Abdominal pregnancy is a rare occurrence and the location is hardly seen in the upper abdomen. We described a case of a 34-year-old female presenting with upper abdominal pain and reflex sensitivity ...in the right shoulder. Ultrasound examination revealed a mass under the diaphragm which was suspected to be a liver abscess. The result of an enhanced CT scan was suggestive of an ectopic pregnancy between the diaphragm and right liver lobe. However, Laparoscopic surgery was performed and the histopathological examination confirmed the diagnosis of diaphragmatic pregnancy. By describing this case, we aim to share the value of patients with consistent upper abdominal pain and elevated serum hCG level, a thorough examination of the upper abdomen and pelvic with US as well as CT or MRI is crucial for timely diagnosis.
•Digitization and visualization of variants was used to develop a relationship with toughness.•The increase of niobium induced more HAGBs in CGHAZ.•Niobium alloying impacted variant pairing and ...consequently influenced toughness in the heat affected zone.
We have addressed here a scientific gap of elucidating the significance of Nb on impact toughness of coarse-grained heat affected zone (CGHAZ) in a structural steel, from the perspective of crystallographic structure, particularly, digitization and visualization of variant pairing. At Nb content of 0.03 wt%, there was a dominance of V1/V8 pairing such that the density of low angle grain boundaries (LAGBs) was high. However, with the increase of Nb content to 0.06 wt%, the bainite transformation temperature was decreased in conjunction with the significant decrease in V1/V8 pair and increase in V1/V2 pair. This transition in variant pair from V1/V8 to V1/V2 with increase in Nb content was responsible for superior toughness in CGHAZ together with high density of high angle grain boundaries (HAGBs).
In this paper, a simplified physical model of standing wave thermoacoustic engines (SWTE) is developed based on thermodynamic analysis. Transient pressure drop and heat transfer data are first ...calculated based on linear thermoacoustic theory. The effects of stack spacing, charge pressure, and resonator length on onset temperature were investigated and compared with experimental results. The calculations agree well with the experimental results, which validates the model for calculating the onset conditions.
•The oxide film on BN-SS304 is more chemically stabile than that on CP-SS304.•BN-SS304 scarcely suffered from pitting corrosion in 0.5M HCl for 30 days’ immersion.•The corrosion rate of Cr atom in ...BN-SS304 is less than that in CP-SS304.•The resistance of oxide film on BN-SS304 is larger than that on CP-SS304.•The oxide film on BN-SS304 is more impact than that on CP-SS304.
The electronic structures and compositions of the two oxide films on bulk nanocrystalline 304 stainless steel (BN-SS304) and its conventional polycrystalline counterpart (CP-SS304) after 30 days’ immersion test in 0.5mol/L HCl solution at room temperature were studied by X-ray photoelectron spectroscopy. The enhanced uniform and pitting corrosion resistances of BN-SS304 were attributed to the larger resistance and better chemical stability of the oxide film on BN-SS304, the less corrosion rate of Cr0 for BN-SS304 and the larger atomic percentage of Cr3+ in the oxide film on BN-SS304. The larger resistance of oxide film on BN-SS304 resulted from the less state densities of valence electrons around Fermi level in the oxide film on BN-SS304. The better chemical stability of oxide film on BN-SS304 was attributed to (1) the larger binding energies of Fe2+ 2p3/2, Fe3+ 2p3/2 and Cr3+ 2p3/2 in the oxide film on BN-SS304; (2) the larger atomic percentages of Cr3+ and Fe2+ in the oxide film on BN-SS304.
Efficient photosynthesis is critical for plant survival and growth. When plant-absorbed light exceeds the overall rate of energy conversion, it will trigger photooxidation. In this study, we selected ...a photooxidation mutant 812HS, it was isolated from the progeny of japonica rice (
Oryza sativa
L.) 812S and shows leaf yellowing and hypersensitive to photooxidation. Chloroplast ultrastructure in the leaves of 812HS showed that photooxidation resulted in significant chloroplast damage compared with 812S for changes in gene expressions in response to photooxidation stress using next-generation sequencing technologies on an Illumina HiSeq 2000 platform. A total of 88508 and 88495 genes were identified from 812S and 812HS, respectively. Expressions of 1199 genes were significantly upregulated, while 1342 genes were remarkably downregulated in 812HS. These genes were notably enriched in the 21 KEGG pathways. Based on their expression patterns, several key pathways were identified to be involved in the photooxidation of 812HS. qRT-PCR analysis further confirmed the results of RNA-Seq. This study enabled us to integrate analysis of RNA-Seq in rice and offered a deeper insight into the molecular mechanisms in response to photo-oxidative stress and provided clues for further critical gene identification in the protective mechanisms against photooxidation.
Starch characteristics determine the quality of various products of rice, e.g., eating, cooking and processing qualities. Our previous study indicated that molecular markers inside or close to starch ...synthesizing genes can differentiate the starch properties of 56 waxy rices. Here we report microsatellite (or simple sequence repeat, SSR) polymorphism in the Waxy (Wx) gene, soluble starch synthase I gene (SS1) and starch branching enzyme 1 gene (SBE1), single nucleotide polymorphism (SNP) in Wx and starch branching enzyme 3 gene (SBE3), and a sequence tagged site (STS) in starch branching enzyme 1 gene (SBE1) among 499 nonwaxy rice samples and their relationships with starch physicochemical properties. The nonwaxy rice samples consist of landraces (n = 172) obtained from germplasm centers and cultivars and breeding lines (n = 327) obtained from various breeding programs. Ten (CT) n microsatellite alleles, (CT)₈, (CT)₁₀, (CT)₁₁, (CT)₁₂, (CT)₁₇, (CT)₁₈, (CT)₁₉, (CT)₂₀, (CT)₂₁, and (CT)₂₂, were found at the Wx locus, of which (CT)₁₁ was the most frequent, and (CT)₁₂, (CT)₂₁ and (CT)₂₂ were identified for the first time. Four (CT) n microsatellite alleles were found at the SBE1 locus, (CT)₈, (CT)₉, and (CT)₁₀ together with an insertion sequence of CTCTCGGGCGA, and (CT)₈ alone without the insertion, of which (CT)₉ and the insertion was a new allele identified in only one rice, IR1552. Multiple microsatellites clustered at the SS1 locus, and in addition to the three alleles previously detected (SSS-A = (AC)₂...TCC(TC)₁₁...(TC)₅C(ACC)₁₁, SSS-B = (AC)₃...TCT(TC)₆...(TC)₄C(ACC)₉, and SSS-C = (AC)₃...TCT(TC)₆...(TC)₄C(ACC)₈), one new allele (SSS-D = (AC)₂...TCC(TC)₁₀...(TC)₄C(ACC)₉) was found. Analysis of the starch physicochemical properties of the samples with different microsatellites, SNPs and STS groups indicated that these molecular markers can differentiate almost all the physicochemical properties examined, e.g., apparent amylose content (AAC), pasting viscosity characteristics, and gel textural properties. Wx SSR and Wx SNP alone explained more variations for all physicochemical properties than the other molecular markers. The total six markers could explain 92.2, 81 and 86% of total variation of AAC, gel hardness (HD), and gel cohesiveness (COH), respectively, and they could explain more than 40% of the total variation of hot paste viscosity (HPV), cool paste viscosity (CPV), breakdown viscosity (BD), setback viscosity (SB) and gel adhesiveness (ADH). However, only 29% of the total variation of peak viscosity (PV) and 37% of pasting temperature (PT) could be explained by all the molecular markers. Some of these markers can differentiate the starch physicochemical properties among the rice samples with the same Wx allele, indicating that the variation within Wx allele classes can be explained by other starch synthesizing genes. These SSRs, SNPs and STS are useful in marker-assisted breeding for the improvement of starch quality of rice.
The nonlinear oscillations and resonant responses of the symmetric cross-ply composite laminated plates are investigated theoretically and experimentally. The governing equations of motion for the ...composite laminated plate are derived by using the von Karman type equation, Reddy’s third-order shear deformation plate theory, and Galerkin method with the geometric nonlinearity. The four-dimensional averaged equation is obtained by using the method of multiple scales. The frequency-response functions are analyzed under the consideration of strongly coupled of two modes. The influences of the resonance case on the softening and hardening type of nonlinearity are analyzed with different parameters for the composite laminated plates. The numerical results indicate that there exist the hardening and softening types of the composite laminated plate in the specific resonant case. The variation of the response amplitudes is studied for the composite laminated plate under combined the transverse and in-plane excitations. A sweep frequency experiment is performed to obtain the hardening and softening nonlinearities of a composite laminated plate. The experimental results coincide with the numerical results qualitatively. The influences of the excitation amplitudes on the softening and hardening types of nonlinearity are also analyzed for the composite laminated plate. The amplitude spectrums of the test plate also demonstrate that the change of the nonlinear dynamic responses may be caused by the subharmonic resonance.
To describe the current status of registration and design characteristics of clinical trials of new drugs for curing hepatitis B through domestic and foreign websites, so as to provide references for ...the follow-up clinical trials of new hepatitis B drugs.
A search was conducted on the US Clinical Trials Database and the Chinese Clinical Trial Registry Center. The search date was from the establishment of the database to May 26, 2020, and the registration trials of new drugs for curing hepatitis B at home and abroad were included. Two researchers independently searched and screened the literature and extracted the data.
A total of 106 registered clinical trials of new drugs for curing hepatitis B were included (94 English registration websites and 12 Chinese registration websites), and the number of registrations had increased year by year. Among them, the proportion of therapeutic vaccines and core protein inhibitors were the highest, accounting for 27.4% (
= 29) and 22.6% (
= 24), respectively. The vast majo
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