U razdoblju od posljednjih pet godina na Klinici za očne bolesti Kliničke bolnice "Sestre milosrdnice" osam bolesnica je hospitalizirano radi obrade i terapije kavernozne karotidne fistule. Cilj ove ...studije bio je prikazati naša iskustva u dijagnostici, terapiji i praćenju bolesnika s kavernoznim karotidnim fistulama. Svi pacijenti bile su žene u menopauzi srednje životne dobi 69,75±7,3 godina, bez ikakve traume u anamnezi. Najčešći simptomi bili su proptoza, pad vida i kemoza. Od dijagnostičkih metoda rabili smo ultrazvuk, magnetsku rezonanciju (NMR) i angiografiju. Endovaskularna balonska okluzija bila je terapija izbora kod svih bolesnica, ali je kod jedne došlo do spontanog zatvaranja fistule, dok je jedna odbila takvu vrstu liječenja. Na prvom pregledu, mjesec dana nakon terapije, došlo je do poboljšanja očnog statusa. Simptomi kao bol, šum, kemoza, pulsacije bulbusa, glavobolje i dvoslike nisu bili prisutni. Zamijećen je mnogo manji periorbitalni edem, proptoza i dilatacija retinalnih vena, te niže vrijednosti intraokularnog tlaka. Razdoblje praćenja bilo je šest mjeseci i nije zamijećena ponovna pojava fistule. Takve spontane fistule opisane u ovoj studiji su duralni šantovi s predilekcijom u postmenopauzalnih žena, najvjerojatnije zbog ateroskleroze, hipertenzije i promjena u zgrušavanju krvi povezanih s hormonskim statusom.
The primary open-angle glaucomas are a group of diseases that have in common characteristic morphological changes at the optic nerve head and retinal nerve fiber layer, progressive retinal ganglion ...cells death and characteristic visual field loss. The risk for primary open angle glaucoma rises continuously with the level of the intraocular pressure. The disease advances slowly and there are no symptoms. Primary open angle glaucoma is caused by abnormal aqueous humour outflow in the trabecular meshwork in the open angle. Etiopathogenesis of primary open angle glaucoma is unclear. The increased risk of glaucoma in relatives has long been recognized. Frequency for manifestation of the disease is 10–30% in family members. The discovery of the specific gene loci responsible for the manifestation of glaucoma has helped us to understand its mechanism of origin and definitely confirmed the hereditary nature of this disease. Digito- -palmar dermatoglyphs were already used to determine hereditary base of many diseases and it was the reason for investigation of their qualitative patterns in patients with glaucoma (22 males and 23 females), their immediate relatives (19 males and 23 females) in comparison to a group of phenotypically healthy population (52 males and 56 females). The results pointed a connection with the dermatoglyphic traits of the digito-palmar complex between patients with glaucoma and their immediate relatives. There is a possible discrimination of patients and their immediate relatives from phenotypically healthy population, too.
A chief morbidity of Graves eye disease is eyelid retraction and exophthalmus. Transpalpebral orbital fat removal
accomplished with full thickness anterior blepharotomy was performed in 4 patients (5 ...orbits). Preoperative and postoperative
ocular exposure symptoms, visual acuity, upper eyelid retraction and proptosis were evaluated. In all 5 operated
orbits preoperative symptoms resolved; good results were achieved from the functional and cosmetic point of view.
Full-thickness anterior blepharotomy combined with fat decompression is a safe and effective surgery for patients with
upper eyelid retraction and exophthalmus due to enlarged orbital fat compartment.
Patient with primary open angle glaucoma (PAOG), which is known to have a genetic predisposition, and their immediate relatives unaffected with PAOG, may have some changes in dermatoglyphic traits of ...the digito-palmar complex, since the trabecular meshwork develops at the same time and with the same hereditary base like dermatoglyphs, which have high genetic transmission. The objective of this study is to determine whether differences in quantitative dermatoglyphic traits of the digito-palmar complex exist between patients with glaucoma and the phenotipically healthy population and whether their family members have the same dermatoglyphic changes. The quantitative dermatoglyphic traits in patients suffering from glaucoma, first-degree members of their family and the phenotypically healthy population have been screened in this study. Descriptive statistics, univariate analysis of variance (ANOVA) and post hoc (Tukey HSD) method have been used. The results have shown that there is a link between the quantitative dermatoglyphic traits of the digito-palmar complex in patients affected by glaucoma and a first-degree healthy member of their family, as well as the difference between patients with glaucoma and their first-degree relatives, which may discriminate them from the phenotypically healthy population. The results of the study mostly affirm the existence of genetic predisposition for the development of primary open-angle glaucoma, thus emphasizing the relevance of hereditary factors in the etiopathogenesis of this disease.
The patients with uveitic glaucoma are at high risk for failure following drainage surgery because of young age of
these patients, preoperative long-term control of inflammation and postoperative ...complications. Twenty-two trabeculectomies
performed in 22 patients with uveitic glaucoma were retrospectively evaluated to analyze the effect of
intraoperative application of mitomycin C (MMC). Success rates, postoperative levels of intraocular pressure (IOP)
and postoperative complications were studied. After a mean follow-up of 10.6 months (range, 5–28 months), 15 patients
(68.2%) achieved IOP of 21mmHg or less without antiglaucoma medications. There were statistically significant
reduction in IOP postoperatively during the period studied (p<0.001). Early postoperative complications included chorioidal
detachment (9.1%), shallow anterior chamber (9.1%), hyphema (13.6%), macular edema (4.5%) and raised IOP
(27.3%). Late postoperative complications included exacerbation of uveitis (4.5%), macular edema (4.5%), cataract
(22.7%) and raised IOP (31.8 %). The eyes with raised IOP needed additional antiglaucoma medication. The results of
this retrospective and uncontrolled study suggest that intraoperative application of MMC may be a good option for enhancement
of short-term trabeculectomy success rates in patients with uveitic glaucoma.
