3.0, P = 0.002). The study reinforces other studies showing that raised BMI is the single biggest risk factor for surgical site infection post‐caesarean section. Surveillance using simplified techniques appears to be adequate to identify trends. We believe that concentrating on appropriate antibiotic dosing and targeting special wound care measures will be pivotal interventions in improving outcomes in high‐risk groups.
Multidisciplinary studies of geotransects across the North European Plain and Southern North Sea, and geological reexamination of the Variscides of the North Bohemian Massif, permit a new 3-D ...reassessment of the relationships between the principal crustal blocks abutting Baltica along the Trans-European Suture Zone (TESZ). Accretion was in three stages: Cambrian accretion of the Bruno–Silesian, Lysogory and Malopolska terranes; end-Ordovician/early Silurian accretion of Avalonia; and early Carboniferous accretion of the Armorican Terrane Assemblage (ATA). Palaeozoic plume-influenced metabasite geochemistry in the Bohemian Massif explains the progressive rifting away of peri-Gondwanan crustal blocks before their accretion to Baltica. Geophysical data, faunal and provenance information from boreholes, and dated small inliers and cores confirm that Avalonian crust extends beyond the Anglo-Brabant Deformation Belt eastwards to northwest Poland. The location and dip of reflectors along the TESZ and beneath the North European Plain suggest that Avalonian crust overrode the Baltica passive margin, marked by a high-velocity lower crustal layer, on shallowly southwest-dipping thrust planes forming the Heligoland–Pomerania Deformation Belt. The “Variscan orocline” of southwest Poland masks two junctions between the Armorican Terrane Assemblage (ATA) and previously accreted crustal blocks. To the east is a dextrally transpressive contact with the Bruno–Silesian and Malopolska blocks, accreted in the Cambrian, while to the north is a thrust contact with easternmost Avalonia, deeply buried beneath younger sedimentary cover. In the northeast Bohemian and Rhenohercynian Massifs Devonian “early Variscide” deformation dominated by WNW and NW-directed thrusting, records closure of Ordovician–Devonian seaways between detached “islands” of the ATA and Avalonia.
The Central European Basin System (CEBS) is composed of a series of subbasins, the largest of which are (1) the Norwegian–Danish Basin (2), the North German Basin extending westward into the southern ...North Sea and (3) the Polish Basin. A 3D structural model of the CEBS is presented, which integrates the thickness of the crust below the Permian and five layers representing the Permian–Cenozoic sediments. Structural interpretations derived from the 3D model and from backstripping are discussed with respect to published seismic data. The analysis of structural relationships across the CEBS suggests that basin evolution was controlled to a large degree by the presence of major zones of crustal weakness. The NW–SE-striking Tornquist Zone, the Ringkøbing-Fyn High (RFH) and the Elbe Fault System (EFS) provided the borders for the large Permo–Mesozoic basins, which developed along axes parallel to these fault systems. The Tornquist Zone, as the most prominent of these zones, limited the area affected by Permian–Cenozoic subsidence to the north. Movements along the Tornquist Zone, the margins of the Ringkøbing-Fyn High and the Elbe Fault System could have influenced basin initiation. Thermal destabilization of the crust between the major NW–SE-striking fault systems, however, was a second factor controlling the initiation and subsidence in the Permo–Mesozoic basins. In the Triassic, a change of the regional stress field caused the formation of large grabens (Central Graben, Horn Graben, Glückstadt Graben) perpendicular to the Tornquist Zone, the Ringkøbing-Fyn High and the Elbe Fault System. The resulting subsidence pattern can be explained by a superposition of declining thermal subsidence and regional extension. This led to a dissection of the Ringkøbing-Fyn High, resulting in offsets of the older NW–SE elements by the younger N–S elements. In the Late Cretaceous, the NW–SE elements were reactivated during compression, the direction of which was such that it did not favour inversion of N–S elements. A distinct change in subsidence controlling factors led to a shift of the main depocentre to the central North Sea in the Cenozoic. In this last phase, N–S-striking structures in the North Sea and NW–SE-striking structures in The Netherlands are reactivated as subsidence areas which are in line with the direction of present maximum compression. The Moho topography below the CEBS varies over a wide range. Below the N–S-trending Cenozoic depocentre in the North Sea, the crust is only 20 km thick compared to about 30 km below the largest part of the CEBS. The crust is up to 40 km thick below the Ringkøbing-Fyn High and up to 45 km along the Teisseyre–Tornquist Zone. Crustal thickness gradients are present across the Tornquist Zone and across the borders of the Ringkøbing-Fyn High but not across the Elbe Fault System. The N–S-striking structural elements are generally underlain by a thinner crust than the other parts of the CEBS.
The main fault systems in the Permian to Cenozoic sediment fill of the CEBS are located above zones in the deeper crust across which a change in geophysical properties as P-wave velocities or gravimetric response is observed. This indicates that these structures served as templates in the crustal memory and that the prerift configuration of the continental crust is a major controlling factor for the subsequent basin evolution.
Aim
Preterm birth is associated with an increased risk of adverse neurodevelopmental outcomes. Diffusion magnetic resonance imaging (dMRI) combined with tractography can be used to assess ...non‐invasively white matter microstructure and brain development in preterm infants. Our aim was to conduct a systematic review of the current evidence obtained from tractography studies of preterm infants in whom MRI was performed up to term‐equivalent age.
Method
Databases were searched for dMRI tractography studies of preterm infants.
Results
Twenty‐two studies were assessed. The most frequently assessed tracts included the corticospinal tract, the corpus callosum, and the optic radiations. The superior longitudinal fasciculus, and the anterior and superior thalamic radiations were investigated less frequently. A clear relationship exists between diffusion metrics and postmenstrual age at the time of scanning, although the evidence of an effect of gestational age at birth and white matter injury is conflicting. Sex and laterality may play an important role in the relationship between diffusion metrics, early clinical assessment, and outcomes.
Interpretation
Studies involving infants of all gestational ages are required to elucidate the relationship between gestational age and diffusion metrics, and to establish the utility of tractography as a predictive tool. There is a need for more robust acquisition and analysis methods to improve the accuracy of assessing development of white matter pathways.
What this paper adds
There is clear evidence of an effect of PMA on diffusion metrics.
The effects of gestational age and white matter injury on diffusion are inconclusive.
The suitability of tractography as a predictive tool needs to be investigated further.
A need for robust acquisition and analysis was identified.
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