Because of the differing opinions on the value of glucagon and the best way of administering it in severe hypoglycaemia induced by sulphonylurea drugs, experiments were conducted on normal subjects, ...and in diabetic patients before and during treatment with chlorpropamide. In all subjects glucagon raised blood sugar concentrations, and produced a greater and more prolonged increase in blood glucose concentrations when given intramuscularly than when given intravenously. Hypoglycaemia did not occur in any subject.
Valproate is an effective anticonvulsant which is rarely associated with hepatotoxicity. It has profound effects on the intermediary metabolism of isolated rat hepatocytes. In this paper the effect ...of valproate on blood metabolite concentrations in spontaneously diabetic BB/E rats has been studied. Valproate causes a marked fall in blood ketone body concentrations and a smaller fall in blood glucose concentrations following either oral or intraperitoneal administration. Valproate may have a role in the treatment of patients with "brittle" diabetes.
Questo progetto è diretto allo studio del paesaggio rurale intorno alla città di Rieti, nell'Italia centrale e in particolare si propone di esaminare, in un ampio fronte diacronico, il mutamento del ...modello insediamentale e i diversi modi di sfruttamento dell'alto bacino appenninico e delle colline e dei monti circostanti. Sono qui descritti gli scopi ed i metodi interdisciplinari del progetto e vengono riportati i principali risultati ottenuti. Lo studio degli aspetti geomorfologici ha giocato un ruolo importante nel progetto e i risultati sono presentati in due principali sezioni riguardanti una la natura dei suoli del bacino e l'altra i diversi modi della loro formazione. Il lavoro sul campo si è principalmente basato sulla ricognizione intensiva di una serie di transetti perpendicolari sul lato orientale del bacino montano di Rieti, estesa anche alle montagne circostanti. Nel corso di tre stagioni di lavoro, oltre 500 campi sono stati esaminati nell'ambito di un'area di circa 22 kmq., insieme con più ampie ricognizioni all'interno dell'intero bacino; tali ricognizioni sono state specificatamente finalizzate alla ricerca di dati che aiutassero a fornire risposte circa la problematica riguardante il mutare del quadro insediativo durante l'epoca medievale. Sono stati rinvenuti un totale di circa 200 siti di vario tipo ed epoca, sebbene si sia cercato di analizzare tali siti, durante le ricognizioni, nell'ambito dell'archeologia off-site. Le ricognizioni di particolari aree comprendenti un certo numero di siti con evidenti resti architettonici, sono state integrate con le evidenze portate alla superficie tramite l'aratura. Le ricognizioni miranti al rinvenimento di strutture sono risultate essere particolarmente positive, con l'individuazione di una serie di castelli e villaggi medievali, posizionati ad alte quote intorno al bacino. Durante tale progetto sono stati inoltre usati metodi geofisici di prospezione, compiendo ricognizione di resistività su larga scala per circa 20 siti: vengono qui riportati alcuni commenti preliminari sui risultati ottenuti grazie a questa tecnica. Il lavoro di tipo archeologico è stato accompagnato da una ricerca a carattere storico ed archivistico; l'articolo si conclude con una sintesi della storia insediamentale del bacino di Rieti per un periodo che va dall'età del bronzo all'età post-medievale.
Junior Hospital Staff Contract Ahmad, A. J.; Barnes, P. J.; Bentham, V. ...
British Medical Journal,
07/1975, Letnik:
3, Številka:
5974
Journal Article
Analysis of plasmid ColE1, its naturally occurring relatives ColK and CloDF13, and a wide range of ColE1 derivatives containing either insertions or deletions of genetic material has allowed ...localization on the ColE1 genome of DNA sequences responsible for colicin E1 synthesis, immunity to colicin killing, conjugal mobility and incompatibility. We have examined incompatibility between pairs of ColE1 derivatives ranging in size from 2.6 to 13.8 Md. Though all the plasmids tested exerted ColE1 incompatibility, a definite pattern was observed regarding the dominant plasmid in any pair tested (i.e. the plasmid that displaces the other from a heterozygote). Usually the larger plasmid is displaced. We conclude that loci for incompatibility reside within 0.7 kb of the ColE1 replication region. A model is presented to explain both the incompatibility data and the observation that the fraction of total DNA occurring as ColE1-like plasmid in a cell is approximately constant. Transposons Tn1 and Tn3 (3.2 Md; Apr and approximately 85% homologous), Tn501 (5.5 Md; Hgr), and Tn7 (9.3 Md; Tpr Smr) can all be transposed into ColE1. Though all have closely related. Tn501 and Tn7 do not complement transposition of Tn3 transposition defective deletions. A Tn3-specified 19,000 dalton protein is absent in one particular class of transposition-defective deletion.
Replication of plasmid supercoiled DNA Helinski, D R; Blair, D G; Sherratt, D J ...
Johns Hopkins medical journal. Supplement,
1973, Letnik:
2
Journal Article
Reviews of Books Sherratt, Andrew; Graff, David A.; Eckstein, Arthur M. ...
The International History Review,
20/9/1/, Letnik:
24, Številka:
3
Book Review
Recenzirano
Barry Cunliffe. Facing the Ocean: The Atlantic and Its Peoples, 8000 BC-AD 1500. New York: Oxford University Press, 2001. Pp. viii, 600. $56.00 (CDN). Reviewed by Andrew Sherratt
Charles Holcombe. ...The Genesis of East Asia, 221 BC-AD 907. Honolulu: University of Hawaii Press, 2001. Pp. viii, 332. $24.95 (US)i paper. Reviewed by David A. Graff
J. H. C. Williams. Beyond the Rubicon: Romans and Gauls in Republican Italy. New York: Oxford University Press, 2001. Pp. xiii, 264. $106.00 (CDN). Reviewed by Arthur M. Eckstein
Wilhelm Baum. Äthiopien und der Westen im Mittelalter: Die Selbstbehauptung der christlichen Kultur am oberen Nil zwischen dem islamischen Orient und dem europàischen Kolonialismus. Klagenfurt: Verlag Kitab, 2001. Pp. 280. €25.00, paper. Reviewed by Donald Crummey
Florin Curta. The Making of the Slavs: History and Archaeology of the Lower Danube Region, c. 500-700. New York: Cambridge University Press, 2001. Pp. xxv, 463. $80.00 (US). Reviewed by Paul Stephenson
Uta-Renate Blumenthal. Gregor VII: Papst zwischen Canossa und Kirchenreform. Darmstadt: Primus Verlag, 2001. Pp. xiii, 376. €29.90. Reviewed by Timothy Reuter
MacGregor Knox and Williamson Murray, eds. The Dynamics of Military Revolution, 1300-2050. New York: Cambridge University Press, 2001. Pp. xiv, 203. $27.95 (US); Stig Förster, Markus Pöhlmann, and Dierk Walter, eds. Schlachten der Weltgeschichte: Von Salamis bis Sinai. Munich: C. H. Beck, 2001. Pp. 414. €24.90. Reviewed by Jeremy Black
Richard Butterwick, ed. The Polish-Lithuanian Monarchy in European Context, c. 1500-1795. Basingstoke and New York: Palgrave, 2001. Pp. xix, 249. $65.00 (US). Reviewed by Robert E. Jones
Jos Gommans, Lennart Bes, and Gus Kruijtzer. Dutch Sources on South Asia c. 1600-1825: I: Bibliography and Archival Guide to the National Archives at The Hague (The Netherlands). New Delhi: Manohar, 2001. Pp. 424. Rs 750. Reviewed by P.J.Marshall
Reinier H. Hesselink. Prisoners from Nambu: Reality and Make-Believe in Seventeenth-Century Japanese Diplomacy. Honolulu: University of Hawaii Press, 2002. Pp. xii, 215. $24.95 (US), paper. Reviewed by Derek Massarella
Geoffrey Plank. An Unsettled Conquest: The British Campaign against the Peoples of Acadia. Philadelphia: University of Pennsylvania Press, 2001; dist. Toronto: Scholarly Book Services. Pp. 239. $45.95 (CDN). Reviewed by K. David Milobar
Bruny D'Entrecasteaux. Voyage to Australia and the Pacific, 1791-1793, ed. and trans. Edward Duyker and Maryse Duyker. Melbourne: Melbourne University Press, 2001. Pp. xliii, 392. $59.95 (AUS). Reviewed by Glyndwr Williams
Lawrence Sondhaus. Naval Warfare, 1815-1914. London and New York: Routledge, 2001. Pp. viii, 263. $85.00 (US), cloth; $25.95 (US)i paper. Reviewed by C. I. Hamilton
J. I. Little, ed. Love Strong as Death: Lucy Peel's Canadian Journal, 1833-1836. Waterloo: Wilfrid Laurier University Press, 2001. Pp. x, 229. $39.95 (CDN). Reviewed by Marguerite van Die
Alan Lester. Imperial Networks: Creating Identities in Nineteenth-Century South Africa and Britain. London and New York: Routledge, 2001. Pp. x, 257. $16.99 (US), paper. Reviewed by Norman Etherington
Peter H. Hoffenberg. An Empire on Display: English, Indian, and Australian Exhibitions from the Crystal Palace to the Great War. Berkeley and Los Angeles: University of California Press, 2001. Pp. xxvii, 418. $50.00 (US). Reviewed by Catherine Hall
E. A. Porcher. A Tour of Duty in the Pacific Northwest: E. A. Porcher and HMS Sparrowhawk, 1865-1868, ed. and annotated Dwight L. Smith. Fairbanks: University of Alaska Press, 2000. Pp. xvii, 172. $34.95 (US). Reviewed by Roger Sarty
David Schimmelpenninck van der Oye. Toward the Rising Sun: Russian Ideologies of Empire and the Path to War with Japan. DeKalb: Northern Illinois University Press, 2001. Pp. xiii, 239. $40.00 (US). Reviewed by Paul Dukes
David Wetzel. A Duel of Giants: Bismarck, Napoleon HI, and the Origins of the Franco-Prussian War. Madison: University of Wisconsin Press, 2001. Pp. xvi, 244. $24.95 (US). Reviewed by Michael Schmid
Colin Dyer, ed. and trans. A Frenchman's Walk across the Nullarbor: Henri Gilbert's Diary, Perth to Brisbane, 1897-1899. Melbourne: Melbourne University Press, 2000; dist. Chicago: Paul & Company. Pp. xii, 195. $24.95 (US). Reviewed by Geoffrey Bolton
Kamakshi P. Murti. India: The Seductive and Seduced 'Other' of German Orientalism. Westport: Greenwood Press, 2001. Pp. 149. $55.00 (US). Reviewed by Dorothy Figueira
Chris Youé and Tim Stapleton, eds. Agency and Action in Colonial Africa: Essays for John E. Flint. Basingstoke and New York: Palgrave, 2001. Pp. x, 219. $60.00 (US). Reviewed by Ralph A. Austen
Ben Shephard. A War of Nerves: Soldiers and Psychiatrists in the Twentieth Century. Cambridge, Mass, and London: Harvard University Press, 2001. Pp. xxiii, 487. $27.95 (US). Reviewed by Robert J. T. Joy
Yoshihisa Tak Matsusaka. The Making of Japanese Manchuria, 1904-1932. Cambridge, Mass, and London: Harvard University Press, 2001. Pp. xviii, 522. $49.50 (US). Reviewed by Rana Mitter
Rosemary O'brien, ed. Gertrude Bell: The Arabian Diaries, 1913-1914. Syracuse: Syracuse University Press, 2000. Pp. xv, 258. $29.95 (US)- Reviewed by William L. Cleveland
Gary Sheffield. Forgotten Victory: The First World War: Myths and Realities. London: Headline, 2001. Pp. xix, 298. £20.00. Reviewed by David French
Norman E. Saul. War and Revolution: The United States and Russia, 1914-1921. Lawrence: University Press of Kansas, 2001. Pp. xx, 483. $45.00 (US). Reviewed by Michael Jabara Carley
John C. Swanson. The Remnants of the Habsburg Monarchy: The Shaping of Modern Austria and Hungary, 1918-1922. Boulder: East European Monographs, 2001; dist. New York: Columbia University Press. Pp. vii, 391. $32.00 (US). Reviewed by Jeremy King
David Dutton, ed. Paris 1918: The War Diary of the British Ambassador, the 17th Earl of Derby. Liverpool: Liverpool University Press, 2001; dist. Pordand: ISBS. Pp. xxxvi, 348. $69.95 (vs)i cloth; $28.95 (US), paper. Reviewed by Alan Sharp
Silke Neunsinger. Die Arbeit der Frauen - aie Krise der Manner: Die Erwerbstatigkeit verheirateter Frauen in Deutschland und Schweden 1919-1939. Uppsala: Uppsala University Library, 2001. Pp. 294. Full text can be downloaded from http://publications.uu.se/theses/fulltext/91-554-5088-1.pdf Reviewed by Peter D. Stachura
Antony Lentin. Lloyd George and the Lost Peace: From Versailles to Hitler, 1919-1940. Basingstoke and New York: Palgrave, 2001. Pp. xvii, 182. $60.00 (US). Reviewed by Michael Graham Fry
Michael Dockrill and John Fisher, eds. The Paris Peace Conference, 1919: Peace without Victory? Basingstoke and New York: Palgrave, 2001. Pp. xiv, 197. $55.00 (US). Reviewed by G. H. Bennett
David F. Schmitz. Henry L. Stimson: The First Wise Man. Wilmington: Scholarly Resources, 2001. Pp. xxiii, 222. $17.95 (US). paper; Margot Louria. Triumph and Downfall: America's Pursuit of Peace and Prosperity, 1921-1933. Westport: Greenwood Press, 2001. Pp. viii, 267. $62.50 (US). Reviewed by Robert Freeman Smith
Izumi Hirobe. Japanese Pride, American Prejudice: Modifying the Exclusion Clause of the 1924 Immigration Act. Stanford: Stanford University Press, 2001. Pp. xiii, 327. $49.50 (US). Reviewed by Eileen P. Scully
Michael Wala. Weimar und Amerika: Botschafter Friedrich von Prittwitz und Gaffron und die deutsch-amerikanischen Beziehungen von 1927 bis 1933. Stuttgart: Franz Steiner Verlag, 2001. Pp. 341. €38.00. Reviewed by William Patch
István Deák. Essays on Hitler's Europe. Lincoln and London: University of Nebraska Press, 2001. Pp. xviii, 222. $24.95 (US)i paper. Reviewed by Gerhard L. Weinberg
Bat-Ami Zucker. In Search of Refuge: Jews and US Consuls in Nazi Germany, 1933-1941. London: Vallentine Mitchell, 2001; dist. Portland: ISBS. Pp. xiv, 229. $49.50 (US). Reviewed by Leonard Dinnerstein
Russell A. Hart. Clash of Arms: How the Allies Won in Normandy. Boulder: Lynne Rienner, 2001. Pp. xviii, 469. $79.95 (US). Reviewed by Tim Harrison Place
Christian Leitz. Sympathy for the Devil: Neutral Europe and Nazi Germany in World War II. New York: New York University Press, 2001. Pp. 213. $40.00 (US). Reviewed by Wayne H. Bowen
Henry Probert. Bomber Harris: His Life and Times: The Biography of Marshal of the Royal Air Force, Sir Arthur Harris, the Wartime Chief of Bomber Command. London and Mechanicsburg: Greenhill Books and Stackpole Books, 2001. Pp. 432. £25.00. Reviewed by Conrad C. Crane
Greg Robinson. By Order of the President: FDR and the Internment of Japanese Americans. Cambridge, Mass, and London: Harvard University Press, 2001. Pp. 322. $27.95 (US). Reviewed by Wesley T. Wooley
John Willoughby. Remaking the Conquering Heroes: Post-War American Occupation of Germany. Basingstoke and New York: Palgrave, 2001. Pp. xiii, 187. $45.00 (US). Reviewed by Petra Goedde
Frank Schumacher. Kalter Krieg und Propaganda: Die USA, der Kampfum die Weltmeinung und die ideelle Westbindung der Bundesrepublik Deutschland, 1945-1955. Trier: Wissenschaftlicher Verlag, 2000. Pp. 332. €33.00, paper. Reviewed by Erich J. Hahn
Mark Smith. NATO Enlargement during the Cold War: Strategy and System in the Western Alliance. Basingstoke and New York: Palgrave, 2000. Pp. x, 207. $65.00 (US); Ekavi Athanassopoulou. Turkey - Anglo-American Security Interests, 1945-1952: The First Enlargement of NATO. London and Portland: Frank Cass, 1999. Pp. xiii, 274. $59.50 (US). Reviewed by Ames Sperling
Mary Fulbrook, ed. Europe since 1945. New York: Oxford University Press, 2001. Pp. xv, 324. $34.95 (CDN). Reviewed by John Gillingham
Melani McAlister. Epic Encounters: Culture, Media, and US Interests in the Middle East, 1945-2000. Berkeley and Los Angeles: University of California Press, 2001. Pp. xv, 358. $19.95 (US), paper. Reviewed by Peter L. Hahn
Paul Schneeberger. Der schwierige Umgang mit dem Anschluss: Die Rezeption in Geschichtsdarstellungen, 1946-1995. Innsbruck: Studien Verlag, 2000. Pp. 568. €52.00, paper. Reviewed by Dieter