Amaç: Nötrofil jelatinaz ilişkili lipokalin (NGAL) immun regülasyonla ilişkili bir nöromediatördür. Obsesif kompulsif bozuklukta (OKB) hastalık-hemogram ilişkisiyle ilgili çalışma sayısı azdır. ...Çalışmamızda ilk kez tanı konan OKB hastalarında hastalık şiddeti ile kan NGAL düzeyi ve hemogram arasındaki ilişki araştırılmıştır. Yöntem: Ocak 2018-Ocak 2020 tarihleri arasında psikiyatri polikliniğine ayaktan başvuran 28050 hasta değerlendirildi. İlk atak OKB tanı-sı konulan ve çalışmaya katılmayı kabul eden 32 hastanın Yale Brown Obsesyon Kompulsiyon Skalası (Y-BOCS) ile hastalık şiddeti araştırıldı; periferik kan NGAL düzeyi, hemogram ölçüldü ve immun regülasyon ile ilişkili olarak toplam lökosit sayısı, % nötrofil granülosit (NEU%) değerlendirildi, C reaktif protein (CRP) bakıldı. Bulgular: İlk kez tanı konan OKB hastalarında NEU% ve CRP değerlerinde anlamlı farklılık saptanırken, kan NGAL düzeylerinde fark saptanmadı. Y-BOCS puanları arttıkça kan hemoglobin (Hb) ve hematokrit (Hct) değerlerinin azaldığı belirlendi. Sonuç: İlk kez tanı alan OKB hastalarında diğer inflamatuar mediatörlerde artış saptanırken, plazma NGAL düzeyi ile hastalık ve hastalık şiddeti arasında anlamlı bir artış yoktur, bu alan yazındaki ilk yayındır. OKB hastalarında hastalık şiddetinin artması Hb ve Hct düzeylerini etkilemektedir.
INTRODUCTION: Premature newborns are defined as babies born before 37 weeks of pregnancy and after 22 weeks of pregnancy as a viability limit. Aim of this study was to analyze growth characteristics ...at the age of second and third age and prevention of metabolic diseases that may occur in adult age at an early phase. METHODS: This study was conducted as a retrospective cohort study between May 2018 and October 2018 in 18 different Family Medicine Outpatient Clinics in Rize, Central district. All participants were at least 3 years old and their follow-up visits made by the same family physicians for 3 years. RESULTS: It was found that 54.66% of babies were males(n=123), 45.33% of them were females(n=102). According to BMI (Body Mass İndex) evaluations, 19.11% of babies were overweight(n=43), 16% of them were obese(n=36) at the age of two and 20% of them were overweight (n=45), 13.33% of them were obese(n=30) at the age of three. The mean Hb levels of the mothers whom children were obese at the age of two were statistically lower than the others (p<0.001). DISCUSSION AND CONCLUSION: According to WHO, worldwide prevalance of childhood overweight and obesity was 6.70% in 2010 and it is expected to reach 9.10% in 2020. When we searched reasons of high overweight and obesity prevalance, there wasn't significant difference related with maternal factors and feeding patterns. We found significant relationship between maternal anemia and being overweight and obesity at the age of two.
It is known that being hospitalized in the intensive care unit (ICU) for any reason is a risk factor for future psychiatric problems. This qualitative study aims to identify the experiences of ...coronavirus disease 2019 (COVID-19) ICU survivors and provide insights for relevant mental health problems after being discharged. Participants were COVID-19 patients discharged from ICUs of a secondary care hospital. The experiences of 21 ICU survivors were evaluated using Colaizzi's 7-step approach, which were determined by the purposeful sampling method. There were three themes generated from the interviews as "emotions on COVID-19 diagnosis," "feelings about ICU stay and health care providers," and "life in the shadow of COVID-19." Two subthemes for every single theme were generated, and a total of 19 codes were extracted. It is essential to understand the individual's unique experiences in designing preventive interventions and apply individual preventive mental health interventions during ICU stay.
Asthma can be classified into atopic and non-atopic phenotypes. However, limited data are available on the clinical implications of these two phenotypes in real life.
This study aimed to examine the ...clinical features as well as control level and disease severity of asthmatic patients with their aeroallergen sensitivity profiles.
Between 2013 and 2020, adult asthmatic patients who had been followed up regularly at our tertiary healthcare institution for at least one year were included in the study. We collected data retrospectively using manually filled patient files.
The mean age of 382 asthmatic patients was 46.6 ± 30.0; 77.5% were women and 75.6% had at least one aeroallergen sensitivity. Polysensitized asthmatics had better asthma symptom control and milder asthma severity than monosensitized asthmatics. Asthma symptom control status was well controlled in 67.5% of the patients, and according to asthma severity, 51.3% of the patients were classified as having moderate asthma. There was a negative relation between age (OR:0.95, CI:0.92–0.98) and atopy presence. The presence of atopy was higher in moderate asthmatics than in mild asthmatics (OR:2.02, CI:1.01–4.09). Finally, there was a positive relationship between the percent predicted forced expiratory volume in first second (FEV1%) (OR:1.02, CI:1.009–1.048) and the presence of atopy. The presence of rhinitis (OR:0.44, CI:0.22–0.88) and per 1 unit increase of Tiffeneau index (FEV1/forced vital capacity) (OR:0.94, CI:0.90–0.99) had a negative association, whereas number of medication use for asthma symptoms (OR:1.68, CI:1.18–2.39) and presence of cardiovasculary disease (OR:2.64, CI:1.19–5.84) had a positive association with not well-controlled asthma symptom level.
Aeroallergen sensitivity was associated with asthma severity. However, this was not the case with asthma control levels in this adult asthma cohort. Among the atopic asthmatics polysensitized asthmatics had better asthma symptom control level and milder asthma severity level.
Asthma and COPD management have a broad framework, and smoking cessation plays an essential role. We examine the management of asthma and COPD patients not only for inhaler treatment options but also ...for essential interventions, such as smoking cessation support.
Data were collected cross-sectionally from pulmonology departments of three government hospitals in Türkiye between May and September 2022. Patients aged ≥18 years who had been diagnosed with asthma or COPD for at least a year, were included in the study. The demographic and clinical characteristics of the patients were investigated. Routine cessation interventions were implemented for current smokers, and they were followed via phone calls after one month regarding their quit status and access to cessation clinics.
Data from 145 patients with asthma and 148 patients with COPD were analyzed. The rate of current smoking among patients with asthma and COPD was 18.8% and 34.5%, respectively. Current smoking was negatively associated with age (<65 years) and disease duration (years) for both diseases (p<0.05). In addition, for asthmatics, presence of pulmonary disease in the family (OR:0.28, 95% CI: 0.10-0.79) and for COPD patients presence of hospitalization (OR: 0.26, 95% CI: 0.07-0.93) were negatively associated with current smoking. After one month, 85.1% of current asthmatic smokers had not tried to call a quitline, while 14.8% had tried to contact a quitline. Among current smoker COPD patients, only 1.9% had visited a smoking cessation clinic.
Tobacco cessation support seems to be neglected in asthma and COPD management. Instead, pulmonologists and patients focus on pharmaceutical treatments, which constitute the other component of care.
Background
The effect of COVID‐19 on smoking behavior is not fully known. Studies evaluating the link between smoking and COVID‐19 have controversial results. This study aims to evaluate patients' ...smoking status with COVID‐19 and the effect of COVID‐19 on smoking behavior.
Methods
Data were collected from 150 COVID‐19 patients with a positive polymerase chain reaction test for SARS‐CoV‐2 between 11 March 2020 and 15 May 2020 in Rize, Turkey. Patients were interviewed by phone calls 2 months after their recovery. After 9 months, a follow‐up was performed for those who quit smoking.
Results
Of the participants, 19 (12.7%) were current smokers before the COVID‐19 diagnosis, and 15 (78.9%) of them stated that they quit smoking after their diagnosis. After nine months of follow‐up, 11 of those 15 participants (57.8%) sustained abstinence.
Conclusion
Smoking cessation rates are high in people with COVID‐19. Besides, the frequency of sustaining abstinence in the long term was also high in these individuals. The COVID‐19 pandemic should be viewed as an open opportunity to strengthen and prioritize smoking cessation activities.
PDF
