Directed capillary ingrowth has long been considered synonymous with tumor vascularization. However, the vascu?lature of primary tumors and metastases is not necessarily formed by endothelial cell ...sprouting; instead, malignant tumors can acquire blood vessels via alternative vascularization mechanisms, such as intussusceptive microvascular growth, vessel co?option, and glomeruloid angiogenesis. Importantly, in response to anti?angiogenic therapies, malig?nant tumors can switch from one vascularization mechanism to another. In this article, we brielfy review the biological features of these mechanisms and discuss on their signiifcance in medical oncology.
The aim of this study was to test the utilization of a generally accepted quality criteria system (United States Public Health Services Modified Quality Criteria) in the authors' practice, in the ...cases of all ceramic inlays and onlays. 41 ceramic inlays/onlays--29 pressed and 12 laminated--were made for 28 patients. Restorations were controlled after 2 years of cementation. According to the USPHS criteria system the following characteristics were controlled: anatomic contour, marginal integrity, marginal discoloration, color match, secondary caries, and surface roughness. In addition, postoperative sensitivity, patient's satisfaction and tooth vitality were examined as well. The USPHS quality criteria system together with the complementary data proved to be an objective examination method that was easily applicable to our clinical practice. On the basis of these studies the utilization of this system together with patient's satisfaction, tooth vitality and sensitivity records appeared a good basis for a regular quality control system of ceramic inlays and onlays.
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