Abstract
We measure the evolution of the X-ray luminosity-temperature (L
X − T) relation since z ∼ 1.5 using a sample of 211 serendipitously detected galaxy clusters with spectroscopic redshifts ...drawn from the XMM Cluster Survey first data release (XCS-DR1). This is the first study spanning this redshift range using a single, large, homogeneous cluster sample. Using an orthogonal regression technique, we find no evidence for evolution in the slope or intrinsic scatter of the relation since z ∼ 1.5, finding both to be consistent with previous measurements at z ∼ 0.1. However, the normalization is seen to evolve negatively with respect to the self-similar expectation: we find E
−1(z) L
X = 1044.67 ± 0.09(T/5)3.04 ± 0.16(1 + z)−1.5 ± 0.5, which is within 2σ of the zero evolution case. We see milder, but still negative, evolution with respect to self-similar when using a bisector regression technique. We compare our results to numerical simulations, where we fit simulated cluster samples using the same methods used on the XCS data. Our data favour models in which the majority of the excess entropy required to explain the slope of the L
X − T relation is injected at high redshift. Simulations in which active galactic nucleus feedback is implemented using prescriptions from current semi-analytic galaxy formation models predict the positive evolution of the normalization, and differ from our data at more than 5σ. This suggests that more efficient feedback at high redshift may be needed in these models.
To date only a fraction of the genetic footprint of thyroid function has been clarified. We report a genome-wide association study meta-analysis of thyroid function in up to 271,040 individuals of ...European ancestry, including reference range thyrotropin (TSH), free thyroxine (FT4), free and total triiodothyronine (T3), proxies for metabolism (T3/FT4 ratio) as well as dichotomized high and low TSH levels. We revealed 259 independent significant associations for TSH (61% novel), 85 for FT4 (67% novel), and 62 novel signals for the T3 related traits. The loci explained 14.1%, 6.0%, 9.5% and 1.1% of the total variation in TSH, FT4, total T3 and free T3 concentrations, respectively. Genetic correlations indicate that TSH associated loci reflect the thyroid function determined by free T3, whereas the FT4 associations represent the thyroid hormone metabolism. Polygenic risk score and Mendelian randomization analyses showed the effects of genetically determined variation in thyroid function on various clinical outcomes, including cardiovascular risk factors and diseases, autoimmune diseases, and cancer. In conclusion, our results improve the understanding of thyroid hormone physiology and highlight the pleiotropic effects of thyroid function on various diseases.
Human virtual atrial tissues and atria are constructed that quantitatively describe atrial fibrillation and remodelling, and the actions of anti-arrhythmic agents.
Computational models of human ...atrial cells, tissues and atria have been developed. Cell models, for atrial wall, crista terminalis, appendage, Bachmann’s bundle and pectinate myocytes are characterised by action potentials, ionic currents and action potential duration (APD) restitution. The principal effect of the ion channel remodelling of persistent atrial fibrillation (AF), and a mutation producing familial AF, was APD shortening at all rates. Electrical alternans was abolished by the modelled action of Dronedarone. AF induced gap junctional remodelling slows propagation velocity at all rates. Re-entrant spiral waves in 2-D models are characterised by their frequency, wavelength, meander and stability. For homogenous models of normal tissue, spiral waves self-terminate, due to meander to inexcitable boundaries, and by dissipation of excitation. AF electrical remodelling in these homogenous models led to persistence of spiral waves, and AF fibrotic remodelling to their breakdown into fibrillatory activity. An anatomical model of the atria was partially validated by the activation times of normal sinus rhythm. The use of tissue geometry from clinical MRI, and tissue anisotropy from ex vivo diffusion tensor magnetic resonance imaging is outlined. In the homogenous model of normal atria, a single scroll breaks down onto spatio-temporal irregularity (electrical fibrillation) that is self-terminating; while in the AF remodelled atria the fibrillatory activity is persistent. The persistence of electrical AF can be dissected in the model in terms of ion channel and intercellular coupling processes, that can be modified pharmacologically; the effects of anatomy, that can be modified by ablation; and the permanent effects of fibrosis, that need to be prevented.
We present a comprehensive analysis of the ability of current stellar population models to reproduce the optical (ugriz) and near-infrared (JHK) colours of a small sample of well-studied nearby ...elliptical and S0 galaxies. We find broad agreement between the ages and metallicities derived using different population models, although different models show different systematic deviations from the measured broad-band fluxes. Although it is possible to constrain simple stellar population models to a well-defined area in age–metallicity space, there is a clear degeneracy between these parameters even with such a full range of precise colours. The precision to which age and metallicity can be determined independently, using only broad-band photometry with realistic errors, is ΔFe/H≃ 0.18 and Δlog Age ≃ 0.25. To constrain the populations and therefore the star formation history further, it will be necessary to combine broad-band optical–IR photometry with either spectral line indices, or else photometry at wavelengths outside this range.
We present a list of 15 clusters of galaxies, serendipitously detected by the XMM Cluster Survey (XCS), that have a high probability of detection by the Planck satellite. Three of them already appear ...in the Planck Early Sunyaev-Zel'dovich (ESZ) catalogue. The estimation of the Planck detection probability assumes the flat Lambda cold dark matter (ΛCDM) cosmology most compatible with 7-year Wilkinson Microwave Anisotropy Probe (WMAP7) data. It takes into account the XCS selection function and Planck sensitivity, as well as the covariance of the cluster X-ray luminosity, temperature and integrated Comptonization parameter, as a function of cluster mass and redshift, determined by the Millennium gas simulations. We also characterize the properties of the galaxy clusters in the final data release of the XCS that we expect Planck will have detected by the end of its extended mission. Finally, we briefly discuss possible joint applications of the XCS and Planck data.
Ecological stability in the Laurentian Great Lakes has been altered by nonindigenous species, such as the Round Goby Neogobius melanostomus and dreissenid mussels, and by declines in native amphipods ...Diporeia spp. We evaluated whether these changes could influence diet overlap between three benthivorous fishes (Slimy Sculpin Cottus cognatus , Deepwater Sculpin Myoxocephalus thompsonii , and Round Goby) and whether predation on eggs of native species was occurring. We examined diets of fish collected at depths of 69–128 m in Lake Michigan offshore of Frankfort and Muskegon, Michigan, and Two Rivers and Sturgeon Bay, Wisconsin, during January–May 2009 and 2010. Important prey (by dry weight proportion and by percent frequency of occurrence) for Slimy Sculpin were Mysis (0.34; 45%), Diporeia (0.16; 34%), and Limnocalanus macrurus (0.22; 68%); important prey for Deepwater Sculpin were Mysis (0.74; 92%) and Diporeia (0.16; 54%). Round Goby consumed mainly bivalves (i.e., dreissenids: 0.68; 95%) and Mysis (0.15; 37%). The two sculpin species consumed the eggs of Bloaters Coregonus hoyi (Slimy Sculpin: 0.04, 11%; Deepwater Sculpin: 0.02, 7%) and the eggs of Deepwater Sculpin (Slimy Sculpin: 0.03, 13%; Deepwater Sculpin: 0.05, 16%) during February–May at all sites. Round Goby also consumed eggs of these species but at lower levels (≤0.01; <1%). Diet overlap was identified between sculpin species at Frankfort and Sturgeon Bay, suggesting possible interspecific competition, but their diets did not overlap at Two Rivers; diet overlap was never observed between Round Goby and either sculpin species. Given that (1) diet overlap varied by site and (2) diet proportions varied spatially more than temporally, benthivores appear to be exhibiting localized responses to recent ecological changes. Overall, these results reveal that egg predation and interspecific competition could be important interactions to consider in future examinations of the population dynamics of these species or in ecosystem models that forecast how fisheries will respond to possible perturbations or management scenarios. Received April 24, 2012; accepted November 23, 2012
The XMM Cluster Survey (XCS) is a serendipitous search for galaxy clusters using all publicly available data in the XMM-Newton Science Archive. Its main aims are to measure cosmological parameters ...and trace the evolution of X-ray scaling relations. In this paper we present the first data release from the XMM Cluster Survey (XCS-DR1). This consists of 503 optically confirmed, serendipitously detected, X-ray clusters. Of these clusters, 256 are new to the literature and 357 are new X-ray discoveries. We present 463 clusters with a redshift estimate (0.06 < z < 1.46), including 261 clusters with spectroscopic redshifts. The remainder have photometric redshifts. In addition, we have measured X-ray temperatures (T
X) for 401 clusters (0.4 < T
X < 14.7 keV). We highlight seven interesting subsamples of XCS-DR1 clusters: (i) 10 clusters at high redshift (z > 1.0, including a new spectroscopically confirmed cluster at z= 1.01); (ii) 66 clusters with high T
X (>5 keV); (iii) 130 clusters/groups with low T
X (<2 keV); (iv) 27 clusters with measured T
X values in the Sloan Digital Sky Survey (SDSS) 'Stripe 82' co-add region; (v) 77 clusters with measured T
X values in the Dark Energy Survey region; (vi) 40 clusters detected with sufficient counts to permit mass measurements (under the assumption of hydrostatic equilibrium); (vii) 104 clusters that can be used for applications such as the derivation of cosmological parameters and the measurement of cluster scaling relations. The X-ray analysis methodology used to construct and analyse the XCS-DR1 cluster sample has been presented in a companion paper, Lloyd-Davies et al.
Abstract
We present an analysis of the chemical abundance properties of ≈650 star-forming galaxies at z ≈ 0.6 – 1.8. Using integral-field observations from the K - band Multi-Object Spectrograph ...(KMOS), we quantify the N ii/Hα emission-line ratio, a proxy for the gas-phase Oxygen abundance within the interstellar medium. We define the stellar mass – metallicity relation at z ≈ 0.6 – 1.0 and z ≈ 1.2 – 1.8 and analyse the correlation between the scatter in the relation and fundamental galaxy properties (e.g. Hα star-formation rate, Hα specific star-formation rate, rotation dominance, stellar continuum half-light radius and Hubble-type morphology). We find that for a given stellar mass, more highly star-forming, larger and irregular galaxies have lower gas-phase metallicities, which may be attributable to their lower surface mass densities and the higher gas fractions of irregular systems. We measure the radial dependence of gas-phase metallicity in the galaxies, establishing a median, beam smearing-corrected, metallicity gradient of ΔZ/ΔR= 0.002 ± 0.004 dex kpc−1, indicating on average there is no significant dependence on radius. The metallicity gradient of a galaxy is independent of its rest-frame optical morphology, whilst correlating with its stellar mass and specific star-formation rate, in agreement with an inside-out model of galaxy evolution, as well as its rotation dominance. We quantify the evolution of metallicity gradients, comparing the distribution of ΔZ/ΔR in our sample with numerical simulations and observations at z ≈ 0 – 3. Galaxies in our sample exhibit flatter metallicity gradients than local star-forming galaxies, in agreement with numerical models in which stellar feedback plays a crucial role redistributing metals.
We present results on the structural properties of massive passive galaxies in three clusters at 1.39 < z < 1.61 from the KMOS Cluster Survey. We measure light-weighted and mass-weighted sizes from ...optical and near-infrared Hubble Space Telescope imaging and spatially resolved stellar mass maps. The rest-frame R-band sizes of these galaxies are a factor of ∼2-3 smaller than their local counterparts. The slopes of the relation between the stellar mass and the light-weighted size are consistent with recent studies in clusters and the field. Their mass-weighted sizes are smaller than the rest-frame R-band sizes, with an average mass-weighted to light-weighted size ratio that varies between ∼0.45 and 0.8 among the clusters. We find that the median light-weighted size of the passive galaxies in the two more evolved clusters is ∼24% larger than that for field galaxies, independent of the use of circularized effective radii or semimajor axes. These two clusters also show a smaller size ratio than the less evolved cluster, which we investigate using color gradients to probe the underlying gradients. The median color gradients are ∇z − H ∼ −0.4 mag dex−1, twice the local value. Using stellar populations models, these gradients are best reproduced by a combination of age and metallicity gradients. Our results favor the minor merger scenario as the dominant process responsible for the observed galaxy properties and the environmental differences at this redshift. The environmental differences support that clusters experience accelerated structural evolution compared to the field, likely via an epoch of enhanced minor merger activity during cluster assembly.
We present data for 16 galaxies in the overdensity JKCS 041 at as part of the K-band Multi-Object Spectrograph (KMOS) Cluster Survey (KCS). With 20 hr integrations, we have obtained deep ...absorption-line spectra from which we derived velocity dispersions for seven quiescent galaxies. We combined photometric parameters derived from Hubble Space Telescope images with the dispersions to construct a fundamental plane (FP) for quiescent galaxies in JKCS 041. From the zero-point evolution of the FP, we derived a formation redshift for the galaxies of , corresponding to a mean age of 1.4 0.2 Gyr. We tested the effect of structural and velocity dispersion evolution on our FP zero-point and found a negligible contribution when using dynamical mass-normalized parameters ( ) but a significant contribution from stellar-mass-normalized parameters ( ). From the relative velocities of the galaxies, we probed the 3D structure of these 16 confirmed members of JKCS 041 and found that a group of galaxies in the southwest of the overdensity had systematically higher velocities. We derived ages for the galaxies in the different groups from the FP. We found that the east-extending group had typically older galaxies ( Gyr) than those in the southwest group (0.3 0.2 Gyr). Although based on small numbers, the overdensity dynamics, morphology, and age results could indicate that JKCS 041 is in formation and may comprise two merging groups of galaxies. This result could link large-scale structure to ages of galaxies for the first time at this redshift.