Rust fungi are some of the most devastating pathogens of crop plants. They are obligate biotrophs, which extract nutrients only from living plant tissues and cannot grow apart from their hosts. Their ...lifestyle has slowed the dissection of molecular mechanisms underlying host invasion and avoidance or suppression of plant innate immunity. We sequenced the 101-Mb genome of Melampsora larici-populina, the causal agent of poplar leaf rust, and the 89-Mb genome of Puccinia graminis f. sp. tritici, the causal agent of wheat and barley stem rust. We then compared the 16,399 predicted proteins of M. larici-populina with the 17,773 predicted proteins of P. graminis f. sp tritici. Genomic features related to their obligate biotrophic lifestyle include expanded lineage-specific gene families, a large repertoire of effector-like small secreted proteins, impaired nitrogen and sulfur assimilation pathways, and expanded families of amino acid and oligopeptide membrane transporters. The dramatic up-regulation of transcripts coding for small secreted proteins, secreted hydrolytic enzymes, and transporters in planta suggests that they play a role in host infection and nutrient acquisition. Some of these genomic hallmarks are mirrored in the genomes of other microbial eukaryotes that have independently evolved to infect plants, indicating convergent adaptation to a biotrophic existence inside plant cells.
The photometry of the minor body with extrasolar origin (1I/2017 U1) 'Oumuamua revealed an unprecedented shape: Meech et al. (2017) reported a shape elongation b/a close to 1/10, which calls for ...theoretical explanation. Here we show that the abrasion of a primordial asteroid by a huge number of tiny particles ultimately leads to such elongated shape. The model (called the Eikonal equation) predicting this outcome was already suggested in Domokos et al. (2009) to play an important role in the evolution of asteroid shapes.
(Abridged) The Maunakea Spectroscopic Explorer (MSE) is an end-to-end science platform for the design, execution and scientific exploitation of spectroscopic surveys. It will unveil the composition ...and dynamics of the faint Universe and impact nearly every field of astrophysics across all spatial scales, from individual stars to the largest scale structures in the Universe. Major pillars in the science program for MSE include (i) the ultimate Gaia follow-up facility for understanding the chemistry and dynamics of the distant Milky Way, including the outer disk and faint stellar halo at high spectral resolution (ii) galaxy formation and evolution at cosmic noon, via the type of revolutionary surveys that have occurred in the nearby Universe, but now conducted at the peak of the star formation history of the Universe (iii) derivation of the mass of the neutrino and insights into inflationary physics through a cosmological redshift survey that probes a large volume of the Universe with a high galaxy density. MSE is positioned to become a critical hub in the emerging international network of front-line astronomical facilities, with scientific capabilities that naturally complement and extend the scientific power of Gaia, the Large Synoptic Survey Telescope, the Square Kilometer Array, Euclid, WFIRST, the 30m telescopes and many more.
55 Cnc e is a transiting super-Earth (radius $1.88\rm\,R_\oplus$ and mass $8\rm\, M_\oplus$) orbiting a G8V host star on a 17-hour orbit. Spitzer observations of the planet's phase curve at 4.5 µm ...revealed a time-varying occultation depth, and MOST optical observations are consistent with a time-varying phase curve amplitude and phase offset of maximum light. Both broadband and high-resolution spectroscopic analyses are consistent with either a high mean molecular weight atmosphere or no atmosphere for planet e. A long term photometric monitoring campaign on an independent optical telescope is needed to probe the variability in this system. We seek to measure the phase variations of 55 Cnc e with a broadband optical filter with the 30 cm effective aperture space telescope CHEOPS and explore how the precision photometry narrows down the range of possible scenarios. We observed 55 Cnc for 1.6 orbital phases in March of 2020. We designed a phase curve detrending toolkit for CHEOPS photometry which allows us to study the underlying flux variations of the 55 Cnc system. We detected a phase variation with a full-amplitude of $72 \pm 7$ ppm but do not detect a significant secondary eclipse of the planet. The shape of the phase variation resembles that of a piecewise-Lambertian, however the non-detection of the planetary secondary eclipse, and the large amplitude of the variations exclude reflection from the planetary surface as a possible origin of the observed phase variations. They are also likely incompatible with magnetospheric interactions between the star and planet but may imply that circumplanetary or circumstellar material modulate the flux of the system. Further precision photometry of 55 Cnc from CHEOPS will measure variations in the phase curve amplitude and shape over time this year.
Asteroseismology of stars in clusters has been a long-sought goal because the assumption of a common age, distance and initial chemical composition allows strong tests of the theory of stellar ...evolution. We report results from the first 34 days of science data from the Kepler Mission for the open cluster NGC 6819 -- one of four clusters in the field of view. We obtain the first clear detections of solar-like oscillations in the cluster red giants and are able to measure the large frequency separation and the frequency of maximum oscillation power. We find that the asteroseismic parameters allow us to test cluster-membership of the stars, and even with the limited seismic data in hand, we can already identify four possible non-members despite their having a better than 80% membership probability from radial velocity measurements. We are also able to determine the oscillation amplitudes for stars that span about two orders of magnitude in luminosity and find good agreement with the prediction that oscillation amplitudes scale as the luminosity to the power of 0.7. These early results demonstrate the unique potential of asteroseismology of the stellar clusters observed by Kepler.
A robust analytical method, using reversed-phase high-performance liquid chromatography with gradient elution and photodiode-array detection, was used to measure six purines and beta-NAD+ in ...acid-soluble extracts of samples taken from six different regions of human term placenta. Resolution of the analyte peaks in chromatographic profiles of the extracts, and the use of optimized integration, allowed simultaneous quantitation of all seven analytes from a single chromatogram. Peak purity was confirmed via on-line analysis of peak spectra, utilizing the purity parameter treatment of spectral data. Major placental purines were adenosine, inosine, hypoxanthine and adenine. Except for adenine, concentrations of the purines varied by two-fold or more between different regions of each placenta, but concentration ratios, i.e., adenosine/inosine and inosine/hypoxanthine, were similar. The findings indicate that the pathway of ATP breakdown to hypoxanthine in ischemic human term placenta is via adenosine, and that regional differences in placental concentrations of adenosine and its metabolites may result from regional differences in degree of ischemia.
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