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Bioavailability of bioactive peptides (BAPs) represents the amount of peptides absorbed through normal pathways, after oral intake, and distributed in target tissues to exhibit ...bioactive properties. The small intestine is the primary location of the gastrointestinal tract where peptide absorption mainly occurs. BAPs are beneficial to health upon reaching their physiological sites of action without structural changes. Despite the rapid and dynamic evolvement of research into food peptides, there is still a knowledge gap regarding their bioaccessibility and bioavailability for systemic circulation to targeted organs. Beside the digestive actions of endogenous proteases and peptidases, chemical and nutritional compositions of the food matrix and their physical forms (e.g., liquid, puree, gel, solid) are also critical factors that can influence the interactions, digestibility, bioaccessibility and bioavailability of BAPs. Detailed understanding of such food matrix factors can be explored for enhancing the bioavailability of BAPs and achieving their positive health effects.
•ZnO spheres fabricated via solvothermal method are with (002) polar facet exposed.•Response time of ZnO sensor for detecting 100ppm acetone is as short as 3s.•Ra/Rg toward 100ppm acetone is 33 when ...operated at 230°C.•ZnO sensor exhibits good selectivity against other toxic gases and water vapor.•Porous structure and exposure of polar facet contribute to good sensing properties.
Hierarchical nanostructured ZnO dandelion-like spheres were synthesized via solvothermal reaction at 200°C for 4h. The products were pure hexagonal ZnO with large exposure of (002) polar facet. Side-heating gas sensor based on hierarchical ZnO spheres was prepared to evaluate the acetone gas sensing properties. The detection limit to acetone for the ZnO sensor is 0.25ppm. The response (Ra/Rg) toward 100ppm acetone was 33 operated at 230°C and the response time was as short as 3s. The sensor exhibited remarkable acetone selectivity with negligible response toward other hazardous gases and water vapor. The high proportion of electron depletion region and oxygen vacancies contributed to high gas response sensitivity. The hollow and porous structure of dandelion-like ZnO spheres facilitated the diffusion of gas molecules, leading to a rapid response speed. The largely exposed (002) polar facets could adsorb acetone gas molecules easily and efficiently, resulting in a rapid response speed and good selectivity of hierarchical ZnO spheres gas sensor at low operating temperature.
Developing various nanosensors with superior performance for accurate and sensitive detection of some physical signals is essential for advances in electronic systems. Zinc oxide (ZnO) is a unique ...semiconductor material with wide bandgap (3.37 eV) and high exciton binding energy (60 meV) at room temperature. ZnO nanostructures have been investigated extensively for possible use as high-performance sensors, due to their excellent optical, piezoelectric and electrochemical properties, as well as the large surface area. In this review, we primarily introduce the morphology and major synthetic methods of ZnO nanomaterials, with a brief discussion of the advantages and weaknesses of each method. Then, we mainly focus on the recent progress in ZnO nanosensors according to the functional classification, including pressure sensor, gas sensor, photoelectric sensor, biosensor and temperature sensor. We provide a comprehensive analysis of the research status and constraints for the development of ZnO nanosensor in each category. Finally, the challenges and future research directions of nanosensors based on ZnO are prospected and summarized. It is of profound significance to research ZnO nanosensors in depth, which will promote the development of artificial intelligence, medical and health, as well as industrial, production.
Taking a prestressed concrete box girder bridge as the research object, this paper analysis the causes of transverse cracks in the middle span of small box girder and adopts external prestressed bars ...for reinforcement. Two years of monitoring data showed that the strengthening effect was good, which accumulated experience for the treatment of similar bridge structures.
It has long been established that premature leaf senescence negatively impacts the yield stability of rice, but the underlying molecular mechanism driving this relationship remains largely unknown. ...Here, we identified a dominant premature leaf senescence mutant, prematurely senile 1 (ps1-D). PS1 encodes a plant-specific NAC (no apical meristem, Arabidopsis ATAF1/2, and cup-shaped cotyledon2) transcriptional activator, Oryza sativa NAC-like, activated by apetala3/pistillata (OsNAP). Overexpression of OsNAP significantly promoted senescence, whereas knockdown of OsNAP produced a marked delay of senescence, confirming the role of this gene in the development of rice senescence. OsNAP expression was tightly linked with the onset of leaf senescence in an age-dependent manner. Similarly, ChIP-PCR and yeast one-hybrid assays demonstrated that OsNAP positively regulates leaf senescence by directly targeting genes related to chlorophyll degradation and nutrient transport and other genes associated with senescence, suggesting that OsNAP is an ideal marker of senescence onset in rice. Further analysis determined that OsNAP is induced specifically by abscisic acid (ABA), whereas its expression is repressed in both aba1 and aba2 , two ABA biosynthetic mutants. Moreover, ABA content is reduced significantly in ps1-D mutants, indicating a feedback repression of OsNAP on ABA biosynthesis. Our data suggest that OsNAP serves as an important link between ABA and leaf senescence. Additionally, reduced OsNAP expression leads to delayed leaf senescence and an extended grain-filling period, resulting in a 6.3% and 10.3% increase in the grain yield of two independent representative RNAi lines, respectively. Thus, fine-tuning OsNAP expression should be a useful strategy for improving rice yield in the future.
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This review summarizes the methods and mechanisms for improving the low-temperature capacity of lithium-ion batteries from the perspective of electrode material modification. It aims ...to reduce the negative impact of low temperatures on lithium-ion battery capacity.
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Lithium-ion batteries (LIBs) have evolved into the mainstream power source of energy storage equipment by reason of their advantages such as high energy density, high power, long cycle life and less pollution. With the expansion of their applications in deep-sea exploration, aerospace and military equipment, special working conditions have placed higher demands on the low-temperature performance of LIBs. However, at low temperatures, the severe polarization and inferior electrochemical activity of electrode materials cause the acute capacity fading upon cycling, which greatly hindered the further development of LIBs. In this review, we summarize the recent important progress of LIBs in low-temperature operations and introduce the key methods and the related action mechanisms for enhancing the capacity of the various cathode and anode materials. It aims to promote the development of high-performance electrode materials and broaden the application range of LIBs.
The phytohormone auxin regulates nearly all aspects of plant growth and development. Tremendous achievements have been made in elucidating the tryptophan (Trp)-dependent auxin biosynthetic pathway; ...however, the genetic evidence, key components, and functions of the Trp-independent pathway remain elusive. Here we report that the Arabidopsis indole synthase mutant is defective in the long-anticipated Trp-independent auxin biosynthetic pathway and that auxin synthesized through this spatially and temporally regulated pathway contributes significantly to the establishment of the apical–basal axis, which profoundly affects the early embryogenesis in Arabidopsis . These discoveries pave an avenue for elucidating the Trp-independent auxin biosynthetic pathway and its functions in regulating plant growth and development.
Significance The phytohormone indole-3-acetic acid (IAA) plays a vital role in plant growth and development. IAA can be synthesized through the precursor tryptophan (Trp), known as the Trp-dependent IAA biosynthetic pathway. However, IAA may also be synthesized through a proposed Trp-independent IAA biosynthetic pathway. Although the Trp-independent IAA biosynthesis was hypothesized 20 years ago, it remains a mystery. In this paper, we provide compelling evidence that the cytosol-localized indole synthase (INS) initiates the Trp-independent IAA biosynthetic pathway and that the spatial and temporal expression of INS plays an important role in the establishment of the apical–basal pattern during early embryogenesis, demonstrating that the Trp-dependent and -independent IAA biosynthetic pathways coordinately regulate embryogenesis of higher plants.
Crown roots constitute the majority of the rice (Oryza sativa) root system and play an important role in rice growth and development. However, the molecular mechanism of crown root formation in rice ...is not well understood. Here, we characterized a rice dominant mutant, root enhancer 1 (renl-D), which was observed to exhibit a more robust root system, increased crown root number, and reduced plant height. Molecular and genetic analyses revealed that these phenotypes are caused by the activation of a cytokinin oxidase/dehydrogenase (CKX) family gene, OsCKX4. Subcellular localization demonstrated that OsCKX4 is a cytosolic isoform of CKX. OsCKX4 is predominantly expressed in leaf blades and roots. It is the dominant CKX, preferentially expressed in the shoot base where crown root primordia are produced, underlining its role in root initiation. OsCKX4 is induced by exogenous auxin and cytokinin in the roots. Furthermore, one-hybrid assays revealed that OsCKX4 is a direct binding target of both the auxin response factor OsARF25 and the cytokinin response regulators OsRR2 and OsRR3. Overexpression and RNA interference of OsCKX4 confirmed that OsCKX4 plays a positive role in crown root formation. Moreover, expression analysis revealed a significant alteration in the expression of auxin-related genes in the renl-D mutants, indicating that the OsCKX4 mediates crown root development by integrating the interaction between cytokinin and auxin. Transgenic plants harboring OsCKX4 under the control of the root-specific promoter RCc3 displayed enhanced root development without affecting their shoot parts, suggesting that this strategy could be a powerful tool in rice root engineering.
Cu-doped WO3 hollow fibers were prepared by electrospinning technique, combined with the sol–gel method and reasonable sintering procedure. The morphology and crystal phase structure were ...characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray diffraction (XRD). The gas-sensing properties were investigated as functions of the amount of Cu element, concentration of acetone and cooling method. The 3mol% Cu-doped WO3 hollow fibers using quenching for cooling exhibit high response and good selectivity to acetone. The response of the hollow fibers to 20ppm of acetone was 6.43, which could be attributed to their high surface-to-volume ratio and junction structure. Partial substitution of W6+ in WO3 with Cu2+ and quenching treatment could lead to a triclinic phase structure, which has a low symmetry, large dipole moment and strong interaction with acetone molecules and results in a good selectivity to acetone gas. Therefore, Cu-doped WO3-based materials show the potential application for semiconducting gas sensors in the diagnosis of diabetes.
The automation and intellectualization of the manufacturing processes in the iron and steel industry needs the strong support of inspection technologies, which play an important role in the field of ...quality control. At present, visual inspection technology based on image processing has an absolute advantage because of its intuitive nature, convenience, and efficiency. A major breakthrough in this field can be achieved if sufficient research regarding visual inspection technologies is undertaken. Therefore, the purpose of this article is to study the latest developments in steel inspection relating to the detected object, system hardware, and system software, existing problems of current inspection technologies, and future research directions. The paper mainly focuses on the research status and trends of inspection technology. The network framework based on deep learning provides space for the development of end-to-end mode inspection technology, which would greatly promote the implementation of intelligent manufacturing.